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Mesenchymal stem cells. --- Mesenchymal Stem Cells --- Adipose Tissue-Derived Mesenchymal Stem Cells --- Adipose Tissue-Derived Mesenchymal Stromal Cells --- Adipose-Derived Mesenchymal Stem Cells --- Adipose-Derived Mesenchymal Stromal Cells --- Bone Marrow Mesenchymal Stem Cells --- Bone Marrow Stromal Cell --- Bone Marrow Stromal Cells --- Bone Marrow Stromal Cells, Multipotent --- Bone Marrow Stromal Stem Cells --- Mesenchymal Progenitor Cell --- Mesenchymal Progenitor Cells --- Mesenchymal Stem Cell --- Mesenchymal Stem Cells, Adipose-Derived --- Mesenchymal Stromal Cells, Multipotent --- Multipotent Bone Marrow Stromal Cells --- Multipotent Mesenchymal Stromal Cells --- Stem Cells, Mesenchymal --- Wharton Jelly Cells --- Wharton's Jelly Cells --- Mesenchymal Stromal Cells --- Adipose Derived Mesenchymal Stem Cells --- Adipose Derived Mesenchymal Stromal Cells --- Adipose Tissue Derived Mesenchymal Stem Cells --- Adipose Tissue Derived Mesenchymal Stromal Cells --- Mesenchymal Stem Cells, Adipose Derived --- Mesenchymal Stromal Cell --- Progenitor Cell, Mesenchymal --- Progenitor Cells, Mesenchymal --- Stem Cell, Mesenchymal --- Stromal Cell, Mesenchymal --- Stromal Cells, Mesenchymal --- Wharton's Jelly Cell --- Whartons Jelly Cells --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Adipose Tissue-Derived Mesenchymal Stem Cell --- Adipose-Derived Mesenchymal Stem Cell --- Bone Marrow Mesenchymal Stem Cell --- Multipotent Bone Marrow Stromal Cell --- Multipotent Mesenchymal Stromal Cell --- Adipose Derived Mesenchymal Stem Cell --- Adipose Tissue Derived Mesenchymal Stem Cell

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Stem cells --- Placenta. --- Amniotic liquid. --- Research. --- Stem Cells. --- Amniotic Fluid. --- Mesenchymal Stem Cells. --- Placenta --- Stem Cell Transplantation. --- Umbilical Cord --- cytology. --- Transplantation, Stem Cell --- Stem Cell Transplantations --- Transplantations, Stem Cell --- Stem Cells --- Adipose Tissue-Derived Mesenchymal Stem Cells --- Adipose Tissue-Derived Mesenchymal Stromal Cells --- Adipose-Derived Mesenchymal Stem Cells --- Adipose-Derived Mesenchymal Stromal Cells --- Bone Marrow Mesenchymal Stem Cells --- Bone Marrow Stromal Cell --- Bone Marrow Stromal Cells --- Bone Marrow Stromal Cells, Multipotent --- Bone Marrow Stromal Stem Cells --- Mesenchymal Progenitor Cell --- Mesenchymal Progenitor Cells --- Mesenchymal Stem Cell --- Mesenchymal Stem Cells, Adipose-Derived --- Mesenchymal Stromal Cells, Multipotent --- Multipotent Bone Marrow Stromal Cells --- Multipotent Mesenchymal Stromal Cells --- Stem Cells, Mesenchymal --- Wharton Jelly Cells --- Wharton's Jelly Cells --- Mesenchymal Stromal Cells --- Adipose Derived Mesenchymal Stem Cells --- Adipose Derived Mesenchymal Stromal Cells --- Adipose Tissue Derived Mesenchymal Stem Cells --- Adipose Tissue Derived Mesenchymal Stromal Cells --- Mesenchymal Stem Cells, Adipose Derived --- Mesenchymal Stromal Cell --- Progenitor Cell, Mesenchymal --- Progenitor Cells, Mesenchymal --- Stem Cell, Mesenchymal --- Stromal Cell, Mesenchymal --- Stromal Cells, Mesenchymal --- Wharton's Jelly Cell --- Whartons Jelly Cells --- Amniotic Fluid Index --- Amniotic Fluid Indices --- Amniotic Fluids --- Fluid Index, Amniotic --- Fluid Indices, Amniotic --- Fluid, Amniotic --- Fluids, Amniotic --- Index, Amniotic Fluid --- Indices, Amniotic Fluid --- Fetoscopy --- Colony-Forming Unit --- Colony-Forming Units --- Mother Cells --- Progenitor Cells --- Cell, Mother --- Cell, Progenitor --- Cell, Stem --- Cells, Mother --- Cells, Progenitor --- Cells, Stem --- Colony Forming Unit --- Colony Forming Units --- Mother Cell --- Progenitor Cell --- Stem Cell --- Cell Self Renewal --- Stem Cell Research --- Liquor amnii --- Body fluids --- Embryology --- Pregnancy --- Cotyledon (Anatomy) --- Uterus, Pregnant --- transplantation --- Adipose Tissue-Derived Mesenchymal Stem Cell --- Adipose-Derived Mesenchymal Stem Cell --- Bone Marrow Mesenchymal Stem Cell --- Multipotent Bone Marrow Stromal Cell --- Multipotent Mesenchymal Stromal Cell --- Adipose Derived Mesenchymal Stem Cell --- Adipose Tissue Derived Mesenchymal Stem Cell

