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"Burkitt lymphoma (BL) is a form of non-Hodgkin's lymphoma in which cancer starts in immune cells called B-cells. If left untreated, it is rapidly fatal. Chapter One of this monograph evaluates the etiology, pathological issues, diagnosis, clinical manifestations, epidemiology, research, innovation and treatment issues of BL using the clinical systematic review research method and experts' opinion analysis approach. Chapter Two reviews the spectrum, unique characteristics and special management considerations when BL develops in specific subgroups of patients with primary immune deficiency disorders. Chapter Three reviews the incidence, clinicopathological and epidemiologic features, treatment and outcome data available in pediatric and adult patients with post solid organ transplant BL. Chapter Four focuses on the pathobiology and the treatment of first-line and relapsed/refractory cases of BL and describes new therapeutic strategies which could improve results in this pathology. Chapter Five examines the therapeutic advances in BL and its variants. Finally, Chapter Six explores and emphasizes the trends and issues in research and innovation in the characteristics, clinical updates and management approaches of BL"--
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Burkitt's lymphoma. --- Internal medicine --- Oncology --- Hematology, lymphology --- Burkitt's lymphoma --- Tumeur de Burkitt --- Oncology. --- Hematology, lymphology.
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The Epstein-Barr virus (EBV) was discovered in 1964. At the time, the very idea of a virus underlying a cancer was revolutionary. Cancer is, after all, not catching. Even now, the idea of a virus causing cancer surprises many people. But Epstein-Barr, named after its discoverers, Sir Anthony Epstein and Dr Yvonne Barr, is fascinating for other reasons too. Almost everyone carries it, yet it is only under certain circumstances that it produces disease. It has been associated withdifferent, apparently unrelated, diseases in different populations: Burkitt's Lymphoma, producing tumours in the jaw,
Epstein-Barr virus. --- Viral carcinogenesis. --- Microbial carcinogenesis --- Oncogenic viruses --- Burkitt herpesvirus --- Burkitt's lymphoma virus --- E-B virus --- EBV (Virus) --- Human herpesvirus-4 --- Infectious mononucleosis virus --- Herpesviruses --- Oncogenic DNA viruses
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Burkitt's lymphoma. --- Fiber deficiency diseases. --- Surgeons. --- Operating room personnel --- Physicians --- Dietary fiber deficiency --- Deficiency diseases --- High-fiber diet --- African lymphoma --- Burkitt tumor --- Burkitt's African lymphoma --- Burkitt's tumor --- B cells --- Epstein-Barr virus diseases --- Tumors --- Limfomes --- Cirurgia
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This volume aims to bring together efforts with a patient-oriented focus from physicians to diagnostics and clinical implications of the disease as mostly seen in the equatorial African setting. However, the chapters cover the breadth of studies on Burkitt’s lymphoma with some clues for the potential future of Burkitt’s lymphoma research that can have therapeutic benefits for patients. This text explore a range of topics associated with Burkitt’s lymphoma, including molecular biology, diagnosis, its association with AIDS and Malaria, immune responses, therapeutic approaches and a unique view from the bedside. This volume is comprehensive and unique and represents the most up-to-date clinical and research activities on Burkitt’s lymphoma.
Burkitt''s lymphoma. --- Epstein-Barr Virus Infections --- Lymphoma, B-Cell --- Lymphoma, Non-Hodgkin --- Tumor Virus Infections --- Herpesviridae Infections --- Lymphoma --- Lymphoproliferative Disorders --- DNA Virus Infections --- Virus Diseases --- Neoplasms, Experimental --- Neoplasms --- Neoplasms by Histologic Type --- Immunoproliferative Disorders --- Diseases --- Lymphatic Diseases --- Hemic and Lymphatic Diseases --- Immune System Diseases --- Burkitt Lymphoma --- Medicine --- Health & Biological Sciences --- Oncology --- Burkitt's lymphoma. --- African lymphoma --- Burkitt tumor --- Burkitt's African lymphoma --- Burkitt's tumor --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- B cells --- Epstein-Barr virus diseases --- Tumors --- Oncology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Physiological effect
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Recently, understanding the molecular pathogenesis of malignant lymphomas has led to improvement in the diagnostic precision and to the identification of a variety of molecular therapeutic targets. In addition, new drugs have been approved in the US and Europe, resulting in changes in the standard of care of several types of lymphoid malignancies. Comprehensive in scope and developed by a team of internationally renowned authors, Lymphoma: Diagnosis and Treatment provides a timely update on the most important advances in the biology, diagnosis, and therapy of lymphomas. As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies.
