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The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, and more. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Originally published by Bentham and now distributed by Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews ha

Neovascularization inhibitors. --- Angiogenesis inhibitors --- Tumor angiogenesis inhibitors --- Antineoplastic agents

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Angiogenesis plays rate limiting roles in tumor growth and invasion. Angiogenesis inhibition has been proposed as a general strategy to fight against cancers. This book covers different therapeutic targets for angiogenesis interventions with emphasis on clinical development of antiangiogenic drugs that target antiangiogenic cascade in different forms of cancers like breast cancer, multiple myeloma, renal carcinoma, gastrointestinal, prostate and lung cancer.

Neovascularization inhibitors. --- Cancer --- Angiogenesis Inhibitors. --- Treatment.

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Angiogenesis inhibitors --- Neovascularization, pathologic --- Neovascularization, physiologic --- Angiogenesis inhibitors --- Neovascularization, pathologic --- Neovascularization, physiologic

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Angiogenesis is an extension process of the cardiovascular network within human body. It is usually triggered by the demand of oxygen and nutrients from the fast growing tissue and uncontrollably dividing cells, as seen during wound healing and tumor progression. This book focuses on tumor angiogenesis and includes 8 chapters written by highly experienced scholars from five different countries. It is the goal of this book to provide readers with an update on the molecular and cellular mechanisms of this biological process and hopefully to point out some new research directions for future therapeutic adventure.

Tumors --- Neovascularization inhibitors. --- Blood-vessels. --- Cancer --- Angiogenesis inhibitors --- Tumor angiogenesis inhibitors --- Antineoplastic agents --- Blood-vessels --- Cardiovascular medicine

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Vascular endothelial growth factors. --- Neovascularization inhibitors. --- Angiogenesis inhibitors --- Tumor angiogenesis inhibitors --- Antineoplastic agents --- Angiogenic factors --- Angiogenic proteins --- Endothelial growth factors, Vascular --- VEGFs (Proteins) --- Growth factors