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Students of evolutionary and behavioural ecology are often unfamiliar with mathematical techniques, though much of biology relies on mathematics. Evolutionary ideas are often complex, meaning that the logic of hypotheses proposed should not only be tested empirically but also mathematically. There are numerous different modelling tools used by ecologists, ranging from population genetic 'bookkeeping', to game theory and individual-based computer simulations. Due to the many different modelling options available, it is often difficult to know where to start. Hanna Kokko has designed this 2007 book to help with these decisions. Each method described is illustrated with one or two biologically interesting examples that have been chosen to help overcome fears of many biologists when faced with mathematical work, whilst also providing the programming code (Matlab) for each problem. Aimed primarily at students of evolutionary and behavioural ecology, this book will be of interest to any biologist interested in mathematical modelling.

Ecology --- Mathematical models --- Biological assay. --- Assay, Biological --- Bioassay --- Biology --- Mathematical models. --- Methodology --- Ecology - Mathematical models

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Le bio-essai de Hershberger est un essai de dépistage in vivo à court terme. Il permet d’évaluer la capacité d’un produit chimique à induire des activités biologiques analogues à celles induites par des agonistes et des antagonistes d’androgène ou des inhibiteurs de 5α-réductase. L’essai actuel est fondé sur les variations de poids de cinq tissus dépendant des androgènes chez le rat mâle péri-pubertaire castré: la prostate ventrale, la vésicule séminale (plus les fluides et les glandes coagulantes), le muscle élévateur de l’anus et bulbo-caverneux, la paire de glandes de Cowper et le gland. Pour tester les androgènes ou les anti-androgènes, deux - respectivement trois - groupes de doses de la substance d’essai, plus un témoin positif et un témoin de véhicule  (négatif) sont normalement suffisants. La substance d’essai est administrée par gavage ou injection sous-cutanée, chaque jour, pendant 10 jours consécutifs. Pour tester les anti-androgènes, la substance d’essai est administrée avec un agoniste d’androgène de référence. Chaque groupe traité ou témoin comprend au moins six animaux. Les animaux sont autopsiés environ 24 heures après la dernière administration de la substance d’essai. Les tissus sont excisés et les poids frais sont déterminés. Une augmentation (pour les androgènes) ou une diminution (pour les anti-androgènes) du poids de deux des cinq tissues, statistiquement significative, indique une réponse positive dans cet essai.

Environment --- Chemistry --- Physical Sciences & Mathematics --- Analytical Chemistry --- Chemical tests and reagents --- Biological assay --- Chemical reagents --- Reagents, Chemical --- Indicators and test-papers --- Assay, Biological --- Bioassay --- Biology --- Methodology

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Biological assay. --- Indicators (Biology) --- Water --- Aquatic animals --- Pollution --- Measurement. --- Effect of water pollution on. --- -Biological assay --- -Hydrology --- Bioindicators --- Biological environmental indicators --- Biological indicators --- Ecological indicators --- Environmental indicators, Biological --- Sentinel organisms --- Ecology --- Biological monitoring --- Biological reagents --- Water quality biological assessment --- Bioassay --- Drugs --- Aquatic fauna --- Water animals --- Animals --- Aquatic organisms --- Effect of water pollution on --- -Measurement --- Standards --- -Effect of water pollution on --- Indicators (Biology). --- -Bioindicators --- Assay, Biological --- Biological assay --- Biology --- Hydrology --- Pollution&delete& --- Measurement --- Methodology

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Cytokine Bioassays: Methods and Protocols provides a comprehensive collection of classic and cutting-edge methodologies that are used to analyze and quantify cytokines and their biological activities in complex biological and clinical samples. Chapters are divided into three main categories, the first category details the immunodetection of released cytokines in tissue culture supernatants, plasma, serum, and whole blood samples by immunoassays. The second part focuses on the analysis of biologically active cytokines by bioassays using neutralizing antibodies, chemotaxis assay, cytokine-induced phagocytosis assay, proteasome activity assay, and analysis of cytokine-induced immunoglobulin class switching. Part three presents analysis of intracellular cytokines by flow cytometry, immunohistochemistry, immunofluorescence confocal microscopy, and western blotting. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cytokine Bioassays: Methods and Protocols is written by experienced, basic, and clinical researchers with hands-on knowledge of the described protocols. This book will be of interest not only to biochemists, molecular biologists and immunologists but also to physician-scientists working in the field of cytokine research.

Immunology. --- Cytokines. --- Cytokines and Growth Factors. --- Cellular immunity --- Immune response --- Immunobiology --- Life sciences --- Serology --- Regulation --- Biological Assay. --- Biosensing Techniques. --- Biosensing Technics --- Bioprobes --- Biosensors --- Electrodes, Enzyme --- Bioprobe --- Biosensing Technic --- Biosensing Technique --- Biosensor --- Electrode, Enzyme --- Enzyme Electrode --- Enzyme Electrodes --- Technic, Biosensing --- Technics, Biosensing --- Technique, Biosensing --- Techniques, Biosensing --- Wearable Electronic Devices --- Microchemistry --- Assay, Biological --- Assays, Biological --- Biologic Assay --- Biologic Assays --- Bioassay --- Assay, Biologic --- Assays, Biologic --- Bioassays --- Biological Assays --- Cytokine

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Bioassay --- 543.9 --- 543.5 --- Biological Assay. --- Biological assay --- Microbiological assay --- Assay, Microbiological --- Microbial assay --- Microbiologic Technic --- Microbiologic Technics --- Microbiologic Technique --- Microbiological Technics --- Technic, Microbiologic --- Technics, Microbiological --- Technique, Microbiologic --- Techniques, Microbiologic --- Microbiologic Techniques --- Microbiological Technic --- Microbiological Technique --- Technic, Microbiological --- Technics, Microbiologic --- Technique, Microbiological --- Techniques, Microbiological --- Assay, Biological --- Assays, Biological --- Biologic Assay --- Biologic Assays --- Assay, Biologic --- Assays, Biologic --- Bioassays --- Biological Assays --- Analysis by means of biological reactions --- Biological assay. --- Microbiological assay. --- 543.9 Analysis by means of biological reactions --- Biomolecules --- Chemistry, Analytic --- Immunoassay --- Antigens --- Immunoglobulins --- Immunology --- Immunodiagnosis --- Quantitative analysis --- Quantitative chemical analysis --- Biology --- Analysis --- Quantitative --- Methodology --- Analytische chemie --- Immunologie --- Immunoassay. --- Analysis. --- Quantitative. --- Quantitative analytical chemistry --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry