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Dissecting aortic aneurysms. --- Aortic dissection --- Dissecting aneurysms of the aorta --- Dissecting hematomas of the aorta --- Laennec's disease --- Shekelton's aneurysm --- Aortic aneurysms

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Aorta --- Malalties de l'aorta $2 thub --- Dissecció humana --- Dissecting aortic aneurysms. --- Aortic dissection --- Dissecting aneurysms of the aorta --- Dissecting hematomas of the aorta --- Laennec's disease --- Shekelton's aneurysm --- Aortic aneurysms --- Aneurismes aòrtics --- Aneurisma aòrtic --- Aneurismes de l'aorta --- Aneurismes --- Anatomia pràctica --- Dissecció --- Autòpsia

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As societies have aged and aortic diseases have become more prevalent, advances in diagnostic imaging and surgical techniques have brought significantly improved results for patients. In cardiovascular surgery, important questions remain to be addressed, however. "Strategy for Cardio-aortic and Aortic Surgery" was the theme of the 7th Keio University International Symposium for Life Sciences and Medicine. Meeting in Tokyo, researchers and specialists in cardiac surgery from around the world discussed crucial issues in their field. Papers from the symposium, collected in this volume, cover a broad range of topics, including recent advances in diagnostic imaging, brain protection during aortic surgery, spinal protection during thoracoabdominal aneurysm repair, treatment of type A acute aortic dissection, and stent-grafts and less-invasive aortic surgery. This unique book provides valuable information especially for aortic, cardiovascular, and thoracic surgeons.

Aortic Diseases --- Aneurysm, Dissecting. --- Aneurysm, Ruptured. --- Aorta --- Aortic Aneurysm --- Spinal Cord Injuries --- Ruptured Aneurysm --- Aneurysms, Ruptured --- Ruptured Aneurysms --- Dissecting Aneurysm --- Aneurysms, Dissecting --- Dissecting Aneurysms --- surgery. --- prevention & control. --- Blood Vessel Dissection --- Dissection, Blood Vessel --- Aortic Dissection --- Aortic Dissections --- Dissection, Aortic --- Dissections, Aortic --- Vascular surgery. --- Cardiac surgery. --- Vascular Surgery. --- Cardiac Surgery. --- Cardiac surgery --- Heart --- Open-heart surgery --- Vascular surgery --- Diseases --- Surgery --- Aneurysm, Dissecting --- Aneurysm, Ruptured --- surgery --- prevention & control --- Aortic Dissecting Aneurysm --- Dissecting Aneurysm Aorta --- Aneurysm Aorta, Dissecting --- Aneurysm, Aortic Dissecting --- Aorta, Dissecting Aneurysm --- Aortic Dissecting Aneurysms --- Dissecting Aneurysm Aortas --- Dissecting Aneurysm, Aortic

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In the first contribution, Morbiducci and co-workers discuss the theoretical and methodological bases supporting the Lagrangian- and Euler-based methods, highlighting their application to cardiovascular flows. The second contribution, by the Ansón and van Lenthe groups, proposes an automated virtual bench test for evaluating the stability of custom shoulder implants without the necessity of mechanical testing. Urdeitx and Doweidar, in the third paper, also adopt the finite element method for developing a computational model aim to study cardiac cell behavior under mechano-electric stimulation. In the fourth contribution, Ayensa-Jiménez et al. develop a methodology to approximate the multidimensional probability density function of the parametric analysis obtained developing a mathematical model of the cancer evolution. The fifth paper is oriented to the topological data analysis; the group of Cueto and Chinesta designs a predictive model capable of estimating the state of drivers using the data collected from motion sensors. In the sixth contribution, the Ohayon and Finet group uses wall shear stress-derived descriptors to study the role of recirculation in the arterial restenosis due to different malapposed and overlapping stent conditions. In the seventh contribution, the research group of Antón demonstrates that the simulation time can be reduced for cardiovascular numerical analysis considering an adequate geometry-reduction strategy applicable to truncated patient specific artery. In the eighth paper, Grasa and Calvo present a numerical model based on the finite element method for simulating extraocular muscle dynamics. The ninth paper, authored by Kahla et al., presents a mathematical mechano-pharmaco-biological model for bone remodeling. Martínez, Peña, and co-workers propose in the tenth paper a methodology to calibrate the dissection properties of aorta layer, with the aim of providing useful information for reliable numerical tools. In the eleventh contribution, Martínez-Bocanegra et al. present the structural behavior of a foot model using a detailed finite element model. The twelfth contribution is centered on the methodology to perform a finite, element-based, numerical model of a hydroxyapatite 3D printed bone scaffold. In the thirteenth paper, Talygin and Gorodkov present analytical expressions describing swirling jets for cardiovascular applications. In the fourteenth contribution, Schenkel and Halliday propose a novel non-Newtonian particle transport model for red blood cells. Finally, Zurita et al. propose a parametric numerical tool for analyzing a silicone customized 3D printable trachea-bronchial prosthesis.

