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This guidance document has been prepared to support technical aspects of the OECD skin absorption test guidelines. In particular is discusses the various aspects of in vivo vs. in vitro testing.

Skin --- Cutis --- Integument (Skin) --- Beauty, Personal --- Body covering (Anatomy) --- Skin.

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Skin tumors are very often encountered in clinical practice but can be difficult to diagnose since the skin's histological complexity gives rise to many types and subtypes. This superb atlas presents an unrivalled wealth of original high-quality clinical photographs of almost all benign and malignant skin tumors. The diverse subtypes and clinical forms, including different localizations, are depicted, and careful attention is paid to evolution and follow-up. While the main focus is on the clinical presentation as reflected in the photographs, diagnostic clues and management considerations are also summarized in a straightforward, readily understandable way. The atlas has been designed so that it will meet clinical needs and allow rapid identification of clues relevant to daily practice. Clinical Atlas of Skin Tumors will be valuable for all dermatologists in training, as well as for those who are already established in the profession or in allied specialties such as plastic surgery and oncology.

Skin --- Tumors --- Cancer --- Cutis --- Integument (Skin) --- Beauty, Personal --- Body covering (Anatomy) --- Dermatology. --- Oncology  . --- Oncology. --- Medicine --- Diseases

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Photodynamic therapy has been widely investigated over the past two decades and is emerging as a promising therapeutic modality for skin cancers and several inflammatory diseases. This growing interest is based on the availability of a new simple, effective and safe regimen using the topical application of a pro-drug, 5-aminolevulinic acid, as well as on the development of new ""second generation"" photosensitizers, namely 5-aminolevulinic acid-esters, phthalocyanines, chlorins, porphycenes and hypericin. In contrast to hematoporphyrin derivatives, these compounds are characterized by short-la

Skin --- Diseases --- Photochemotherapy. --- Cutis --- Integument (Skin) --- Beauty, Personal --- Body covering (Anatomy)

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This book provides a practically applicable resource for all clinicians managing patients with or who may develop melanoma. Each chapter focuses on clinically relevant information on the latest advances in the field, including techniques for early detection of skin cancers, cross-sectional imaging and staging of regional nodes. Algorithms for clinical decision-making along with clinical vignettes are incorporated into each chapter, enabling the reader to develop a deep understanding of how to manage a range of scenarios. Practical Manual for Dermatologic and Surgical Melanoma Management systematically details the latest diagnostic criteria, treatment guidelines and management techniques available for treating these patients and is a valuable resource for the trainee and practising clinician. .

Skin --- Cancer --- Treatment. --- Cancer. --- Cutis --- Integument (Skin) --- Beauty, Personal --- Body covering (Anatomy) --- Dermatology. --- Medicine --- Diseases

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Virtually all sites in the human body can host lesions that simulate neoplasms, and many of these ""pseudotumors"" can simulate neoplasms on all levels of analysis-- clinical, radiologic, and pathologic-- thus they represent particular diagnostic pitfalls for the pathologist that can ultimately lead to therapeutic misdirection. This book provides the pathologist with detailed morphologic descriptions and diagnostic guidance in recognizing these neoplastic mimics as they occur in the skin. In addition, descriptions and diagnostic guidance are provided for the range of skin lesions that may mimi

Skin --- Cutis --- Integument (Skin) --- Beauty, Personal --- Body covering (Anatomy) --- Diseases --- Diagnosis. --- Pathophysiology.