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We now find ourselves utilizing luciferase - luciferin proteins, ATP, genes and the whole complex of these interactions to observe and follow the progress or inhibition of tumors in animal models by measuring bioluminescence intensity, spatially and temporally using highly sophisticated camera systems. This book describes applications in preclinical oncology research by bioluminescence imaging (BLI) with a variety of applications. Chapters describe current methodologies for rapid detection of contaminants using the Milliflex system, and the use of bioluminescence resonance energy transfer (BRET) technology for monitoring physical interactions between proteins in living cells. Others are using bioluminescent proteins for high sensitive optical reporters imaging in living animals, developing pH-tolerant luciferase for brighter in vivo imaging, and oscillation characteristics in bacterial bioluminescence. The book also contains descriptions of the long-term seasonal characteristics of oceanic bioluminescence and the responsible planktonic species producing bioluminescence. Such studies are few and rare.

Bioluminescence. --- Animal light --- Animal luminescence --- Light production in organisms --- Luminescence --- Photobiology --- Botany & plant sciences

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This book, written by a distinguished scientist in the field, provides a comprehensive overview of the biochemical aspects of all luminous organisms currently known. It is the first and only book that provides chemical information on all known bioluminescence systems, in a single volume. Some 35 different types of bioluminescence organisms are discussed in 10 chapters. The descriptions include: a history of the discovery of luminescence substances such as luciferins, luciferases and photoproteins; the process of research, explaining how luminescent substances have been isolated and purified; t

Bioluminescence. --- Chemiluminescence. --- Chemoluminescence --- Luminescence --- Animal light --- Animal luminescence --- Light production in organisms --- Photobiology

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Naturalists in antiquity worked hard to dispel fanciful ideas about the meaning of living lights, but remained bewildered by them. Even Charles Darwin was perplexed by the chaotic diversity of luminous organisms, which he found difficult to reconcile with his evolutionary theory. It fell to naturalists and scientists to make sense of the dazzling displays of fireflies and other organisms. In Luminous Creatures Michel Anctil shows how mythical perceptions of bioluminescence gradually gave way to a scientific understanding of its mechanisms, functions, and evolution, and to the recognition of its usefulness for biomedical and other applied fields. Following the rise of the modern scientific method and the circumnavigations and oceanographic expeditions of the eighteenth and nineteenth centuries, biologists began to realize the diversity of bioluminescence's expressions in light organs and ecological imprints, and how widespread it is on the planet. By the end of the nineteenth century an understanding of the chemical nature and physiological control of the phenomenon was at hand. Technological developments led to an explosion of knowledge on the ecology, evolution, and molecular biology of bioluminescence. Luminous Creatures tracks these historical events and illuminates the lives and the trail-blazing accomplishments of the scientists involved. It offers a unique window into the awe-inspiring, phantasmagorical world of light-producing organisms, viewed from the perspectives of casual observers and scientists alike.

Bioluminescence. --- Animal light --- Animal luminescence --- Light production in organisms --- Luminescence --- Photobiology --- General microbiology --- General biochemistry --- Hydrobiology

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This book is an authoritative monograph on the recent progresses in the chemistry of bioluminescence. It provides a comprehensive overview of the past and the latest developments in understanding the biochemical mechanisms of some 35 different types of luminous organisms, together with information helpful to students and researchers in an Appendix. It is the first and only book that provides chemical information on all currently known bioluminescence systems. Dr Shimomura is the leading practitioner in the field for the past half century, and is best known for his discovery of the jellyfish photoprotein aequorin and the green fluorescent protein. This book is the bible of bioluminescence, and is "a must read", not only for the students who study bioluminescence but also for those who work in various aspects relating to bioluminescence. This book will be an important source of chemical knowledge on bioluminescence for a long period of time in future. Fully revised since its publication in 2006, it now incorporates the most recent advances in the subject area. A new section on "Green Fluorescent Protein" has been added at the end of Chapter 4. It also contains an extensive reference section.

Luminescence --- Luminescent Proteins --- chemistry --- Bioluminescence. --- Chemiluminescence. --- chemistry. --- Chemoluminescence --- Animal light --- Animal luminescence --- Light production in organisms --- Photobiology --- Luminescence.

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This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Chemistry. --- Microbiology. --- Applied Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Physical sciences --- Biotechnology. --- Bioluminescence. --- Animal light --- Animal luminescence --- Light production in organisms --- Luminescence --- Photobiology --- Chemical engineering --- Genetic engineering