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Amino acid sequence. --- Proteins --- Protein folding. --- Conformation. --- Chemical warfare. --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Folding of proteins --- Protein conformation --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Amino acids --- Sequence alignment (Bioinformatics) --- Folding --- Conformation --- Analysis

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Computerised sequence analysis is an integral part of biotechnological research, yet many biologists have received no formal training in this important technology. Sequence Analysis Primer offers the beginner the necessary background to enter this vital field and helps more seasoned researchers to fine-tune their approach. It covers basic data manipulation such as homology searches, stem-loop identification, and protein secondary structure prediction, and is compatible with most sequence analysis programs. A detailed example giving steps for characterising a new gene sequence provides users with hands-on experience when combined with their current software.

Nucleotide sequence --- Amino acid sequence --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Amino acids --- Proteins --- Sequence alignment (Bioinformatics) --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Sequence, Nucleotide --- Nucleic acids --- Nucleotides --- Methodology. --- Analysis --- Base Sequence. --- Nucleotide sequence.

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Protein Physics is a lively presentation of the most general problems of protein structure, folding and function from the physics and chemistry perspective, based on lectures given by the authors. It deals with fibrous, membrane and, most of all, with the best studied water-soluble globular proteins, in both their native and denatured states. The major aspects of protein physics are covered systematically, physico-chemical properties of polypeptide chains; their secondary structures; tertiary structures of proteins and their classification; conformational transitions in protein molecules and t

Amino acid sequence. --- Protein binding. --- Protein folding. --- Proteins - Structure. --- Proteins. --- Proteins --- Protein binding --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Structure --- Conformation. --- Chemistry. --- Proteids --- Folding of proteins --- Protein conformation --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Folding --- Biomolecules --- Polypeptides --- Proteomics --- Amino acids --- Sequence alignment (Bioinformatics) --- Conformation --- Analysis --- Protéines --- Structure. --- Fixation --- ELSEVIER-B EPUB-LIV-FT

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Sequencing of proteins and peptides

Analytical biochemistry --- Amino acid sequence. --- Peptides --- Proteins --- Analysis. --- Aminozuursequenties. --- Analyse. --- Eiwitten. --- Amino acid sequence --- Amino Acid Sequence --- Amino Acid Sequences --- Sequence, Amino Acid --- Sequences, Amino Acid --- Protein Structure, Primary --- Primary Protein Structure --- Primary Protein Structures --- Protein Structures, Primary --- Structure, Primary Protein --- Structures, Primary Protein --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Amino acids --- Sequence alignment (Bioinformatics) --- Analysis --- analysis

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Christopher Schirwitz's thesis focuses on improving the quality of in situ synthesized high-complexity peptide micro arrays. Micro arrays containing proteins or small protein fragments in the form of peptides have become of great interest in proteomic research. With the help of these microarrays a large number of potential target molecules can be screened for interaction with a probe in a short timeframe. However, protein and peptide micro arrays are still lagging behind oligonucleotide arrays in terms of density, quality and manufacturing costs. A new approach developed at the German Cancer Research Center (DKFZ) has improved the synthesis of high-density peptide arrays. The current technology is capable of producing arrays with up to 40,000 different peptides per square cm by means of micro particle-based solid phase peptide synthesis. However, in situ synthesis approaches bear a conceptual disadvantage: The quality of the peptides is dependent on the efficiency of the synthesis so that peptide fragments are present in the resulting array among the desired full-length peptides. In peptide-protein interaction studies such peptide fragments. The central achievement of this thesis is the development of a new method allowing for the fast one-step purification of entire arrays without loss of resolution or spatial information. Christopher Schirwitz's work has resulted in a number of publications in high ranking journals.

Chemistry --- Physical Sciences & Mathematics --- Organic Chemistry --- Peptides --- Amino acid sequence. --- Purification. --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Chemistry. --- Bioorganic chemistry. --- Physical chemistry. --- Proteins. --- Bioorganic Chemistry. --- Protein Science. --- Physical Chemistry. --- Amino acids --- Proteins --- Sequence alignment (Bioinformatics) --- Organic compounds --- Analysis --- Biochemistry. --- Chemistry, Physical organic. --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Bio-organic chemistry --- Biological organic chemistry --- Biochemistry --- Composition --- Proteins . --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Synthesis. --- Analysis.