Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

There is general agreement within the fields of food, nutrition, and medical sciences that an individual's diet and lifestyle can substantially predispose one to, or protect against osteoporosis, low bone mass, and numerous other age-related bone diseases. Dietary bioactives, found diversity in a variety of foods from fruits to vegetables, herbs and spices, essential oils and beverages, have the potential to influence bone health. The NIH Office of Dietary Supplements has defined dietary bioactives as "compounds that are constituents in foods and dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status." These compounds are generally thought to be safe in food at normal consumption levels (e.g., polyphenols in plant foods). Dietary bioactives are currently being assessed for their properties beyond antioxidant capacity, including anti-inflammatory actions. Some compounds or classes of compounds have been reported to enhance bone formation and inhibit bone resorption through their actions on cell signaling pathways that influence osteoblast and osteoclast differentiation. Emerging scientific evidence is available, including observational studies and small clinical interventions that suggest consumption of certain dietary bioactives may have beneficial effects on bone health. Animal models have the unique advantage of feeding controlled diets for extended periods of time to assess long-term changes in bone. While bone mineral density (BMD) is the gold standard for assessing fracture risk, other factors such as bone structure, including trabecular thickness and separation, influence bone strength. Bone turnover rate is also predictive of fracture. Future research is needed to determine the types and quantities of dietary bioactives that are most effective and at what dose, as well as the mechanisms involved in modulating cellular events, in order to set precedence for larger clinical trials.

Bioactive compounds.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Plant-derived phenolic compounds whose most important classes are flavonoids (i.e., catechin, epicatechin) quinones, stilbenes (i.e., resveratrol) and essential oils (i.e., thymol, carvacrol), widely found in fruits, seeds, flowers, and leaves, are considered as beneficial molecules for prevention and treatment of several diseases, since it has been shown that they have antioxidant, anticarcinogenic, cardioprotective, neuroprotective, and anti-inflammatory properties. The Special Issue contains contributions concerning different aspects of the use of phenolic plant-derived molecules for prevention and therapy of several diseases, in order to understand the mechanisms involved in their protective role, their bioavailability and their metabolism in human tissue. Moreover, the use of different strategies for extraction, synthesis, and delivery of these compounds, has been covered.

Bioactive compounds.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Bioactive Compounds - Biosynthesis, Characterization, and Applications is an authoritative compilation of chapters on bioactive compounds with proven activities. It provides valuable information about biosynthesized active compounds that can be used for the further development of products in various industries. Chapters cover such topics as biosynthesis, characterization, separation, and purification, and applications of bioactive molecules. It describes and discusses bioresources of animal, vegetal, and microbial origin as potential sources of flavonoids, polysaccharides, sterols, polyphenols, amino acids, and others. This book provides insight into future developments in the field and, as such, is an essential resource for academicians, industrial researchers, and practitioners in biomolecules with biological activity. Key features: - Describes several classes of bioactive compounds and their associated activities - Highlights potential contributions of bioactive compounds as alternatives in the prevention and/or treatment of diseases - Contains information relevant to the development and use of new products.

Bioactive compounds.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Bioactive compounds are abundant in nature, particularly in plants, which have the capacity to synthesize phenolics, flavonoids, caffeine, carotenoids, and much more. Different bioactive compounds can change or alter the life process due to their different biological activities. This book examines bioactive compounds and their sources, structures, and potential uses in various industries, including pharmaceuticals, medicine, cosmetics, and food processing.

Bioactive compounds.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

There is general agreement within the fields of food, nutrition, and medical sciences that an individual's diet and lifestyle can substantially predispose one to, or protect against osteoporosis, low bone mass, and numerous other age-related bone diseases. Dietary bioactives, found diversity in a variety of foods from fruits to vegetables, herbs and spices, essential oils and beverages, have the potential to influence bone health. The NIH Office of Dietary Supplements has defined dietary bioactives as "compounds that are constituents in foods and dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status." These compounds are generally thought to be safe in food at normal consumption levels (e.g., polyphenols in plant foods). Dietary bioactives are currently being assessed for their properties beyond antioxidant capacity, including anti-inflammatory actions. Some compounds or classes of compounds have been reported to enhance bone formation and inhibit bone resorption through their actions on cell signaling pathways that influence osteoblast and osteoclast differentiation. Emerging scientific evidence is available, including observational studies and small clinical interventions that suggest consumption of certain dietary bioactives may have beneficial effects on bone health. Animal models have the unique advantage of feeding controlled diets for extended periods of time to assess long-term changes in bone. While bone mineral density (BMD) is the gold standard for assessing fracture risk, other factors such as bone structure, including trabecular thickness and separation, influence bone strength. Bone turnover rate is also predictive of fracture. Future research is needed to determine the types and quantities of dietary bioactives that are most effective and at what dose, as well as the mechanisms involved in modulating cellular events, in order to set precedence for larger clinical trials.

Bioactive compounds.