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The brain's vast array of responsibilities includes the regulation of all physical movements, memory, learning and emotions, as well as the reception and interpretation of all sensory inputs. These numerous responsibilities require the facility of a very complex organ, and the brain is complex, to say the least. The brain’s complexity provides a constant challenge for scientists to explore new theories. This book presents and discusses topical data in the field of brain research, with a particular emphasis placed on brain mapping and diseases. -- Publisher
Brain mapping. --- Brain --- Diseases.
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This dissertation by Helene van explores neural language patterns in healthy adults, focusing on the roles of Broca’s and Wernicke’s areas. It examines how these brain regions contribute to language abilities, using functional magnetic resonance imaging (fMRI) to correlate language performance with brain activation. The study involves healthy adults and individuals with generalized epilepsy. Key findings indicate a shift in neural activation laterality related to language performance, with high semantic ability linked to right posterior temporal lobe activation and decreased left inferior frontal gyrus activation. The research suggests a complex interaction between cognitive capacity and neural adaptability in language processing. The intended audience includes researchers and professionals in neuroscience and cognitive science.
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This dissertation by Anders Eklund focuses on computational medical image analysis with an emphasis on real-time functional magnetic resonance imaging (fMRI) and statistical methods. The work presents methods for real-time fMRI, which is crucial for interactive brain mapping and brain-computer interfaces. It also covers statistical approaches for fMRI analysis, including random permutation tests to calculate significance thresholds and p-values. The dissertation aims to improve the understanding of brain function and assist in clinical applications, such as planning surgeries and brain activity control. The intended audience includes biomedical engineers, neurologists, psychologists, and researchers in medical imaging.
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This dissertation explores the neurobiological mechanisms and aetiology of narcolepsy, focusing on the dynamics of brain networks in adolescents with Type 1 narcolepsy. Utilizing various neuroimaging techniques, the research identifies structural and functional deviations in brain regions, particularly related to Orexin-A loss, which affects cognition and metabolism. The study finds correlations between brain anomalies and cognitive performance, highlighting potential therapeutic targets. Additionally, it examines the relationship between narcolepsy and weight gain, suggesting that changes in Orexin may influence adipose tissue distribution rather than volume. The work aims to advance understanding of narcolepsy's impact on brain function and its broader implications for health.
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Connectome Analysis: Characterization, Methods, and Analysis is a comprehensive companion for the analysis of brain networks, or connectomes. The book provides sources of constituent structural and functional MRI signals, network construction and practices for analysis, cutting-edge methods that address the latest challenges in neuroscience, and the fundamentals of network theory in the context of giving practical methods for building connectomes for analysis. Emphasis is placed on quality control of the individual analysis steps. Subsequent chapters discuss networks in neuroscience in clinical and general populations, including how findings are related to underlying neurophysiology and neuropsychology.This book is aimed at students and early-career researchers in brain connectomics and neuroimaging who have a background in computer science, mathematics and physics, as well as more broadly to neuroscientists and psychologists who want to start incorporating connectomics into their research.
Cognitive Neuroscience --- Neuropsychology --- Psychology --- Brain Mapping. --- Brain mapping
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Brain Warping is the premier book in the field of brain mapping to cover the mathematics, physics, computer science, and neurobiological issues related to brain spatial transformation and deformation correction. All chapters are organized in a similar fashion, covering the history, theory, and implementation of the specific approach discussed for ease of reading. Each chapter also discusses the computer science implementations, including descriptions of the programs and computer codes used in its execution. Readers of Brain Warping will be able to understand all of the approaches
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A survey of the views of recognised authorities of the present day, as given in this book, tends to show that, whereas other branches of medical science have made great advances during the nineteenth century, our knowledge of the mental functions of the brain is still obscure, and deviations from the normal mind remain little understood and far off from cure. Much value has been attached to the experiments on the brains of animals, but all they can demonstrate amounts to a differentiation of sensory and motor areas; they must ever fail to shed light on the diversity of human talents and dispositions and the variety of mental derangements. The present work aims at clearing up the mystery of the fundamental psychical functions and their localisation in the brain. It is the first work on the subject since the dawn of modern scientific research. While most previous investigators have confined their attention to the intellect alone, the author considers also the emotions and passions of man, normal and abnormal, and demonstrates their connection with the brain. Even the most recent textbooks deem insanity to be a disease of the brain implicating the whole of that organ. Whether a person be melancholic, violently maniacal, homicidal, or suffer from delusions of persecution, whether he be a kleptomaniac, a religious maniac, or fancy himself a millionaire--in every case it is assumed that the whole cortex is affected, whereas the evidence adduced by the author shows that the fundamental varieties of mental derangement are localised in definite circumscribed regions, and frequently are, in the early stages at least, amenable to treatment. Brain surgery should, if future investigators confirm the author's observations, receive an immense stimulus to activity; and the data amassed by the author, and published in this work, are so considerable as to open up quite a new field for research. The author has based his localisations chiefly on clinical and pathological investigations. Over eight hundred cases are adduced, not merely of the recognised varieties of mental derangement, but of all kinds of deviation from the normal mind, even as regards the manifestation of hunger and thirst. The book contains numerous cases of interest to lawyers, as well as physicians, and should prove of value to all students of human character. The author found that his localisations confirm those made a century ago by Gall, whose marvelous discoveries of the anatomy and physiology of the brain--on which Spurzheim built his system of Phrenology--were ignored even by his most scientific followers, so that the world is ignorant of them, and they are presented for the first time in this book. The history of Gall and his doctrine is given in these pages, and will be quite a revelation to the reader. No subject has ever been so thoroughly misrepresented, even by learned men of acknowledged authority, and no author has ever been so labeled and with such malice as Gall, and this notwithstanding the fact that there is not one man of scientific repute who has mitten anything which would indicate that he has examined, Gall's chief work: "Anatomie et physiologie du systeme nerveux en general, et du cerveau en particulier." The fact that they have not read Gall's great work should make those who have any bias on this subject pause and reflect--at least until they have read this book carefully and examined the evidence therein set forth. Considering the important bearing which the facts contained in this work may possibly have upon the entire development of mental science, on the study and treatment of lunacy, on the education of the young, the precocious alike and the feeble-minded, on moral reform, the diminution of crime, and many other problems affecting the well-being of the community, the author trusts that the evidence and statements, which he produces after fifteen years of investigation, may be received willingly and in fair spirit, however critical.
Brain --- Phrenology. --- Brain mapping. --- Diseases.
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Brain mapping --- Brain --- Neural networks (Neurobiology) --- Imaging
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