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Book
Bone marrow pathology
Authors: --- ---
ISBN: 9781119398127 1119398126 9781119398912 9781119398899 Year: 2019 Publisher: Hoboken, NJ Wiley-Blackwell


Book
Myeloproliferative neoplasms : critical concepts and management
Authors: ---
ISBN: 3642249884 3642249892 9786613577450 1280399538 Year: 2012 Publisher: New York : Springer,

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Abstract

Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. The current book focuses on three of these categories: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. A number of important questions regarding the diagnosis, prognosis, and treatment of these diseases have arisen following the discovery of the JAK2 V617F mutation in the majority of patients with bcr/abl-negative MPNs.   This book comprises evidence-based reviews and expert consensus results. It offers comprehensive coverage of relevant laboratory and clinical advances and places great emphasis on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic  approaches, the value and limitations of mutation screening for diagnostic and  prognostic purposes, risk stratification in terms of both survival and other  disease complications such as leukemic transformation and thrombosis, and  modern therapeutic strategies, including conventional drugs, allogeneic stem cell  transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.


Book
Bone and cancer
Authors: ---
ISBN: 1848820186 9786612931611 128293161X 1848820194 Year: 2009 Publisher: London : Springer,

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Bone and Cancer is the fifth volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. This title features current knowledge on mechanisms of metastasis, the role of the bone microenvironment in cancer progression, how inflammatory cytokines function in metastasis and osteolysis, and the role of osteoblasts, thus bringing to the clinician and researcher cellular and molecular findings that affect the search for drugs and lead to translational studies. Each chapter contains an extensive bibliography that permits readers to learn more about specific aspects of the chapter topic. Tables, diagrams and figures illustrate and clarify cellular events that lead to development and progression of cancer in bone. Insights based on cellular and molecular events clarify the clinical picture and may lead to translational research and focused therapy. The chapters, authored by authorities from throughout the world, emphasize how current knowledge can lead to better treatement. Other titles in this series:- Bone Formation Bone Resorption Engineering of Functional Skeletal Tissues Bone and Osteoarthritis.


Book
Myeloproliferative neoplasms : biology and therapy
Authors: ---
ISBN: 1607612658 9786612972140 1282972146 1607612666 Year: 2011 Publisher: New York : Humana Press,

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Abstract

This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.


Book
Biology and Treatment of Leukemia and Bone Marrow Neoplasms
Authors: ---
ISBN: 3030783111 3030783103 Year: 2021 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.

Keywords

Leucèmia --- Medul·la òssia --- Quimioteràpia del càncer --- Ciències de la salut --- Biomedicina --- Ciències biomèdiques --- Ciències mèdiques --- Ciències de la vida --- Fisiologia humana --- Microbiologia mèdica --- Neurociències --- Quimioteràpia anticancerosa --- Quimioteràpia antineoplàsica --- Quimioteràpia --- Medicaments antineoplàstics --- Sistema immunitari --- Trastorns mieloproliferatius --- Anèmia --- Càncer --- Leucèmia aguda --- Leucèmia en els infants --- Leucèmia mieloide --- Acute leukemia. --- Leukemia --- Leukemia. --- Leukemia, Myeloid, Acute. --- Myelodysplastic Syndromes. --- Bone Marrow Neoplasms. --- Neoplasms, Bone Marrow --- Bone Marrow Neoplasm --- Neoplasm, Bone Marrow --- Hematopoetic Myelodysplasia --- Dysmyelopoietic Syndromes --- Dysmyelopoietic Syndrome --- Hematopoetic Myelodysplasias --- Myelodysplasia, Hematopoetic --- Myelodysplasias, Hematopoetic --- Myelodysplastic Syndrome --- Syndrome, Dysmyelopoietic --- Syndrome, Myelodysplastic --- Syndromes, Dysmyelopoietic --- Syndromes, Myelodysplastic --- ANLL --- Acute Myelogenous Leukemia --- Acute Myeloid Leukemia --- Acute Myeloid Leukemia with Maturation --- Acute Myeloid Leukemia without Maturation --- Leukemia, Acute Myelogenous --- Leukemia, Acute Myeloid --- Leukemia, Myeloblastic, Acute --- Leukemia, Myelocytic, Acute --- Leukemia, Myeloid, Acute, M1 --- Leukemia, Myeloid, Acute, M2 --- Leukemia, Nonlymphoblastic, Acute --- Myeloblastic Leukemia, Acute --- Myelocytic Leukemia, Acute --- Myelogenous Leukemia, Acute --- Myeloid Leukemia, Acute, M1 --- Myeloid Leukemia, Acute, M2 --- Nonlymphoblastic Leukemia, Acute --- Leukemia, Myelogenous, Acute --- Leukemia, Nonlymphocytic, Acute --- Myeloid Leukemia, Acute --- Nonlymphocytic Leukemia, Acute --- Acute Myeloblastic Leukemia --- Acute Myeloblastic Leukemias --- Acute Myelocytic Leukemia --- Acute Myelocytic Leukemias --- Acute Myelogenous Leukemias --- Acute Myeloid Leukemias --- Acute Nonlymphoblastic Leukemia --- Acute Nonlymphoblastic Leukemias --- Acute Nonlymphocytic Leukemia --- Acute Nonlymphocytic Leukemias --- Leukemia, Acute Myeloblastic --- Leukemia, Acute Myelocytic --- Leukemia, Acute Nonlymphoblastic --- Leukemia, Acute Nonlymphocytic --- Leukemias, Acute Myeloblastic --- Leukemias, Acute Myelocytic --- Leukemias, Acute Myelogenous --- Leukemias, Acute Myeloid --- Leukemias, Acute Nonlymphoblastic --- Leukemias, Acute Nonlymphocytic --- Myeloblastic Leukemias, Acute --- Myelocytic Leukemias, Acute --- Myelogenous Leukemias, Acute --- Myeloid Leukemias, Acute --- Nonlymphoblastic Leukemias, Acute --- Nonlymphocytic Leukemias, Acute --- Leucocythaemia --- Leucocythemia --- Leucocythaemias --- Leucocythemias --- Leukemias --- Myeloproliferative Disorders --- Hematologic Neoplasms --- Terapèutica --- Teràpia --- Tractament (Medicina) --- Tractament de les malalties --- Medicina clínica --- Al·lopatia (Terapèutica) --- Antipirètics --- Cateterisme --- Dietoteràpia --- Fisioteràpia --- Fórmules magistrals --- Hormonoteràpia --- Immunoteràpia --- Injeccions intraarticulars --- Intubació --- Ioga --- Logopèdia --- Medicina alternativa --- Nutrició --- Radiologia intervencionista --- Terapèutica dental --- Terapèutica fisiològica --- Teràpia genètica --- Teràpia intravenosa --- Teràpia respiratòria --- Terapèutica veterinària --- Tractament pal·liatiu --- Ús terapèutic --- Leucèmia granulocítica --- Leucèmia mielocítica --- Leucèmia mielògena --- Hematology. --- Oncology. --- Medicine --- Biology --- Biomedical Research. --- Research. --- Biological research --- Biomedical research --- Health Workforce --- Tumors --- Haematology --- Internal medicine --- Blood --- Diseases

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