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Nanoparticles --- Nanopartícules --- Ultraestructura (Biologia)
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Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases.
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Symbiose. --- Biologia celular. --- Symbiosis.
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Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases.
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Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases.
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Although Seibutsu no Sekai (The World of Living Things), the seminal 1941 work of Kinji Imanishi, had an enormous impact in Japan, both on scholars and on the general public, very little is known about it in the English-speaking world. This book makes the complete text available in English for the first time and provides an extensive introduction and notes to set the work in context. Imanishi's work, based on a very wide knowledge of science and the natural world, puts forward a distinctive view of nature and how it should be studied. Imanishi's work is particularly important as a bac
Biology --- Vitalism --- Philosophy. --- Biología --- Filosofía
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Phoma --- Sphaeropsidaceae --- Ultraestructura (Biologia) --- Metabòlits
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Life (Biology) --- Biology --- Vida (Biologia) --- Fisiologia --- Aigua --- Animals --- Biosfera --- Cicles vitals (Biologia) --- Força vital --- Longevitat --- Mort (Biologia) --- Organismes transgènics --- Plantes --- Protoplasma --- Reproducció --- Vitalisme --- Biologia
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