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This book provides a resource for the science or medical professional interested in islet biology. With a mix of review articles and studies showing primary data, new advances in islet inflammation and metabolic homeostasis are highlighted. The topics are succinctly presented by distinct viewpoints. An introduction to the Special Issue, with summaries of the studies included, is provided by the Guest Editors.

Research & information: general --- Biology, life sciences --- beta cell death --- beta cell dysfunction --- beta cell failure --- ER stress --- hyperglycemia --- obesity --- oxidative stress --- saturated fatty acids --- beta cell hypofunction --- beta cell hyperfunction --- glucolipotoxicity --- low carbohydrate diet --- ketogenic diet --- insulin sensitivity --- pancreas --- islet of Langerhans --- proinflammatory cytokines --- NADPH oxidases --- Rac1 --- pancreatic beta cell --- diabetes --- β-cell --- macrophage --- islet --- cytokine --- insulin --- transcriptomics --- type 2 diabetes --- insulin resistance --- inflammation --- gut microbiome --- untargeted plasma metabolomics --- polyunsaturated fatty acids --- prostaglandins --- insulin secretion --- beta-cell function --- beta cell death --- beta cell dysfunction --- beta cell failure --- ER stress --- hyperglycemia --- obesity --- oxidative stress --- saturated fatty acids --- beta cell hypofunction --- beta cell hyperfunction --- glucolipotoxicity --- low carbohydrate diet --- ketogenic diet --- insulin sensitivity --- pancreas --- islet of Langerhans --- proinflammatory cytokines --- NADPH oxidases --- Rac1 --- pancreatic beta cell --- diabetes --- β-cell --- macrophage --- islet --- cytokine --- insulin --- transcriptomics --- type 2 diabetes --- insulin resistance --- inflammation --- gut microbiome --- untargeted plasma metabolomics --- polyunsaturated fatty acids --- prostaglandins --- insulin secretion --- beta-cell function

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Long noncoding RNAs (lncRNAs) are a new class of transcripts that are in general longer than 200 nucleotides and that have no protein-coding potential. The vast majority of vertebrate genomes encode diverse and complex lncRNAs that play regulatory roles at almost every step of gene expression. Recently, increasing evidence has implicated lncRNAs in the pathogenesis of various human diseases.The purpose of the Research Topic, "Emerging roles of long noncoding RNAs in neurological diseases and metabolic disorders", is to bring together leading researchers in the field who, through contributing to an organized and comprehensive collection of peer-reviewed articles, provide a broad perspective on the latest advances in the field.

Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- lncRNA --- Beta-cell --- Metabolism --- Neurological Diseases --- diabetes