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This Special Issue of Marine Drugs, entitled “Bioactive Marine Heterocyclic Compounds”, aimed to collect excellent original research articles and reviews focused on the isolation of new heterocyclic marine natural products, total synthesis, synthetic modification, or on finding important bioactivities of known heterocyclic marine natural products. As a result, five original papers on isolation and one synthetic study of metabolites from marine-derived bioorganisms or a marine sponge, along with one review paper on thiazole-based peptides, were published. I am proud to show these most recent works of outstanding scientists in this field and hope this Special issue will affect new drug developments or innovation in the future.

Medicine --- altercrasins --- Alternaria sp. --- Anthocidaris crassispina --- decalin derivatives --- cytotoxicity --- mangrove plant --- endophytic fungus --- Cladosporium cladosporioides --- polyketides --- antimicrobial activity --- acetylcholinesterase --- enzymatic inhibitory activity --- genome sequencing --- gene disruption --- lobophorin --- metabolic engineering --- genome mining --- solid-state fermentation --- solid-state extraction --- Chrysosporium lobatum --- marine fungi --- phenalenone derivatives --- antibiotics --- natural product --- P. gingivalis --- methicillin-resistant S. aureus --- azole-based peptide --- marine sponge --- peptide synthesis --- cyanobacteria --- thiazole --- bioactivity --- agesasines --- bromopyrrole alkaloid --- Agelas --- altercrasins --- Alternaria sp. --- Anthocidaris crassispina --- decalin derivatives --- cytotoxicity --- mangrove plant --- endophytic fungus --- Cladosporium cladosporioides --- polyketides --- antimicrobial activity --- acetylcholinesterase --- enzymatic inhibitory activity --- genome sequencing --- gene disruption --- lobophorin --- metabolic engineering --- genome mining --- solid-state fermentation --- solid-state extraction --- Chrysosporium lobatum --- marine fungi --- phenalenone derivatives --- antibiotics --- natural product --- P. gingivalis --- methicillin-resistant S. aureus --- azole-based peptide --- marine sponge --- peptide synthesis --- cyanobacteria --- thiazole --- bioactivity --- agesasines --- bromopyrrole alkaloid --- Agelas

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This Special Issue of Marine Drugs, entitled “Bioactive Marine Heterocyclic Compounds”, aimed to collect excellent original research articles and reviews focused on the isolation of new heterocyclic marine natural products, total synthesis, synthetic modification, or on finding important bioactivities of known heterocyclic marine natural products. As a result, five original papers on isolation and one synthetic study of metabolites from marine-derived bioorganisms or a marine sponge, along with one review paper on thiazole-based peptides, were published. I am proud to show these most recent works of outstanding scientists in this field and hope this Special issue will affect new drug developments or innovation in the future.

altercrasins --- Alternaria sp. --- Anthocidaris crassispina --- decalin derivatives --- cytotoxicity --- mangrove plant --- endophytic fungus --- Cladosporium cladosporioides --- polyketides --- antimicrobial activity --- acetylcholinesterase --- enzymatic inhibitory activity --- genome sequencing --- gene disruption --- lobophorin --- metabolic engineering --- genome mining --- solid-state fermentation --- solid-state extraction --- Chrysosporium lobatum --- marine fungi --- phenalenone derivatives --- antibiotics --- natural product --- P. gingivalis --- methicillin-resistant S. aureus --- azole-based peptide --- marine sponge --- peptide synthesis --- cyanobacteria --- thiazole --- bioactivity --- agesasines --- bromopyrrole alkaloid --- Agelas

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Most of the available studies on marine fungi are based on the isolation and identification of fungi from different surfaces (e.g., submerged wood, sediments, macrophytes), mostly in coastal benthic environments. However, recent evidence suggests that fungi are also present in the oceanic water column, most likely mainly associated to particles, with the genomic potential to significantly contribute to marine biogeochemical cycles. Still, we lack even basic information on the ecology of the oceanic mycobiome, precluding us from determining the ecological role of this enigmatic kingdom in our oceans. The aim of this book and Special Issue was to focus on the ecology of marine fungi. Topics include, fungal abundance, distribution, activity, and phylogenetic and/or functional diversity in coastal to open ocean environments, including seawater column and sediments, derived both from laboratory and field studies.

Research & information: general --- Biology, life sciences --- Ecological science, the Biosphere --- marine fungi --- oxygen minimum zone --- nitrous oxide --- diversity --- 15N tracer --- size-fractioned --- eastern tropical North Pacific --- metagenome --- emergency disposal of raw of sewage --- seaside air --- bioaerosol --- mold --- yeast-like fungi --- mycology --- fungal diversity --- Antarctica --- bioprospecting --- psychrophiles --- cold-adapted enzymes --- industrial applications --- blue biotechnologies --- mycobiome --- marine sponge --- Agelas --- mesophotic --- halophytes --- marine mycology --- salt marsh fungi --- worldwide distribution --- chloroform-methanol extraction --- HPLC-UV --- LC-MS/MS --- ergosterol --- pelagic fungal biomass --- fluorescence in situ hybridisation --- mycoplankton --- fungal cultures --- pelagic --- fluorescence --- novel lineages --- phylogeny --- genetic markers --- antimicrobial --- anti-cancer --- comparative genomics --- metabolites --- whole genome sequencing --- deep-sea sediments --- trophic conditions --- Ross Sea --- total extracellular enzymatic activity --- kinetics --- maximum velocity --- half-saturation constant --- marine fungi --- oxygen minimum zone --- nitrous oxide --- diversity --- 15N tracer --- size-fractioned --- eastern tropical North Pacific --- metagenome --- emergency disposal of raw of sewage --- seaside air --- bioaerosol --- mold --- yeast-like fungi --- mycology --- fungal diversity --- Antarctica --- bioprospecting --- psychrophiles --- cold-adapted enzymes --- industrial applications --- blue biotechnologies --- mycobiome --- marine sponge --- Agelas --- mesophotic --- halophytes --- marine mycology --- salt marsh fungi --- worldwide distribution --- chloroform-methanol extraction --- HPLC-UV --- LC-MS/MS --- ergosterol --- pelagic fungal biomass --- fluorescence in situ hybridisation --- mycoplankton --- fungal cultures --- pelagic --- fluorescence --- novel lineages --- phylogeny --- genetic markers --- antimicrobial --- anti-cancer --- comparative genomics --- metabolites --- whole genome sequencing --- deep-sea sediments --- trophic conditions --- Ross Sea --- total extracellular enzymatic activity --- kinetics --- maximum velocity --- half-saturation constant