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This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revis
Diphosphonates --- Bones --- Osteology --- Musculoskeletal system --- Bone --- Skeleton --- Biphosphonates --- Bisphosphonates --- Phosphonates --- Therapeutic use. --- Diseases --- Chemotherapy.
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Clinical osteology is now an independent specialty which nevertheless encompasses all branches of medicine and effects each and every one of us: Bone is Every Body´s Business: This book has been designed as an up to date manual to deal with the currently recognized indications for bisphosphonates, to outline situations and conditions for prevention of skeletal disorders, and to provide practical guidelines for treatment. It is intended for doctors who seek precise information on bisphosphonates in medical practice to enable them to treat patients with disorders of bone or better still to avoid their occurrence – as the age-old saying has it "prevention is better than cure”! Significant advances have already been made in the first 6 years of the "Bone and Joint Decade” of the new century, it is our hope that this book will contribute to more progress in the same direction.
Diphosphonates --- Bones --- Therapeutic use. --- Side effects. --- Diseases. --- Biphosphonates --- Bisphosphonates --- Phosphonates --- Internal medicine. --- Orthopedics. --- Gynecology. --- Surgery. --- Internal Medicine. --- Surgery, Primitive --- Medicine --- Gynaecology --- Generative organs, Female --- Medicine, Internal --- Orthopaedics --- Orthopedia --- Surgery --- Diseases --- Gynecology .
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Bone Diseases --- Diphosphonates --- Bones --- Calcium --- Os --- drug therapy. --- metabolism. --- therapeutic use. --- pharmacology. --- Therapeutic use. --- Diseases --- Chemotherapy. --- Metabolism --- Disorders --- Emploi en thérapeutique --- Maladies --- Chimiothérapie --- Métabolisme, Troubles du --- Emploi en thérapeutique --- Chimiothérapie --- Métabolisme, Troubles du --- Biphosphonates --- Bisphosphonates --- Phosphonates --- Alkaline earth metals --- High-calcium diet --- Osteology --- Musculoskeletal system --- Bone --- Skeleton --- Diseases&delete& --- Chemotherapy --- Metabolism&delete& --- Disorders&delete& --- Therapeutic use --- drug therapy --- metabolism --- pharmacology --- therapeutic use
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Bisphosphonates are commonly prescribed to inhibit bone loss in patients with osteoporosis, as well as osteopenia, cancer, and Paget's disease of the bone. Recently, scientific literature has addressed a possible relationship between bisphosphonates and osteonecrosis of the jaw (ONJ). It is important to note that though the risks for developing ONJ are much higher for cancer patients on intravenous bisphosphonate therapy (used to reduce bone pain), the occurrence of ONJ also in patients treated with oral BF for osteoporosis has been also highlighted, though rarely. On the basis of the large use of BF, of their pharmacokinetics, of the systemic and local risk factors, physicians prescribing them and dental surgeons should be well informed on the various aspects of the problem. Aim of this volume is to offer an update on the current status of prevention, and on the current conservative and surgical treatments. The multidisciplinary approach will be very much appreciated by GP’s, the different specialists using bisphosphonates and by dental surgeons.
Bones -- Necrosis. --- Diphosphonates -- Physiological effect. --- Jaws -- Necrosis. --- Temporomandibular joint --- Organophosphorus Compounds --- Organic Chemicals --- Chemicals and Drugs --- Diphosphonates --- Medicine --- Dentistry --- Health & Biological Sciences --- Diseases by Body Region --- Oral Surgery --- TMJ Diseases --- Diseases --- Jaws --- Bones --- Necrosis. --- Physiological effect. --- Biphosphonates --- Bisphosphonates --- Osteonecrosis --- Phossy jaw --- Dentistry. --- Pharmacy. --- Medicine. --- General practice (Medicine). --- Radiology. --- Hematology. --- Oral surgery. --- Maxillofacial surgery. --- Medicine & Public Health. --- Oral and Maxillofacial Surgery. --- General Practice / Family Medicine. --- Imaging / Radiology. --- Phosphonates --- Surgery. --- Family medicine. --- Radiology, Medical. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Chemistry --- Drugs --- Materia medica --- Pharmacology --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Haematology --- Internal medicine --- Blood --- Dental surgery --- Odontology --- Surgery, Dental --- Oral medicine --- Teeth --- Surgery, Primitive --- Oral surgery --- Surgery, Oral --- Oral surgeons --- Radiological physics --- Physics --- Radiation
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