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Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business.

Mesenchymal stem cells. --- Stem cells --- Mesenchymal Stem Cells. --- Stem Cells. --- Stem Cell Research. --- Adult Stem Cell Research --- Embryonic Stem Cell Research --- Research, Stem Cell --- Researchs, Stem Cell --- Stem Cell Researchs --- Stem Cells --- Embryo Research --- Colony-Forming Unit --- Colony-Forming Units --- Mother Cells --- Progenitor Cells --- Cell, Mother --- Cell, Progenitor --- Cell, Stem --- Cells, Mother --- Cells, Progenitor --- Cells, Stem --- Colony Forming Unit --- Colony Forming Units --- Mother Cell --- Progenitor Cell --- Stem Cell --- Cell Self Renewal --- Stem Cell Research --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Bone marrow stromal cells --- Marrow stromal cells --- MSCs (Mesenchymal stem cells) --- Stromal cells, Bone marrow --- Stromal cells, Marrow --- Multipotent stem cells --- Therapeutic use. --- Adipose Tissue-Derived Mesenchymal Stem Cells --- Adipose Tissue-Derived Mesenchymal Stromal Cells --- Adipose-Derived Mesenchymal Stem Cells --- Adipose-Derived Mesenchymal Stromal Cells --- Bone Marrow Mesenchymal Stem Cells --- Bone Marrow Stromal Cell --- Bone Marrow Stromal Cells --- Bone Marrow Stromal Cells, Multipotent --- Bone Marrow Stromal Stem Cells --- Mesenchymal Progenitor Cell --- Mesenchymal Progenitor Cells --- Mesenchymal Stem Cell --- Mesenchymal Stem Cells, Adipose-Derived --- Mesenchymal Stromal Cells, Multipotent --- Multipotent Bone Marrow Stromal Cells --- Multipotent Mesenchymal Stromal Cells --- Stem Cells, Mesenchymal --- Wharton Jelly Cells --- Wharton's Jelly Cells --- Adipose Tissue-Derived Mesenchymal Stem Cell --- Adipose-Derived Mesenchymal Stem Cell --- Bone Marrow Mesenchymal Stem Cell --- Mesenchymal Stromal Cell --- Mesenchymal Stromal Cells --- Multipotent Bone Marrow Stromal Cell --- Multipotent Mesenchymal Stromal Cell --- Adipose Derived Mesenchymal Stem Cell --- Adipose Derived Mesenchymal Stem Cells --- Adipose Derived Mesenchymal Stromal Cells --- Adipose Tissue Derived Mesenchymal Stem Cell --- Adipose Tissue Derived Mesenchymal Stem Cells --- Adipose Tissue Derived Mesenchymal Stromal Cells --- Mesenchymal Stem Cells, Adipose Derived --- Progenitor Cell, Mesenchymal --- Progenitor Cells, Mesenchymal --- Stem Cell, Mesenchymal --- Stromal Cell, Mesenchymal --- Stromal Cells, Mesenchymal --- Wharton's Jelly Cell --- Whartons Jelly Cells --- Induced pluripotent stem cells. --- Induced pluripotent stem cells --- Induced Pluripotent Stem Cells --- Mesenchymal Stem Cells --- Mesenchymal Stem Cell Transplantation

