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Book
Bayesian Adaptive Design for Immunotherapy and Targeted Therapy
Authors: ---
ISBN: 9811981760 9811981744 Year: 2023 Publisher: Singapore : Springer,

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Abstract

This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice.


Book
Bayesian reasoning and machine learning
Author:
ISBN: 9780521518147 0521518148 Year: 2014 Publisher: Cambridge ; New York : Cambridge University Press,

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"Machine learning methods extract value from vast data sets quickly and with modest resources. They are established tools in a wide range of industrial applications, including search engines, DNA sequencing, stock market analysis, and robot locomotion, and their use is spreading rapidly. People who know the methods have their choice of rewarding jobs. This hands-on text opens these opportunities to computer science students with modest mathematical backgrounds. It is designed for final-year undergraduates and master's students with limited background in linear algebra and calculus. Comprehensive and coherent, it develops everything from basic reasoning to advanced techniques within the framework of graphical models. Students learn more than a menu of techniques, they develop analytical and problem-solving skills that equip them for the real world. Numerous examples and exercises, both computer based and theoretical, are included in every chapter. Resources for students and instructors, including a MATLAB toolbox, are available online"-- "Vast amounts of data present amajor challenge to all thoseworking in computer science, and its many related fields, who need to process and extract value from such data. Machine learning technology is already used to help with this task in a wide range of industrial applications, including search engines, DNA sequencing, stock market analysis and robot locomotion. As its usage becomes more widespread, no student should be without the skills taught in this book. Designed for final-year undergraduate and graduate students, this gentle introduction is ideally suited to readers without a solid background in linear algebra and calculus. It covers everything from basic reasoning to advanced techniques in machine learning, and rucially enables students to construct their own models for real-world problems by teaching them what lies behind the methods. Numerous examples and exercises are included in the text. Comprehensive resources for students and instructors are available online"--

Keywords

519.22 --- 519.22 Statistical theory. Statistical models. Mathematical statistics in general --- Statistical theory. Statistical models. Mathematical statistics in general --- Machine learning. --- Bayesian statistical decision theory. --- Computers --- Computer Vision & Pattern Recognition. --- Bayesian statistical decision theory --- Machine learning --- Learning, Machine --- Artificial intelligence --- Machine theory --- Bayes' solution --- Bayesian analysis --- Statistical decision --- Machine Learning --- COMPUTERS / Computer Vision & Pattern Recognition. --- Apprentissage automatique --- Statistique bayésienne --- Artificial Intelligence --- Bayes Theorem --- Analysis, Bayesian --- Bayesian Approach --- Bayesian Analysis --- Bayesian Forecast --- Bayesian Method --- Bayesian Prediction --- Approach, Bayesian --- Approachs, Bayesian --- Bayesian Approachs --- Forecast, Bayesian --- Method, Bayesian --- Prediction, Bayesian --- Theorem, Bayes --- Computational Intelligence --- AI (Artificial Intelligence) --- Computer Reasoning --- Computer Vision Systems --- Knowledge Acquisition (Computer) --- Knowledge Representation (Computer) --- Machine Intelligence --- Acquisition, Knowledge (Computer) --- Computer Vision System --- Intelligence, Artificial --- Intelligence, Computational --- Intelligence, Machine --- Knowledge Representations (Computer) --- Reasoning, Computer --- Representation, Knowledge (Computer) --- System, Computer Vision --- Systems, Computer Vision --- Vision System, Computer --- Vision Systems, Computer --- Heuristics --- 681.3*I2 --- 681.3*I2 Artificial intelligence. AI --- Artificial intelligence. AI


Book
Bayesian Data Analysis for Animal Scientists : The Basics
Author:
ISBN: 3319542745 3319542737 9783319542737 Year: 2017 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Abstract

In this book, we provide an easy introduction to Bayesian inference using MCMC techniques, making most topics intuitively reasonable and deriving to appendixes the more complicated matters. The biologist or the agricultural researcher does not normally have a background in Bayesian statistics, having difficulties in following the technical books introducing Bayesian techniques. The difficulties arise from the way of making inferences, which is completely different in the Bayesian school, and from the difficulties in understanding complicated matters such as the MCMC numerical methods. We compare both schools, classic and Bayesian, underlying the advantages of Bayesian solutions, and proposing inferences based in relevant differences, guaranteed values, probabilities of similitude or the use of ratios. We also give a scope of complex problems that can be solved using Bayesian statistics, and we end the book explaining the difficulties associated to model choice and the use of small samples. The book has a practical orientation and uses simple models to introduce the reader in this increasingly popular school of inference.