finite element analysis --- shoulder implant stability --- implant design --- reverse shoulder arthroplasty --- micromotion --- in-silico --- 3D model --- cardiac cell --- cardiac muscle tissue --- cardiomyocyte --- electrical stimulation --- copulas --- design of experiments --- glioblastoma multiforme --- mathematical modelling --- Morse theory --- topological data analysis --- machine learning --- time series --- smart driving --- fixed points --- manifolds --- divergence --- hemodynamics --- computational fluid dynamics --- overlap --- malapposition --- stent --- stenosis --- thrombosis --- radioembolization --- liver cancer --- hepatic artery --- computational cost analysis --- personalized medicine --- patient specific --- finite element method --- implicit FEM --- explicit FEM --- skeletal muscle --- biomechanics --- mathematical model --- cell dynamics --- bone physiology --- bone disorders --- aortic dissection --- delamination tests --- cohesive zone model --- porcine aorta --- vascular mechanics --- foot finite element method --- foot and ankle model --- shared nodes --- separated mesh --- plantar pressure --- finite element modelling --- bone tissue engineering --- 3D scaffold --- additive manufacturing --- potential swirling flow --- Navier–Stokes equations --- unsteady swirling flow --- tornado-like jets --- haemorheology --- blood flow modelling --- particle transport --- numerical fluid mechanics --- tracheobronchial stent --- parametric model --- 3D printing --- customized prosthesis