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Adipose tissue is a rich, ubiquitous, and easily accessible source for multipotent mesenchymal stromal/stem cells (MSCs), so-called adipose-derived stromal/stem cells (ASCs). Primary isolated ASCs are a heterogeneous preparation consisting of several subpopulations of stromal/stem and precursor cells. Donor-specific differences in ASC isolations and the lack of culture standardization hinder the comparison of results from different studies. Nevertheless, ASCs are already being used in different in vivo models and clinical trials to investigate their ability to improve tissue and organ regeneration. Many questions concerning their counterparts and biology in situ, their differentiation potential in vitro and in vivo, and the mechanisms of regeneration (paracrine effects, including regeneration-promoting factors and extracellular vesicles, differentiation, and immunomodulation) are not completely understood or remain unanswered. This Special Issue covers research articles investigating various adipose tissues as a source for ASC isolation, specific cultures methods to enhance proliferation or viability, and the differentiation capacity. Furthermore, other studies highlight aspects of various diseases, the immunosuppressive potential of ASCs and their derivates, or the in vivo tracking of transplanted ASCs. This edition is complemented by a review that summarizes the current knowledge of spheroid culture system methods and applications for mesenchymal stem cells.

Medicine --- lipomas --- adipose tissue --- stem cells --- adipogenesis --- osteogenesis --- mesenchymal stem cells --- T-cells --- conditioned medium --- extracellular vesicles --- TLR --- INF-γ --- adipose-derived stromal cells --- equine metabolic syndrome --- metformin --- adipose-derived stem cells --- adipocytes --- differentiation --- collagen I --- adiponectin --- integrins --- discoidin domain-containing receptor --- ageing --- subcutaneous fat --- adipose tissue-derived mesenchymal stromal/stem cells (ASCs) --- cell differentiation --- volatile organic compounds --- metabolic monitoring --- adipose-derived stromal/stem cells --- chondrogenesis --- colony forming unit-fibroblast --- fetal bovine serum --- human platelet lysate --- mesenchymal stem cell --- regenerative medicine --- human adipose-derived stem cells --- stem cell proliferation --- signaling pathway --- adipose-derived mesenchymal stem cells --- migration --- secretion --- primary cilium --- sonic hedgehog signaling --- mesenchymal stromal/stem cells --- perirenal --- fat --- characterization --- stimulation --- lipopolysaccharide --- cytokines --- cytomegalovirus --- angiogenesis --- adipose derived mesenchymal cells --- Histogel --- 3D cell culture --- spheroid culture --- biomaterials --- phenotype --- secretory potential --- ankylosing spondylitis --- systemic lupus erythematosus --- systemic sclerosis --- mesenchymal stromal cells --- breast cancer --- tumor microenvironment --- perineural invasion --- adipose derived stem cells --- valproic acid --- protein interactions --- MAPK pathway --- JAK/STAT pathway --- mesenchymal stromal cell --- tissue of origin --- prolonged culture --- epigenetic memory --- tracking --- bio imaging --- bioluminescence --- qRT-PCR --- Ataxia telangiectasia --- Atm --- lipomas --- adipose tissue --- stem cells --- adipogenesis --- osteogenesis --- mesenchymal stem cells --- T-cells --- conditioned medium --- extracellular vesicles --- TLR --- INF-γ --- adipose-derived stromal cells --- equine metabolic syndrome --- metformin --- adipose-derived stem cells --- adipocytes --- differentiation --- collagen I --- adiponectin --- integrins --- discoidin domain-containing receptor --- ageing --- subcutaneous fat --- adipose tissue-derived mesenchymal stromal/stem cells (ASCs) --- cell differentiation --- volatile organic compounds --- metabolic monitoring --- adipose-derived stromal/stem cells --- chondrogenesis --- colony forming unit-fibroblast --- fetal bovine serum --- human platelet lysate --- mesenchymal stem cell --- regenerative medicine --- human adipose-derived stem cells --- stem cell proliferation --- signaling pathway --- adipose-derived mesenchymal stem cells --- migration --- secretion --- primary cilium --- sonic hedgehog signaling --- mesenchymal stromal/stem cells --- perirenal --- fat --- characterization --- stimulation --- lipopolysaccharide --- cytokines --- cytomegalovirus --- angiogenesis --- adipose derived mesenchymal cells --- Histogel --- 3D cell culture --- spheroid culture --- biomaterials --- phenotype --- secretory potential --- ankylosing spondylitis --- systemic lupus erythematosus --- systemic sclerosis --- mesenchymal stromal cells --- breast cancer --- tumor microenvironment --- perineural invasion --- adipose derived stem cells --- valproic acid --- protein interactions --- MAPK pathway --- JAK/STAT pathway --- mesenchymal stromal cell --- tissue of origin --- prolonged culture --- epigenetic memory --- tracking --- bio imaging --- bioluminescence --- qRT-PCR --- Ataxia telangiectasia --- Atm