Keywords

Life sciences. --- Agriculture. --- Biostatistics. --- Animal genetics. --- Biomathematics. --- Life Sciences. --- Veterinary Medicine/Veterinary Science. --- Mathematical and Computational Biology. --- Animal Genetics and Genomics. --- Veterinary medicine. --- Statistical methods. --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Medicine --- Animal health --- Animals --- Domestic animals --- Livestock --- Genetics --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Diseases --- Losses --- Bayesian statistical decision theory --- Markov processes --- Animal industry --- Bayes Theorem --- Data Interpretation, Statistical --- Statistics --- Data Interpretations, Statistical --- Interpretation, Statistical Data --- Statistical Data Analysis --- Statistical Data Interpretation --- Data Analysis, Statistical --- Analyses, Statistical Data --- Analysis, Statistical Data --- Data Analyses, Statistical --- Interpretations, Statistical Data --- Statistical Data Analyses --- Statistical Data Interpretations --- Analysis, Bayesian --- Bayesian Approach --- Bayesian Analysis --- Bayesian Forecast --- Bayesian Method --- Bayesian Prediction --- Approach, Bayesian --- Approachs, Bayesian --- Bayesian Approachs --- Forecast, Bayesian --- Method, Bayesian --- Prediction, Bayesian --- Theorem, Bayes --- Animal products industry --- Livestock industry --- Agricultural industries --- Analysis, Markov --- Chains, Markov --- Markoff processes --- Markov analysis --- Markov chains --- Markov models --- Models, Markov --- Processes, Markov --- Stochastic processes --- Bayes' solution --- Bayesian analysis --- Statistical decision --- Statistical methods --- analysis --- Bayesian statistical decision theory. --- Biology --- Mathematics --- Biological statistics --- Biometrics (Biology) --- Biostatistics --- Biomathematics


Book
Bayesian brain
Author:
ISBN: 1282100424 9786612100420 0262294184 143562467X 9780262294188 9781435624672 9780262042383 026204238X 9780262516013 0262516012 9781282100428 6612100427 Year: 2007 Publisher: Cambridge, Mass. MIT Press

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Abstract

Experimental and theoretical neuroscientists use Bayesian approaches to analyse the brain mechanisms of perception decision-making, and motor control.

Keywords

Brain. --- Neurons. --- Bayesian statistical decision theory. --- Brain --- Neurons --- Bayesian statistical decision theory --- Cells --- Central Nervous System --- Probability --- Nervous System --- Models, Biological --- Anatomy --- Models, Theoretical --- Statistics as Topic --- Investigative Techniques --- Health Care Evaluation Mechanisms --- Epidemiologic Methods --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Quality of Health Care --- Public Health --- Health Care Quality, Access, and Evaluation --- Environment and Public Health --- Health Care --- Bayes Theorem --- Models, Neurological --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- Nerve Cells --- Cell, Nerve --- Cells, Nerve --- Nerve Cell --- Neuron --- Model, Neurological --- Neurologic Model --- Neurological Model --- Neurological Models --- Neurologic Models --- Model, Neurologic --- Models, Neurologic --- Encephalon --- Brains --- Encephalons --- Analysis, Bayesian --- Bayesian Approach --- Bayesian Analysis --- Bayesian Forecast --- Bayesian Method --- Bayesian Prediction --- Approach, Bayesian --- Approachs, Bayesian --- Bayesian Approachs --- Forecast, Bayesian --- Method, Bayesian --- Prediction, Bayesian --- Theorem, Bayes --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Healthcare Quality, Access, and Evaluation --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Public --- Quality of Care --- Quality of Healthcare --- Care Qualities --- Care Quality --- Health Care Quality --- Healthcare Quality --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Epidemiology --- Area Analysis --- Correlation Studies --- Correlation Study --- Correlation of Data --- Data Analysis --- Estimation Technics --- Estimation Techniques --- Indirect Estimation Technics --- Indirect Estimation Techniques --- Multiple Classification Analysis --- Service Statistics --- Statistical Study --- Statistics, Service --- Tables and Charts as Topic --- Analyses, Area --- Analyses, Data --- Analyses, Multiple Classification --- Analysis, Area --- Analysis, Data --- Analysis, Multiple Classification --- Area Analyses --- Classification Analyses, Multiple --- Classification Analysis, Multiple --- Data Analyses --- Data Correlation --- Data Correlations --- Estimation Technic --- Estimation Technic, Indirect --- Estimation Technics, Indirect --- Estimation Technique --- Estimation Technique, Indirect --- Estimation Techniques, Indirect --- Indirect Estimation Technic --- Indirect Estimation Technique --- Multiple Classification Analyses --- Statistical Studies --- Studies, Correlation --- Studies, Statistical --- Study, Correlation --- Study, Statistical --- Technic, Estimation --- Technic, Indirect Estimation --- Technics, Estimation --- Technics, Indirect Estimation --- Technique, Estimation --- Technique, Indirect Estimation --- Techniques, Estimation --- Techniques, Indirect Estimation --- Healthcare Evaluation Mechanisms --- Evaluation Mechanism, Healthcare --- Evaluation Mechanisms, Healthcare --- Healthcare Evaluation Mechanism --- Mechanism, Healthcare Evaluation --- Mechanisms, Healthcare Evaluation --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Models, Mathematical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Anatomies --- Biological Model --- Biological Models --- Model, Biological --- Models, Biologic --- Biologic Model --- Biologic Models --- Model, Biologic --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Probabilities --- Cerebrospinal Axis --- Axi, Cerebrospinal --- Axis, Cerebrospinal --- Central Nervous Systems --- Cerebrospinal Axi --- Nervous System, Central --- Nervous Systems, Central --- System, Central Nervous --- Systems, Central Nervous --- Cell --- Bayes' solution --- Bayesian analysis --- Nerve cells --- Neurocytes --- Cerebrum --- Mind --- methods --- Community Health --- Health, Community --- Preventive Medicine --- Education, Public Health Professional --- Pharmacy Audit --- Audit, Pharmacy --- Pharmacy Audits --- Computer Simulation --- Systems Theory --- Cell Biology --- Statistical decision --- Nervous system --- Central nervous system --- Head --- NEUROSCIENCE/General --- Mathematical statistics --- Physiology of nerves and sense organs

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