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Cerebrovascular Disorders --- Arteries --- Cerebrovascular Trauma --- Aneurysm, Dissecting --- Biological Science Disciplines --- Vascular Diseases --- Trauma, Nervous System --- Blood Vessels --- Brain Diseases --- Aneurysm --- Natural Science Disciplines --- Wounds and Injuries --- Cardiovascular Diseases --- Nervous System Diseases --- Central Nervous System Diseases --- Disciplines and Occupations --- Cardiovascular System --- Diseases --- Anatomy --- Carotid Arteries --- Carotid Artery Injuries --- Vertebral Artery Dissection --- Vertebral Artery --- Carotid Artery Diseases --- Physiology --- Surgery & Anesthesiology --- Health & Biological Sciences --- Surgery - General and By Type --- Injuries and Wounds --- Injuries, Wounds --- Research-Related Injuries --- Wounds --- Wounds and Injury --- Wounds, Injury --- Injuries --- Trauma --- Injuries, Research-Related --- Injury --- Injury and Wounds --- Injury, Research-Related --- Research Related Injuries --- Research-Related Injury --- Traumas --- Wound --- First Aid --- Traumatology --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Fusiform Aneurysm --- Saccular Aneurysm --- Aneurysm, Fusiform --- Aneurysms --- Aneurysms, Fusiform --- Fusiform Aneurysms --- Brain Disorders --- CNS Disorders, Intracranial --- Central Nervous System Disorders, Intracranial --- Central Nervous System Intracranial Disorders --- Encephalon Diseases --- Encephalopathy --- Intracranial CNS Disorders --- Intracranial Central Nervous System Disorders --- Brain Disease --- Brain Disorder --- CNS Disorder, Intracranial --- Encephalon Disease --- Encephalopathies --- Intracranial CNS Disorder --- Blood Vessel --- Vessel, Blood --- Vessels, Blood --- Axonotmesis --- Injuries, Nervous System --- Neurotmesis --- Craniocervical Injuries --- Nervous System Injuries --- Axonotmeses --- Craniocervical Injury --- Nervous System Injury --- Nervous System Trauma --- Nervous System Traumas --- Neurotmeses --- Nervous System --- Disease, Vascular --- Diseases, Vascular --- Vascular Disease --- Cardiology --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Aortic Dissection --- Blood Vessel Dissection --- Dissection, Blood Vessel --- Dissecting Aneurysm --- Aneurysms, Dissecting --- Aortic Dissections --- Dissecting Aneurysms --- Dissection, Aortic --- Dissections, Aortic --- Brain Injury, Vascular --- Injury, Vascular, Brain --- Vascular Trauma, Brain --- Vascular Injury, Brain --- Brain Injuries, Vascular --- Brain Vascular Injury --- Brain Vascular Trauma --- Injuries, Brain Vascular --- Injury, Brain Vascular --- Trauma, Cerebrovascular --- Vascular Brain Injuries --- Vascular Brain Injury --- Vascular Traumas, Brain --- Artery --- Cerebrovascular Diseases --- Cerebrovascular Insufficiency --- Cerebrovascular Occlusion --- Brain Vascular Disorders --- Intracranial Vascular Disorders --- Vascular Diseases, Intracranial --- Brain Vascular Disorder --- Cerebrovascular Disease --- Cerebrovascular Disorder --- Cerebrovascular Insufficiencies --- Cerebrovascular Occlusions --- Disease, Cerebrovascular --- Diseases, Cerebrovascular --- Insufficiencies, Cerebrovascular --- Insufficiency, Cerebrovascular --- Intracranial Vascular Disease --- Intracranial Vascular Diseases --- Intracranial Vascular Disorder --- Occlusion, Cerebrovascular --- Occlusions, Cerebrovascular --- Vascular Disease, Intracranial --- Vascular Disorder, Brain --- Vascular Disorder, Intracranial --- Vascular Disorders, Brain --- Vascular Disorders, Intracranial --- Circulatory System --- Cardiovascular Systems --- Circulatory Systems --- Blood Circulation --- CNS Diseases --- Central Nervous System Disorders --- CNS Disease --- Central Nervous System Disease --- Central Nervous System Disorder --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Neurology --- Cardiovascular Disease --- Disease, Cardiovascular --- Diseases, Cardiovascular --- Arterial Diseases, Carotid --- Arterial Diseases, Common Carotid --- Arterial Diseases, External Carotid --- Arterial Diseases, Internal Carotid --- Atherosclerotic Disease, Carotid --- Carotid Artery Disorders --- Carotid Atherosclerotic Disease --- Common Carotid Artery Diseases --- External Carotid Artery Diseases --- Internal Carotid Artery Diseases --- Carotid Atherosclerosis --- Arterial Disease, Carotid --- Artery Disease, Carotid --- Artery Diseases, Carotid --- Artery Disorder, Carotid --- Artery Disorders, Carotid --- Atherosclerotic Diseases, Carotid --- Carotid Arterial Disease --- Carotid Arterial Diseases --- Carotid Artery Disease --- Carotid Artery Disorder --- Carotid Atheroscleroses --- Carotid Atherosclerotic Diseases --- Disorders, Carotid Artery --- Plaque, Atherosclerotic --- Vertebral Arteries --- Arteries, Vertebral --- Artery, Vertebral --- Spontaneous Vertebral Artery Dissection --- Traumatic Vertebral Artery Dissection --- Vertebral Artery Dissection, Spontaneous --- Vertebral Artery Dissection, Traumatic --- Dissecting Vertebral Artery Aneurysm --- Artery Dissection, Vertebral --- Artery Dissections, Vertebral --- Dissection, Vertebral Artery --- Dissections, Vertebral Artery --- Vertebral Artery Dissections --- Carotid Arteriopathies, Traumatic --- Carotid False Aneurysm --- False Aneurysm, Carotid --- Injuries, Carotid Artery --- Carotid Pseudoaneurysm --- Trauma, Carotid Artery --- Artery Injuries, Carotid --- Artery Injury, Carotid --- Artery Trauma, Carotid --- Carotid Arteriopathy, Traumatic --- Carotid Artery Injury --- Carotid Artery Trauma --- Carotid False Aneurysms --- Injury, Carotid Artery --- Pseudoaneurysm, Carotid --- Traumatic Carotid Arteriopathy --- Carotid Artery, External --- Carotid Artery, Internal --- Carotid Artery, Common --- Arteries, Carotid --- Artery, Carotid --- Carotid Artery --- Anatomies --- injuries --- Carotid artery --- Surgery.