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This medical dissertation by Erik Hilborn explores the role of androgen receptors and 17β dehydrogenase enzymes in breast cancer and their impact on tamoxifen treatment. Breast cancer is predominantly estrogen receptor-positive, with treatment strategies tailored to specific subtypes. This work investigates biomarkers for prognosis and assesses the influence of steroid hormones on cancer progression. It highlights the variance in androgen receptor roles across cancer subtypes and examines the modulation of 17β dehydrogenase enzymes, proposing alternative therapeutic approaches. Aimed at medical researchers and professionals, the dissertation seeks to enhance understanding of treatment resistance and improve clinical outcomes.
Tamoxifen. --- Androgens.
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Androgens --- Androgens --- Hirsutism. --- Women. --- Adverse effects. --- Physiology.
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Androgens --- Hirsutism --- Women's Health --- Androgens. --- Hypertrichosis.
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Androgens --- Gonadotropins --- Testis --- physiology
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ANDROGENS --- HIRSUTISM --- METABOLISM --- METABOLISM --- ANDROGENS --- HIRSUTISM --- METABOLISM --- METABOLISM
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