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Malignant mesothelioma is an aggressive and fatal neoplasm of serous membranes. The pathogenesis of malignant mesothelioma is clearly linked to incorporated asbestos fibers. Owing to the late banning of asbestos use in industrial nations and the continuing mining and consumption of asbestos in many countries, the incidence of malignant mesothelioma is still rising worldwide. This book covers all the important aspects of the disease by bringing together contributions from selected experts in the fields of epidemiology, imaging, pathological diagnosis, therapy, genetics, and screening. Special emphasis is placed on the latest diagnostic techniques and current therapy standards. In addition, the mineralogy of asbestos is reviewed and clear advice is included on the analysis of tissue mineral fiber content. By providing a compact, scientifically based, and up-to-date overview of the management of malignant mesothelioma, this volume will be invaluable for all clinicians and pathologists who are engaged in the diagnosis and treatment of the disease or in related research.
Asbestos -- adverse effects. --- Asbestosis -- Toxicology. --- Mesothelioma -- Miscellanea. --- Mesothelioma. --- Silicates --- Neoplasms, Mesothelial --- Adenoma --- Silicic Acid --- Neoplasms, Glandular and Epithelial --- Minerals --- Neoplasms by Histologic Type --- Inorganic Chemicals --- Silicon Dioxide --- Neoplasms --- Silicon Compounds --- Chemicals and Drugs --- Diseases --- Asbestos --- Mesothelioma --- Medicine --- Health & Biological Sciences --- Oncology --- Mesothelial Neoplasms --- Mesothelial Neoplasm --- Neoplasm, Mesothelial --- Silicate --- Mesotheliomas --- Compounds, Silicon --- Benign Neoplasms --- Malignancy --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Neoplasias --- Neoplasm, Benign --- Tumor --- Aerosil --- Aerosil 380 --- Cristobalite --- Quso G-32 --- Quso G32 --- Tridymite --- Silica --- 380, Aerosil --- Dioxide, Silicon --- G32, Quso --- Quso G 32 --- Chemicals, Inorganic --- Histological Type of Neoplasm --- Histological Types of Neoplasms --- Neoplasms by Histological Type --- Neoplasm Histological Type --- Neoplasm Histological Types --- Neoplasms Histological Type --- Neoplasms Histological Types --- Epithelial Neoplasms --- Glandular Neoplasms --- Glandular and Epithelial Neoplasms --- Neoplasms, Epithelial --- Neoplasms, Glandular --- Neoplasms, Glandular Epithelial --- Epithelial Neoplasm --- Epithelial Neoplasm, Glandular --- Epithelial Neoplasms, Glandular --- Glandular Epithelial Neoplasm --- Glandular Epithelial Neoplasms --- Glandular Neoplasm --- Neoplasm, Epithelial --- Neoplasm, Glandular --- Neoplasm, Glandular Epithelial --- Adenoma, Basal Cell --- Adenoma, Follicular --- Adenoma, Microcystic --- Adenoma, Monomorphic --- Adenoma, Papillary --- Adenoma, Trabecular --- Adenomas --- Adenomas, Basal Cell --- Adenomas, Follicular --- Adenomas, Microcystic --- Adenomas, Monomorphic --- Adenomas, Papillary --- Adenomas, Trabecular --- Basal Cell Adenoma --- Basal Cell Adenomas --- Follicular Adenoma --- Follicular Adenomas --- Microcystic Adenoma --- Microcystic Adenomas --- Monomorphic Adenoma --- Monomorphic Adenomas --- Papillary Adenoma --- Papillary Adenomas --- Trabecular Adenoma --- Trabecular Adenomas --- Hydrated Silica Gel --- Silica Hydrate --- Silicate Hydrate --- Gel, Hydrated Silica --- Hydrate, Silica --- Hydrate, Silicate --- Silica Gel, Hydrated --- Medicine. --- Oncology. --- Medicine & Public Health. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Diagnosis. --- Treatment. --- Mesothelium --- Oncology .
