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This doctoral dissertation by Johanna Huoman explores immune maturation and modulation in childhood allergies, focusing on epigenetic, mucosal, and systemic immune mediators. The research investigates how environmental and microbial exposures affect the development of allergies and the immune system's balance between Th2, Th1, and Treg responses. The study includes analysis of chemokine levels and their association with allergy development, as well as the impact of perinatal treatments with Lactobacillus reuteri and omega-3 fatty acids on DNA methylation in immune cells. The work aims to understand the mechanisms behind allergy prevention and immune modulation in children with a high risk of developing allergic diseases. The intended audience includes researchers and professionals in medical and health sciences, particularly those specializing in immunology and allergy.
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This convenient reference provides clinicians with point-of-care guidance on the assessment and treatment of pediatric allergies in children of all ages, from infants to young adults.
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This dissertation by Sara Tomić investigates the environmental and immunological factors associated with allergic diseases in children. The study focuses on the differences in microbial exposure between children from Sweden, a country with high allergy prevalence, and Estonia, a country with low prevalence. It examines the development of immune responses, particularly mucosal and humoral immunity, and their relationship with allergic conditions like eczema and food allergies. The research highlights the role of reduced microbial exposure in affluent countries in increasing the risk of allergic diseases and emphasizes the importance of early immune development in allergy prevention.
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Food allergy. --- Food allergy --- Food allergy in children. --- Food allergy in children --- Allergy in children --- Allergy
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Hypersensitivity --- Allergy in children --- Allergie chez l'enfant --- Child --- Child.
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Hypersensitivity --- Allergy in children --- Allergie chez l'enfant --- Child.
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Food allergy in children --- Anaphylaxis --- Treatment --- Government policy
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