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The development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers. Moreover it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequisite for reliable pacemaking, or simpler structures might work as well. This book gives an overview of the current state-of-the-art of creating a bio-engineered pacemaker. It shows the approaches to develop of genetic and cell-based engineering methods suitable to implement them with safety and stability. It also illuminates the problems that need to be solved before bio-pacemaking can be considered for clinical use.
Biological rhythms. --- Pacemaker cells. --- Mathematical Sciences --- Applied Mathematics --- Engineering. --- Human physiology. --- Cardiology. --- Application software. --- Biophysics. --- Biological physics. --- Biomedical engineering. --- Biomedical Engineering. --- Human Physiology. --- Computer Applications. --- Biophysics and Biological Physics. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Biological physics --- Biology --- Medical sciences --- Physics --- Application computer programs --- Application computer software --- Applications software --- Apps (Computer software) --- Computer software --- Heart --- Internal medicine --- Human biology --- Physiology --- Human body --- Construction --- Industrial arts --- Technology --- Diseases --- Biological pacemakers --- Natural pacemakers --- Pacemakers, Biological --- Cells --- Biological rhythms --- Biological clocks --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Periodicity --- Computer science. --- Biomedical Engineering and Bioengineering. --- Biological and Medical Physics, Biophysics. --- Informatics --- Science
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Asie --- Azië --- Therapieën --- Thérapies --- Acupuncture. --- Biological Clocks. --- Energy Metabolism. --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Bioenergetics --- Energy Expenditure --- Bioenergetic --- Energy Expenditures --- Energy Metabolisms --- Expenditure, Energy --- Expenditures, Energy --- Metabolism, Energy --- Metabolisms, Energy --- Pharmacopuncture --- Acupuncture Therapy --- Acupuncture --- Biological Clocks --- Energy Metabolism
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Biological rhythms --- Human biology --- Rythmes biologiques --- Biologie humaine --- Biological Clocks. --- Biology --- Physical anthropology --- Biological clocks --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Periodicity --- Biological rhythms. --- Human biology. --- Biological Clocks
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Acclimatization. --- Biological Clocks. --- Climate. --- Periodicity. --- Physiology, Comparative. --- Comparative Physiology --- Biological Rhythms --- Bioperiodicity --- Biorhythms --- Cyclicity --- Rhythmicity --- Biological Rhythm --- Bioperiodicities --- Biorhythm --- Cyclicities --- Periodicities --- Rhythm, Biological --- Rhythmicities --- Rhythms, Biological --- Climates --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Acclimation --- Climate --- Acclimatization --- Biological Clocks --- Periodicity --- Physiology, Comparative
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Physiology. --- Biological Clocks. --- Circadian Rhythm. --- #TS:WDEP --- 57 --- 57.034 --- 57.034 Cyclic variations, oscillation. Rhythmicity. --- Cyclic variations, oscillation. Rhythmicity. --- Nycthemeral Rhythm --- Diurnal Rhythm --- Nyctohemeral Rhythm --- Twenty-Four Hour Rhythm --- Circadian Rhythms --- Diurnal Rhythms --- Nycthemeral Rhythms --- Nyctohemeral Rhythms --- Rhythm, Circadian --- Rhythm, Diurnal --- Rhythm, Nycthemeral --- Rhythm, Nyctohemeral --- Rhythm, Twenty-Four Hour --- Rhythms, Circadian --- Rhythms, Diurnal --- Rhythms, Nycthemeral --- Rhythms, Nyctohemeral --- Rhythms, Twenty-Four Hour --- Twenty Four Hour Rhythm --- Twenty-Four Hour Rhythms --- Biological Clocks --- Photoperiod --- Chronotherapy --- Circadian Clocks --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Biological sciences in general --- Periodicals --- Biology --- Chronobiology --- Physiology
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In an important new contribution to the literature of chaos, two distinguished researchers in the field of physiology probe central theoretical questions about physiological rhythms. Topics discussed include: How are rhythms generated? How do they start and stop? What are the effects of perturbation of the rhythms? How are oscillations organized in space? Leon Glass and Michael Mackey address an audience of biological scientists, physicians, physical scientists, and mathematicians, but the work assumes no knowledge of advanced mathematics.Variation of rhythms outside normal limits, or appearance of new rhythms where none existed previously, are associated with disease. One of the most interesting features of the book is that it makes a start at explaining "dynamical diseases" that are not the result of infection by pathogens but that stem from abnormalities in the timing of essential functions. From Clocks to Chaos provides a firm foundation for understanding dynamic processes in physiology.