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Pituitary gland --- Tumors. --- Pituitary Neoplasms --- Pituitary Hormones --- Hormones, Pituitary --- Cancer of Pituitary --- Cancer of the Pituitary --- Pituitary Adenoma --- Pituitary Carcinoma --- Pituitary Tumors --- Pituitary Cancer --- Adenoma, Pituitary --- Adenomas, Pituitary --- Cancer, Pituitary --- Cancers, Pituitary --- Carcinoma, Pituitary --- Carcinomas, Pituitary --- Neoplasm, Pituitary --- Neoplasms, Pituitary --- Pituitary Adenomas --- Pituitary Cancers --- Pituitary Carcinomas --- Pituitary Neoplasm --- Pituitary Tumor --- Tumor, Pituitary --- Tumors, Pituitary --- Adenoma, Basophil --- Adenoma, Chromophobe --- Adenoma, Acidophil --- Pituitary Gland
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Pituitary Neoplasms. --- Cancer of Pituitary --- Cancer of the Pituitary --- Pituitary Adenoma --- Pituitary Carcinoma --- Pituitary Tumors --- Pituitary Cancer --- Adenoma, Pituitary --- Adenomas, Pituitary --- Cancer, Pituitary --- Cancers, Pituitary --- Carcinoma, Pituitary --- Carcinomas, Pituitary --- Neoplasm, Pituitary --- Neoplasms, Pituitary --- Pituitary Adenomas --- Pituitary Cancers --- Pituitary Carcinomas --- Pituitary Neoplasm --- Pituitary Tumor --- Tumor, Pituitary --- Tumors, Pituitary --- Adenoma, Basophil --- Adenoma, Chromophobe --- Adenoma, Acidophil --- Pituitary gland --- Tumors.
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Pituitary Neoplasms. --- Pituitary gland --- -Hypophysis cerebri --- Pituitary body --- Brain --- Endocrine glands --- Hypothalamo-hypophyseal system --- Cancer of Pituitary --- Cancer of the Pituitary --- Pituitary Adenoma --- Pituitary Carcinoma --- Pituitary Tumors --- Pituitary Cancer --- Adenoma, Pituitary --- Adenomas, Pituitary --- Cancer, Pituitary --- Cancers, Pituitary --- Carcinoma, Pituitary --- Carcinomas, Pituitary --- Neoplasm, Pituitary --- Neoplasms, Pituitary --- Pituitary Adenomas --- Pituitary Cancers --- Pituitary Carcinomas --- Pituitary Neoplasm --- Pituitary Tumor --- Tumor, Pituitary --- Tumors, Pituitary --- Adenoma, Basophil --- Adenoma, Chromophobe --- Adenoma, Acidophil --- Tumors --- Pituitary neoplasms. --- Tumors. --- -Tumors --- Pituitary Neoplasms
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Urinary organs --- Lower Urinary Tract Symptoms --- Prostatic Hyperplasia --- Benign prostatic hyperplasia. --- Diseases. --- Benign prostatic hypertrophy --- BPH (Disease) --- Prostatic hyperplasia, Benign --- Prostatic hypertrophy, Benign --- Hyperplasia --- Prostate --- Adenoma, Prostatic --- Benign Prostatic Hyperplasia --- Prostatic Adenoma --- Prostatic Hyperplasia, Benign --- Prostatic Hypertrophy --- Prostatic Hypertrophy, Benign --- Adenomas, Prostatic --- Benign Prostatic Hypertrophy --- Hyperplasia, Prostatic --- Hypertrophy, Benign Prostatic --- Prostatic Adenomas --- Prostatic Neoplasms --- Prostatism --- Urology --- Aging --- Hypertrophy --- Lower Urinary Tract Symptom --- Lower Urinary Tract Symptoms. --- Prostatic Hyperplasia.
