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This book presents the basic principles of time-of-flight (TOF) mass spectrometry with a strong emphasis on applications in biological research. It describes many innovative techniques, including orthogonal extraction, post source decay, and delayed extraction, and surveys ionization techniques used on TOF mass spectrometers such as electron impact, plasma desorption, SIMS, FAB, laser desorption, MALDI, and electrospray. The book features chapters on applications to peptides/proteins, oligonucleotides, and other biological macromolecules, and examines how techniques might be used in sequencing the human genome.

Biomolecules --- Analysis. --- Mass spectrometry. --- Biomolecules - Analysis.

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Biological techniques --- fysicochemie --- Molecular biology --- Organic spectroscopy --- Biomolecules --- Analysis. --- Mass spectrometry --- Congresses --- Analysis --- Biomolecules - Analysis.

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Proteins --- Mass Spectrometry --- Proteomics. --- Biomolecules --- Analysis --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Proteins - Analysis --- Biomolecules - Analysis --- Acqui 2006

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Biological techniques --- fysicochemie --- Human biochemistry --- Clinical chemistry --- Organic spectroscopy --- Biochemistry --- Biomolecules --- Mass Spectrometry --- Technique --- Analysis --- Mass spectrometry. --- Spectrum Analysis, Mass. --- Technique. --- Analysis. --- Biochemistry - Technique --- Biomolecules - Analysis

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Infra-red spectrometry --- Infrared spectrometry --- Infrared spectroscopy --- Infrarode spectroscopie --- Spectrometry [Infrared ] --- Spectroscopie [Infrarode ] --- Spectroscopie infrarouge --- Spectroscopy [Infrared ] --- Infrared spectroscopy. --- Biomolecules --- Analysis. --- Analysis --- Biomolecules - Analysis.