Biomathematics. Biometry. Biostatistics --- General biophysics --- Biological rhythms --- Mathematics --- Biological Clocks. --- Mathematics. --- Periodicity. --- 57.034 --- -Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Biological Rhythms --- Bioperiodicity --- Cyclicity --- Rhythmicity --- Biological Rhythm --- Bioperiodicities --- Biorhythm --- Cyclicities --- Periodicities --- Rhythm, Biological --- Rhythmicities --- Mathematic --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Cyclic variations, oscillation. Rhythmicity. --- Periodicity --- Biological rhythms. --- -Cyclic variations, oscillation. Rhythmicity. --- 57.034 Cyclic variations, oscillation. Rhythmicity. --- Biological Clocks --- Biological clocks --- Cyclic variations, oscillation. Rhythmicity --- Biophysics --- Biophysique --- Biological rhythms - Mathematics --- Biological rhythms(Mathematical Study) --- Biomathematique --- Chaos
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Biological rhythms --- Congresses --- Biological Clocks. --- Ethology. --- -57.034 --- 591.543.4 --- Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Cyclic variations, oscillation. Rhythmicity. --- Alternation of climatic conditions. Seasons --- Periodicity --- Congresses. --- 591.543.4 Alternation of climatic conditions. Seasons --- 57.034 Cyclic variations, oscillation. Rhythmicity. --- Biological Clocks --- Ethology --- 57.034 --- Cyclic variations, oscillation. Rhythmicity --- Biological rhythms - Congresses
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Biological rhythms --- Endocrine glands --- Biological clocks --- Endocrine Glands --- Congresses --- physiology --- Congresses. --- Physiology --- Biological Clocks. --- 57.034 --- 591.147 --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Ductless glands --- Gland of internal secretion --- Glands, Ductless --- Glands --- Chromaffin cells --- Hormones --- physiology. --- Cyclic variations, oscillation. Rhythmicity. --- Internal secretions. Endocrine secretions. Hormones. Adrenalin. Insulin. Sex hormones. Androgens. Oestrogens --- 591.147 Internal secretions. Endocrine secretions. Hormones. Adrenalin. Insulin. Sex hormones. Androgens. Oestrogens --- 57.034 Cyclic variations, oscillation. Rhythmicity. --- Biological Clocks --- Cyclic variations, oscillation. Rhythmicity --- Biological rhythms - Congresses --- Endocrine glands - Congresses --- Biological clocks - Congresses --- Endocrine Glands - physiology - congresses
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Biological Clocks. --- Reproduction. --- Biological rhythms --- -Human reproduction --- -Human physiology --- Reproduction --- Reproductive health --- Reproductive rights --- Biological clocks --- Biology --- Biorhythms --- Endogenous rhythms --- Living clocks --- Rhythms, Biological --- Chronobiology --- Cycles --- Pacemaker cells --- Human Reproductive Index --- Human Reproductive Indexes --- Reproductive Period --- Human Reproductive Indices --- Index, Human Reproductive --- Indexes, Human Reproductive --- Indices, Human Reproductive --- Period, Reproductive --- Periods, Reproductive --- Reproductive Index, Human --- Reproductive Indices, Human --- Reproductive Periods --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Congresses --- Periodicity --- Human reproduction --- Congresses. --- -Congresses --- Biological Clocks
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Physiology of nerves and sense organs --- Circadian rhythms --- Human biology --- Biological Clocks. --- Circadian Rhythm. --- Periodicity. --- Biology --- Physical anthropology --- Behavior, Circadian --- Biological clocks, Daily --- Circadian behavior --- Circadian clocks --- Circadian cycles --- Clocks, Circadian --- Cycles, Circadian --- Daily activity cycles --- Daily biological clocks --- Diel cycles --- Diurnal rhythms --- Rhythms, Circadian --- Biological rhythms --- Biological Rhythms --- Bioperiodicity --- Biorhythms --- Cyclicity --- Rhythmicity --- Biological Rhythm --- Bioperiodicities --- Biorhythm --- Cyclicities --- Periodicities --- Rhythm, Biological --- Rhythmicities --- Rhythms, Biological --- Ultradian Rhythms --- Diurnal Rhythm --- Nyctohemeral Rhythm --- Twenty-Four Hour Rhythm --- Circadian Rhythms --- Diurnal Rhythms --- Nyctohemeral Rhythms --- Rhythm, Circadian --- Rhythm, Diurnal --- Rhythm, Nyctohemeral --- Rhythm, Twenty-Four Hour --- Rhythm, Ultradian --- Rhythms, Diurnal --- Rhythms, Nyctohemeral --- Rhythms, Twenty-Four Hour --- Rhythms, Ultradian --- Twenty Four Hour Rhythm --- Twenty-Four Hour Rhythms --- Ultradian Rhythm --- Biological Clocks --- Photoperiod --- Chronotherapy --- Circadian Clocks --- Biologic Clock --- Biologic Oscillator --- Biological Pacemakers --- Clock, Biologic --- Clocks, Biological --- Oscillator, Biologic --- Oscillators, Biological --- Pacemaker, Biologic --- Pacemakers, Biologic --- Biological Oscillators --- Oscillators, Endogenous --- Pacemakers, Biological --- Biologic Clocks --- Biologic Oscillators --- Biologic Pacemaker --- Biologic Pacemakers --- Biological Clock --- Biological Oscillator --- Biological Pacemaker --- Clock, Biological --- Clocks, Biologic --- Endogenous Oscillator --- Endogenous Oscillators --- Oscillator, Biological --- Oscillator, Endogenous --- Oscillators, Biologic --- Pacemaker, Biological --- Chronobiology Phenomena --- Circadian Rhythm --- Sleep Disorders, Circadian Rhythm --- Nycthemeral Rhythm --- Nycthemeral Rhythms --- Rhythm, Nycthemeral --- Rhythms, Nycthemeral --- Periodicity
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