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Thyroid Neoplasms. --- Radiation Effects. --- Thyroid Gland --- Neoplasms, Radiation-Induced. --- Thyroid Neoplasms --- Radiation carcinogenesis --- -Thyroid gland --- -Endocrine glands --- Hypothalamic-pituitary-thyroid axis --- Radiation-induced cancer --- Radiation-induced tumors --- Tumors, Radiation-induced --- Carcinogenesis --- Radiation injuries --- Effects, Radiation --- Effect, Radiation --- Radiation Effect --- Radiation Genetics --- Radiation Tolerance --- Cancer of the Thyroid --- Neoplasms, Thyroid --- Thyroid Adenoma --- Thyroid Carcinoma --- Cancer of Thyroid --- Thyroid Cancer --- Adenoma, Thyroid --- Adenomas, Thyroid --- Cancer, Thyroid --- Cancers, Thyroid --- Carcinoma, Thyroid --- Carcinomas, Thyroid --- Neoplasm, Thyroid --- Thyroid Adenomas --- Thyroid Cancers --- Thyroid Carcinomas --- Thyroid Neoplasm --- radiation effects. --- etiology. --- Congresses --- Cancer --- -Congresses --- Thyroid gland --- Thyroid neoplasms --- Congresses. --- Radiation effects --- Etiology --- -radiation effects. --- Neoplasms, Radiation-Induced --- Radiation Effects --- Cancer, Radiation-Induced --- Radiation-Induced Neoplasms --- Radiation-Induced Cancer --- Cancer, Radiation Induced --- Cancers, Radiation-Induced --- Neoplasm, Radiation-Induced --- Neoplasms, Radiation Induced --- Radiation Induced Cancer --- Radiation Induced Neoplasms --- Radiation-Induced Cancers --- Radiation-Induced Neoplasm --- Endocrine glands --- Cancer&delete& --- radiation effects --- etiology
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Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, rendering oncology well along the path to “personalised cancer medicine”. Thanks to developments in genetics, several mutations and gene rearrangements have been identified in patients with endocrine cancers (e.g., thyroid and adrenocortical carcinoma). In particular, each patient can be considered as a unique, individual one, with unique genetic information. The aim of this Special Issue is to offer an overview of exciting new research in the area of endocrine tumours may set the stage for an innovative personalised management and precision medicine modalities for individualised care.New affordable individual genomic analyses, as well as the opportunity to test new compounds in primary cells may allow a personalised management of patients with endocrine malignancies. This approach may improve the prediction of clinical outcome and therapeutic effectiveness, as well as help to avoid the use of ineffective drugs. However, further efforts are needed to obtain an adjustment of clinical management in patients with endocrine cancers that would rely solely or in great part on genetic information. This Special Issue includes basic, translational, and clinical papers on personalised medicine in endocrine malignancies (i.e., thyroid and adrenal), especially focusing on diagnostic and prognostic biomarkers, as well as novel drug targets or targeted treatments, including eventual clinical trials.
Medicine --- papillary thyroid cancer --- SUV PET/CT --- BRAF V600E --- immune checkpoint inhibitors (ICIs) --- ipilimumab --- nivolumab --- prolactinoma --- Cushing’s disease --- aggressive pituitary tumor --- aggressive PitNET --- aggressive pituitary adenoma --- pituitary carcinoma --- adrenocortical cancer --- adrenal adenomas --- adrenal tumors --- p53 --- p27 --- ki-67 --- reticulin --- mitotane --- adjuvant treatment --- recurrence --- recurrence free survival --- timing --- intratumoral heterogeneity --- thyroid tumor --- BRAF --- RET/PTC rearrangements --- RAS mutation --- adrenal cortex --- carcinoma --- angiogenesis --- gene expression --- osteopontin --- hyaluronan synthase 1 --- multikinase inhibitors --- sorafenib --- lenvatinib --- differentiated thyroid cancer --- radioiodine resistance --- predictive marker --- predictors --- response to treatment --- survival --- information needs and preferences --- focus group interview --- personalized medicine --- neuroendocrine tumours --- phaeochromocytoma --- paraganglioma --- molecular clusters --- n/a --- Cushing's disease
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Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, rendering oncology well along the path to “personalised cancer medicine”. Thanks to developments in genetics, several mutations and gene rearrangements have been identified in patients with endocrine cancers (e.g., thyroid and adrenocortical carcinoma). In particular, each patient can be considered as a unique, individual one, with unique genetic information. The aim of this Special Issue is to offer an overview of exciting new research in the area of endocrine tumours may set the stage for an innovative personalised management and precision medicine modalities for individualised care.New affordable individual genomic analyses, as well as the opportunity to test new compounds in primary cells may allow a personalised management of patients with endocrine malignancies. This approach may improve the prediction of clinical outcome and therapeutic effectiveness, as well as help to avoid the use of ineffective drugs. However, further efforts are needed to obtain an adjustment of clinical management in patients with endocrine cancers that would rely solely or in great part on genetic information. This Special Issue includes basic, translational, and clinical papers on personalised medicine in endocrine malignancies (i.e., thyroid and adrenal), especially focusing on diagnostic and prognostic biomarkers, as well as novel drug targets or targeted treatments, including eventual clinical trials.
