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Babesiosis, caused by tick-transmitted intraerythrocytic parasites (Babesia spp.), occurs worldwide. The disease mainly affects livestock, but records of infections in humans are increasing, and the disease is considered to be emerging worldwide. This book provides a comprehensive and holistic view of Babesia species that can infect humans. Numerous experts analyze, in detail, basic aspects of the biology of Babesia, the pathology of the babesiosis highlighting the pathogenesis of babesiosis in sickle cell, the eco-epidemiology of tick vectors and the impact of climate change on them, the current status, and future prospects for laboratory diagnosis and measures to prevent transfusion transmission. The book also focused on unidentified Babesia parasites that continue to emerge, most likely from wildlife, for which neither tick vector species nor vertebrate reservoir host species are currently known. Lastly, current and new therapies for infected patients, in vitro and in vivo culture systems for antibabesial evaluation and measures to prevent infections are also considered.

Medicine --- Epidemiology & medical statistics --- babesiosis --- Babesia microti --- Babesia duncani --- parasite --- therapy --- atovaquone --- endochin-like quinolones (ELQs) --- human babesiosis --- Nantucket Island --- epidemiology --- ecology --- human risk --- European babesiosis --- Babesia divergens --- Babesia venatorum --- Ixodes ricinus --- parasite identity --- clinical cases --- diagnosis --- treatment --- Babesia --- diversity --- phylogenetic analysis --- blood transfusion --- prevention --- screening --- aspartyl protease --- plasmepsin --- apicomplexa --- piroplasmida --- BmIPA48 --- BMR1_03g00960 --- piroplasmid rhoptry-associated protein-1 (pRAP-1) --- ticks --- Babesia sp. --- biological cycle --- experimental transmission --- experimental models --- Ixodes scapularis --- climate --- global warming --- Babesia sp. MO1 --- Babesia capreoli --- rap-1a --- ama-1 --- phylogeny --- sickle-cell anemia --- hemolysis --- haemoglobinopathies --- immunoepidemiology --- case surveillance --- therapeutic drugs --- peptidases --- antibody-based assays --- nucleic acid tests --- multiplex detection --- next generation sequencing --- glycosylphosphatidylinositol --- protein structure --- antigen --- host blood analysis --- fallow deer --- ixodid ticks --- piroplasm --- red deer --- Theileria --- Babesia bovis --- Babesia bigemina --- Colombia --- n/a --- in vitro culture --- erythrocytes --- DMEM-F12 --- virulence

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Babesiosis, caused by tick-transmitted intraerythrocytic parasites (Babesia spp.), occurs worldwide. The disease mainly affects livestock, but records of infections in humans are increasing, and the disease is considered to be emerging worldwide. This book provides a comprehensive and holistic view of Babesia species that can infect humans. Numerous experts analyze, in detail, basic aspects of the biology of Babesia, the pathology of the babesiosis highlighting the pathogenesis of babesiosis in sickle cell, the eco-epidemiology of tick vectors and the impact of climate change on them, the current status, and future prospects for laboratory diagnosis and measures to prevent transfusion transmission. The book also focused on unidentified Babesia parasites that continue to emerge, most likely from wildlife, for which neither tick vector species nor vertebrate reservoir host species are currently known. Lastly, current and new therapies for infected patients, in vitro and in vivo culture systems for antibabesial evaluation and measures to prevent infections are also considered.

Medicine --- Epidemiology & medical statistics --- babesiosis --- Babesia microti --- Babesia duncani --- parasite --- therapy --- atovaquone --- endochin-like quinolones (ELQs) --- human babesiosis --- Nantucket Island --- epidemiology --- ecology --- human risk --- European babesiosis --- Babesia divergens --- Babesia venatorum --- Ixodes ricinus --- parasite identity --- clinical cases --- diagnosis --- treatment --- Babesia --- diversity --- phylogenetic analysis --- blood transfusion --- prevention --- screening --- aspartyl protease --- plasmepsin --- apicomplexa --- piroplasmida --- BmIPA48 --- BMR1_03g00960 --- piroplasmid rhoptry-associated protein-1 (pRAP-1) --- ticks --- Babesia sp. --- biological cycle --- experimental transmission --- experimental models --- Ixodes scapularis --- climate --- global warming --- Babesia sp. MO1 --- Babesia capreoli --- rap-1a --- ama-1 --- phylogeny --- sickle-cell anemia --- hemolysis --- haemoglobinopathies --- immunoepidemiology --- case surveillance --- therapeutic drugs --- peptidases --- antibody-based assays --- nucleic acid tests --- multiplex detection --- next generation sequencing --- glycosylphosphatidylinositol --- protein structure --- antigen --- host blood analysis --- fallow deer --- ixodid ticks --- piroplasm --- red deer --- Theileria --- Babesia bovis --- Babesia bigemina --- Colombia --- in vitro culture --- erythrocytes --- DMEM-F12 --- virulence --- babesiosis --- Babesia microti --- Babesia duncani --- parasite --- therapy --- atovaquone --- endochin-like quinolones (ELQs) --- human babesiosis --- Nantucket Island --- epidemiology --- ecology --- human risk --- European babesiosis --- Babesia divergens --- Babesia venatorum --- Ixodes ricinus --- parasite identity --- clinical cases --- diagnosis --- treatment --- Babesia --- diversity --- phylogenetic analysis --- blood transfusion --- prevention --- screening --- aspartyl protease --- plasmepsin --- apicomplexa --- piroplasmida --- BmIPA48 --- BMR1_03g00960 --- piroplasmid rhoptry-associated protein-1 (pRAP-1) --- ticks --- Babesia sp. --- biological cycle --- experimental transmission --- experimental models --- Ixodes scapularis --- climate --- global warming --- Babesia sp. MO1 --- Babesia capreoli --- rap-1a --- ama-1 --- phylogeny --- sickle-cell anemia --- hemolysis --- haemoglobinopathies --- immunoepidemiology --- case surveillance --- therapeutic drugs --- peptidases --- antibody-based assays --- nucleic acid tests --- multiplex detection --- next generation sequencing --- glycosylphosphatidylinositol --- protein structure --- antigen --- host blood analysis --- fallow deer --- ixodid ticks --- piroplasm --- red deer --- Theileria --- Babesia bovis --- Babesia bigemina --- Colombia --- in vitro culture --- erythrocytes --- DMEM-F12 --- virulence