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Brugada syndrome --- Bundle-branch block --- Ventricular fibrillation
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With upwards of 4.5 million deaths worldwide each year, and more than one tenth of these occurring in those with no previously documented heart disease, sudden arrhythmic death (SAD) is both a major public health burden and a highly emotive issue for society at large. Recent years have witnessed a marked expansion in our knowledge of the physiology underlying SAD, both in the context of hereditary and acquired cardiac disorders. Thanks largely to work in genetically modified animals, the growth in our understanding of mechanisms underlying arrhythmia in the hereditary channelopathies has been particularly marked. Our growing knowledge of the fundamental mechanisms underlying SAD has so far failed to spur substantial developments in clinical practice. Despite a large body of work in both humans and animals, it remains impossible to confidently identify those at high risk of SAD, making pre-emptive therapy a challenge. What is more, with the thankful exception of the implantable cardioverter-defibrillators and pharmacological agents in very specific situations, there has been depressingly little progress in finding new and effective therapies. This Research Topic aims to go some way towards bridging the gap between advances in basic science and the development and delivery of new therapies. It brings together original research contributions and review articles from key opinion leaders in the field, focusing on the direct clinical implications of the basic science research now and in the future.
Sudden death. --- Sudden death --- Cardiac arrest --- Prevention. --- Pathophysiology. --- Death --- Mortality --- Causes --- Arrest, Cardiac --- Cardiopulmonary arrest --- Heart arrest --- Sudden cardiac death --- Heart --- Heart failure --- Diseases --- ventricular arrhythmia --- Inherited arrhythmia syndromes --- sudden death --- arrhythmia mechanisms --- Channelopathies --- ventricular tachycardia --- cardiac modelling --- Ventricular Fibrillation --- Atrial Fibrillation --- Brugada Syndrome
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Nutrition, often along with physical activity, is by now acknowledged as a cornerstone in the prevention and even more so the treatment of many diseases. Indeed, food and nutritional intake nowadays are often thought to be the main source of wellbeing sometimes over- but also underestimating the impact of nutritional intake, dietary pattern and food-derived natural compounds in their impact on human health. In this Special Issue entitled `Clinical Nutrition: Recent Advances and Remaining Challenges´ a broad overview and summary on recent findings in various fields of clinical nutrition with special focus on chronic and degenerative diseases like metabolic diseases, cancers, neurodegenerative diseases, inflammatory bowel diseases, sarcopenia but also malnutrition in elderly, infants and children is provided. Nutrition, often along with physical activity, is by now acknowledged as a cornerstone in the prevention and even more so the treatment of many diseases. Indeed, food and nutritional intake nowadays are often thought to be the main source of wellbeing sometimes over- but also underestimating the impact of nutritional intake, dietary pattern and food-derived natural compounds in their impact on human health. In this Special Issue entitled `Clinical Nutrition: Recent Advances and Remaining Challenges´ a broad overview and summary on recent findings in various fields of clinical nutrition with special focus on chronic and degenerative diseases like metabolic diseases, cancers, neurodegenerative diseases, inflammatory bowel diseases, sarcopenia but also malnutrition in elderly, infants and children is provided.
Research & information: general --- Biology, life sciences --- Food & society --- malnutrition --- cirrhosis --- nutritional screening --- nutritional assessment --- gut–liver axis --- macronutrients --- micronutrients --- dysbiosis --- diet --- enteral nutrition --- inflammatory bowel disease --- nutrition --- nutritional therapy --- prevention --- artificial nutrition --- nasogastric feeding --- nasogastric tube --- palliative care --- calcium oxalate stone formation --- dietary assessment --- fatty acids --- fluid --- oxalate --- protein --- sodium --- uric acid --- water --- insulin --- lifestyle --- non-alcoholic --- steatohepatitis --- fibrosis --- metabolic syndrome --- weight loss --- time-restricted feeding --- intermittent fasting --- low-carb diet --- liver disease --- Brugada syndrome --- long QT syndrome --- ingredients --- glucose --- ketone bodies --- ROS --- sudden cardiac death --- bariatric surgery --- cardiovascular disease --- endovascular bariatric surgery --- obesity --- oral nutritional supplements --- perioperative nutrition --- sarcopenia --- gastrointestinal surgery --- behaviour --- nutrition supplements --- type 2 diabetes --- ageing --- inflammaging --- anorexia of aging --- DoMAP --- GLIM criteria --- cholestasis --- chronic liver diseases --- nutritional needs --- pediatrics --- medical nutrition therapy --- critical care --- parenteral nutrition --- energy --- review --- Crohn’s disease --- gut microenvironment --- celiac disease --- gluten --- gluten-free diet --- prostate --- metabolism --- benign prostatic hyperplasia --- erectile dysfunction --- dietary recommendation --- overweight --- carbohydrate --- fat
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