Burkitt's lymphoma. --- Lymphomas --- Neoplasms by Histologic Type --- Neoplasms --- Diseases --- Lymphoma --- Medicine --- Health & Biological Sciences --- Oncology --- Diagnosis. --- Treatment. --- Germinoblastomas --- Immunoblastomas --- Non-Hodgkin's lymphoma --- Reticulolymphosarcomas --- Sarcoma, Germinoblastic --- Sarcoma, Immunoblastic --- Medicine. --- Cancer research. --- Hematology. --- Oncology. --- Medicine & Public Health. --- Cancer Research. --- Lymphoproliferative disorders --- Reticulo-endothelial system --- Tumors --- Oncology . --- Haematology --- Internal medicine --- Blood --- Cancer research
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Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Microbiology & Immunology --- Biology --- Health & Biological Sciences --- Epstein-Barr virus. --- Epstein-Barr virus diseases. --- EBV diseases --- Burkitt herpesvirus --- Burkitt's lymphoma virus --- E-B virus --- EBV (Virus) --- Human herpesvirus-4 --- Infectious mononucleosis virus --- Medicine. --- Virology. --- Biomedicine. --- Microbiology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Herpesvirus diseases --- Chronic fatigue syndrome --- Herpesviruses --- Oncogenic DNA viruses --- Medical virology. --- Medical microbiology --- Virology --- Virus diseases
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Herpesvirus 4, Human. --- Neoplasms --- Burkitt's Lymphoma Virus --- HHV-4 --- Herpesvirus 4 (gamma), Human --- Burkitt Herpesvirus --- Burkitt Lymphoma Virus --- E-B Virus --- EBV --- Epstein-Barr Virus --- Human Herpesvirus 4 --- Infectious Mononucleosis Virus --- Burkitts Lymphoma Virus --- E B Virus --- E-B Viruses --- Epstein Barr Virus --- Herpesvirus, Burkitt --- Infectious Mononucleosis Viruses --- Lymphoma Virus, Burkitt --- Mononucleosis Virus, Infectious --- Mononucleosis Viruses, Infectious --- etiology. --- Oncology. Neoplasms --- Medical microbiology, virology, parasitology --- Herpesvirus 4, Human --- etiology
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Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Oncology --- Medicine --- Health & Biological Sciences --- Epstein-Barr virus. --- Epstein-Barr virus diseases. --- EBV diseases --- Burkitt herpesvirus --- Burkitt's lymphoma virus --- E-B virus --- EBV (Virus) --- Human herpesvirus-4 --- Infectious mononucleosis virus --- Medicine. --- Cancer research. --- Immunology. --- Virology. --- Infectious diseases. --- Animal models in research. --- Biomedicine. --- Cancer Research. --- Infectious Diseases. --- Animal Models. --- Animal experimentation --- Biological models --- Laboratory animals --- Research --- Microbiology --- Immunobiology --- Life sciences --- Serology --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Herpesvirus diseases --- Chronic fatigue syndrome --- Herpesviruses --- Oncogenic DNA viruses --- Oncology. --- Medical virology. --- Emerging infectious diseases. --- Laboratory animals. --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Medical microbiology --- Virology --- Virus diseases --- Tumors --- Infection --- Infectious diseases --- Diseases --- Causes and theories of causation --- Cancer. --- Diseases. --- Biology --- Cancer Biology. --- Experimental Organisms. --- Technique. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Human beings --- Illness --- Illnesses --- Morbidity --- Sickness --- Sicknesses --- Epidemiology --- Health --- Sick
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