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Although associated with coronary heart disease and generalized arteriosclerosis in a large number of patients, lower extremity arterial disease (LEAD) is a disease process by itself that only one in four patients will survive more than 10 years. Approximately 10 million men and women in the United States suffer from LEAD. In Lower Extremity Arterial Disease, leaders in the fields of cardiovascular medicine, hypertension, vascular surgery, vascular radiology, and vascular physiology join forces to comprehensively review the state-of-the-art concerning atherosclerosis of the arteries of the legs and feet. The authors discuss in detail LEAD's primary symptom-claudication-an intermittent pain in the leg or foot while walking, its predisposing factors, the current diagnostic methodologies, the impressive advances in the therapeutic armamentarium, and the need to screen for co-existing coronary artery disease. Additional chapters describe cutting-edge noninvasive angiography and vascular flow studies, specific drug therapy for claudication, regression of atherosclerosis therapy, gene therapy, and drug-eluting stents for peripheral arterial disease. The authors also examine the epidemiology of LEAD, the effects of smoking and effective smoking cessation programs, its pathogenesis and its association with lipid abnormalities and hypertension, aggressive risk factor modification, and the need to measure the ankle-brachial index of every patient over 45. Authoritative and up-to-date, Lower Extremity Arterial Disease offers family physicians, cardiologists, internists, radiologists, and cardiovascular surgeons a comprehensive analysis of all aspects of LEAD, ranging from diagnostic methodologies and pharmacotherapy to aggressive risk factor modification, transcatheter therapeutics, and gene therapy.

Vascular Diseases --- Arteries --- Lower Extremity --- Leg --- Artères --- diagnosis --- therapy --- physiopathology --- Blood-vessels --- Diseases --- Maladies --- Arteries -- Diseases. --- Leg -- Blood-vessels -- Diseases. --- Diagnosis --- Extremities --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Blood Vessels --- Cardiovascular Diseases --- Body Regions --- Cardiovascular System --- Anatomy --- Surgery - General and By Type --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Diseases. --- Extremities, Lower --- Extremity, Lower --- Legs --- Limb, Lower --- Limb, Pelvic --- Lower extremities --- Lower extremity --- Lower limb --- Lower limbs --- Pelvic limb --- Pelvic limbs --- Medicine. --- Vascular surgery. --- Medicine & Public Health. --- Vascular Surgery. --- Extremities (Anatomy)

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This is the first textbook entirely dedicated to the endovascular treatment of complications related to arteriovenous accesses for hemodialysis (native fistulas and prosthetic grafts). The book addresses the anatomy of upper limb arteries and veins as well as the clinical presentation of patients and the way to perform and read a fistulogram. Many details and illustrations are provided, clarifying the subtleties in catheterization and the dilation of stenoses. From a strategic point of view, it is explained for the first time that many stenoses must either be ignored or deliberately underdilated. Many images help understand the different stages of recovery from thrombosed accesses. The number of incident dialysis patients increases by 5 % every year, which means that this is a field of growing interest. There are several annual or bi-annual meetings held by numerous national or international societies (vascularaccesssociety.com, sfav.org, vasmad.org, dialysiscontroversies.org, asdin.org).

Arteries -- Diseases. --- Arteries. --- Hypertension. --- Hemodialysis --- Arteriovenous shunts, Surgical --- Blood-vessels --- Arteriovenous Malformations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Vascular Fistula --- Diagnostic Imaging --- Pathological Conditions, Anatomical --- Catheters --- Anastomosis, Surgical --- Cardiovascular Surgical Procedures --- Renal Replacement Therapy --- Vascular Grafting --- Sorption Detoxification --- Embolism and Thrombosis --- Surgical Procedures, Minimally Invasive --- Investigative Techniques --- Diagnostic Techniques and Procedures --- Vascular Malformations --- Vascular Diseases --- Pathological Conditions, Signs and Symptoms --- Therapeutics --- Surgical Procedures, Operative --- Equipment and Supplies --- Fistula --- Diseases --- Cardiovascular Diseases --- Cardiovascular Abnormalities --- Congenital Abnormalities --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Radiography --- Radiography, Interventional --- Arteriovenous Fistula --- Thrombosis --- Renal Dialysis --- Arteriovenous Shunt, Surgical --- Diagnosis --- Methods --- Vascular Surgical Procedures --- Catheters, Indwelling --- Constriction, Pathologic --- Medicine --- Health & Biological Sciences --- Radiology, MRI, Ultrasonography & Medical Physics --- Urology & Nephrology --- Cutdown --- Interventional radiology. --- Radiology, Interventional --- Medicine. --- Radiology. --- Cardiology. --- Nephrology. --- Medicine & Public Health. --- Imaging / Radiology. --- Interventional Radiology. --- Medical radiology