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Adipose tissue is a rich, ubiquitous, and easily accessible source for multipotent mesenchymal stromal/stem cells (MSCs), so-called adipose-derived stromal/stem cells (ASCs). Primary isolated ASCs are a heterogeneous preparation consisting of several subpopulations of stromal/stem and precursor cells. Donor-specific differences in ASC isolations and the lack of culture standardization hinder the comparison of results from different studies. Nevertheless, ASCs are already being used in different in vivo models and clinical trials to investigate their ability to improve tissue and organ regeneration. Many questions concerning their counterparts and biology in situ, their differentiation potential in vitro and in vivo, and the mechanisms of regeneration (paracrine effects, including regeneration-promoting factors and extracellular vesicles, differentiation, and immunomodulation) are not completely understood or remain unanswered. This Special Issue covers research articles investigating various adipose tissues as a source for ASC isolation, specific cultures methods to enhance proliferation or viability, and the differentiation capacity. Furthermore, other studies highlight aspects of various diseases, the immunosuppressive potential of ASCs and their derivates, or the in vivo tracking of transplanted ASCs. This edition is complemented by a review that summarizes the current knowledge of spheroid culture system methods and applications for mesenchymal stem cells.

lipomas --- adipose tissue --- stem cells --- adipogenesis --- osteogenesis --- mesenchymal stem cells --- T-cells --- conditioned medium --- extracellular vesicles --- TLR --- INF-γ --- adipose-derived stromal cells --- equine metabolic syndrome --- metformin --- adipose-derived stem cells --- adipocytes --- differentiation --- collagen I --- adiponectin --- integrins --- discoidin domain-containing receptor --- ageing --- subcutaneous fat --- adipose tissue-derived mesenchymal stromal/stem cells (ASCs) --- cell differentiation --- volatile organic compounds --- metabolic monitoring --- adipose-derived stromal/stem cells --- chondrogenesis --- colony forming unit-fibroblast --- fetal bovine serum --- human platelet lysate --- mesenchymal stem cell --- regenerative medicine --- human adipose-derived stem cells --- stem cell proliferation --- signaling pathway --- adipose-derived mesenchymal stem cells --- migration --- secretion --- primary cilium --- sonic hedgehog signaling --- mesenchymal stromal/stem cells --- perirenal --- fat --- characterization --- stimulation --- lipopolysaccharide --- cytokines --- cytomegalovirus --- angiogenesis --- adipose derived mesenchymal cells --- Histogel --- 3D cell culture --- spheroid culture --- biomaterials --- phenotype --- secretory potential --- ankylosing spondylitis --- systemic lupus erythematosus --- systemic sclerosis --- mesenchymal stromal cells --- breast cancer --- tumor microenvironment --- perineural invasion --- adipose derived stem cells --- valproic acid --- protein interactions --- MAPK pathway --- JAK/STAT pathway --- mesenchymal stromal cell --- tissue of origin --- prolonged culture --- epigenetic memory --- tracking --- bio imaging --- bioluminescence --- qRT-PCR --- Ataxia telangiectasia --- Atm --- n/a