papillary thyroid cancer --- SUV PET/CT --- BRAF V600E --- immune checkpoint inhibitors (ICIs) --- ipilimumab --- nivolumab --- prolactinoma --- Cushing’s disease --- aggressive pituitary tumor --- aggressive PitNET --- aggressive pituitary adenoma --- pituitary carcinoma --- adrenocortical cancer --- adrenal adenomas --- adrenal tumors --- p53 --- p27 --- ki-67 --- reticulin --- mitotane --- adjuvant treatment --- recurrence --- recurrence free survival --- timing --- intratumoral heterogeneity --- thyroid tumor --- BRAF --- RET/PTC rearrangements --- RAS mutation --- adrenal cortex --- carcinoma --- angiogenesis --- gene expression --- osteopontin --- hyaluronan synthase 1 --- multikinase inhibitors --- sorafenib --- lenvatinib --- differentiated thyroid cancer --- radioiodine resistance --- predictive marker --- predictors --- response to treatment --- survival --- information needs and preferences --- focus group interview --- personalized medicine --- neuroendocrine tumours --- phaeochromocytoma --- paraganglioma --- molecular clusters --- n/a --- Cushing's disease
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Major technological advances in genomics have made it possible to identify critical genetic alterations in cancer, rendering oncology well along the path to “personalised cancer medicine”. Thanks to developments in genetics, several mutations and gene rearrangements have been identified in patients with endocrine cancers (e.g., thyroid and adrenocortical carcinoma). In particular, each patient can be considered as a unique, individual one, with unique genetic information. The aim of this Special Issue is to offer an overview of exciting new research in the area of endocrine tumours may set the stage for an innovative personalised management and precision medicine modalities for individualised care.New affordable individual genomic analyses, as well as the opportunity to test new compounds in primary cells may allow a personalised management of patients with endocrine malignancies. This approach may improve the prediction of clinical outcome and therapeutic effectiveness, as well as help to avoid the use of ineffective drugs. However, further efforts are needed to obtain an adjustment of clinical management in patients with endocrine cancers that would rely solely or in great part on genetic information. This Special Issue includes basic, translational, and clinical papers on personalised medicine in endocrine malignancies (i.e., thyroid and adrenal), especially focusing on diagnostic and prognostic biomarkers, as well as novel drug targets or targeted treatments, including eventual clinical trials.
Medicine --- papillary thyroid cancer --- SUV PET/CT --- BRAF V600E --- immune checkpoint inhibitors (ICIs) --- ipilimumab --- nivolumab --- prolactinoma --- Cushing's disease --- aggressive pituitary tumor --- aggressive PitNET --- aggressive pituitary adenoma --- pituitary carcinoma --- adrenocortical cancer --- adrenal adenomas --- adrenal tumors --- p53 --- p27 --- ki-67 --- reticulin --- mitotane --- adjuvant treatment --- recurrence --- recurrence free survival --- timing --- intratumoral heterogeneity --- thyroid tumor --- BRAF --- RET/PTC rearrangements --- RAS mutation --- adrenal cortex --- carcinoma --- angiogenesis --- gene expression --- osteopontin --- hyaluronan synthase 1 --- multikinase inhibitors --- sorafenib --- lenvatinib --- differentiated thyroid cancer --- radioiodine resistance --- predictive marker --- predictors --- response to treatment --- survival --- information needs and preferences --- focus group interview --- personalized medicine --- neuroendocrine tumours --- phaeochromocytoma --- paraganglioma --- molecular clusters
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Liver --- Liver Neoplasms --- Adenocarcinoma --- Digestive System Neoplasms --- Liver Diseases --- Carcinoma --- Neoplasms by Site --- Neoplasms, Glandular and Epithelial --- Digestive System Diseases --- Diseases --- Neoplasms by Histologic Type --- Neoplasms --- Carcinoma, Hepatocellular --- Medicine --- Health & Biological Sciences --- Oncology --- Histological Type of Neoplasm --- Histological Types of Neoplasms --- Neoplasms by Histological Type --- Neoplasm Histological Type --- Neoplasm Histological Types --- Neoplasms Histological Type --- Neoplasms Histological Types --- Liver Cancer, Adult --- Liver Cell Carcinoma --- Liver Cell Carcinoma, Adult --- Hepatocellular Carcinoma --- Hepatoma --- Adult Liver Cancer --- Adult Liver Cancers --- Cancer, Adult Liver --- Cancers, Adult Liver --- Carcinoma, Liver Cell --- Carcinomas, Hepatocellular --- Carcinomas, Liver Cell --- Cell Carcinoma, Liver --- Cell Carcinomas, Liver --- Hepatocellular Carcinomas --- Hepatomas --- Liver Cancers, Adult --- Liver Cell Carcinomas --- Benign Neoplasms --- Malignancy --- Malignant Neoplasms --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Malignant Neoplasm --- Neoplasias --- Neoplasm, Benign --- Neoplasm, Malignant --- Neoplasms, Malignant --- Tumor --- Medical Oncology --- Digestive System Disorders --- Hepatobiliary Diseases --- Hepatobiliary Disorders --- Digestive System Disease --- Digestive System Disorder --- Hepatobiliary Disease --- Hepatobiliary Disorder --- System Disorders, Digestive --- Epithelial Neoplasms --- Glandular Neoplasms --- Glandular and Epithelial Neoplasms --- Neoplasms, Epithelial --- Neoplasms, Glandular --- Neoplasms, Glandular Epithelial --- Epithelial Neoplasm --- Epithelial Neoplasm, Glandular --- Epithelial Neoplasms, Glandular --- Glandular Epithelial Neoplasm --- Glandular Epithelial Neoplasms --- Glandular Neoplasm --- Neoplasm, Epithelial --- Neoplasm, Glandular --- Neoplasm, Glandular Epithelial --- Neoplasms by Sites --- Site, Neoplasm --- Sites, Neoplasm --- Neoplasm Site --- Neoplasm Sites --- Epithelial Tumors, Malignant --- Malignant Epithelial Neoplasms --- Neoplasms, Malignant Epithelial --- Carcinoma, Anaplastic --- Carcinoma, Spindle-Cell --- Carcinoma, Undifferentiated --- Carcinomatosis --- Epithelial Neoplasms, Malignant --- Epithelioma --- Anaplastic Carcinoma --- Anaplastic Carcinomas --- Carcinoma, Spindle Cell --- Carcinomas --- Carcinomatoses --- Epithelial Neoplasm, Malignant --- Epithelial Tumor, Malignant --- Epitheliomas --- Malignant Epithelial Neoplasm --- Malignant Epithelial Tumor --- Malignant Epithelial Tumors --- Neoplasm, Malignant Epithelial --- Spindle-Cell Carcinoma --- Spindle-Cell Carcinomas --- Tumor, Malignant Epithelial --- Undifferentiated Carcinoma --- Undifferentiated Carcinomas --- Liver Dysfunction --- Disease, Liver --- Diseases, Liver --- Dysfunction, Liver --- Dysfunctions, Liver --- Liver Disease --- Liver Dysfunctions --- Cancer of the Digestive System --- Neoplasms, Digestive System --- Cancer of Digestive System --- Digestive System Cancer --- Cancer, Digestive System --- Cancers, Digestive System --- Digestive System Cancers --- Digestive System Neoplasm --- Neoplasm, Digestive System --- Adenocarcinoma, Basal Cell --- Adenocarcinoma, Granular Cell --- Adenocarcinoma, Oxyphilic --- Adenocarcinoma, Tubular --- Adenoma, Malignant --- Carcinoma, Cribriform --- Carcinoma, Granular Cell --- Carcinoma, Tubular --- Adenocarcinomas --- Adenocarcinomas, Basal Cell --- Adenocarcinomas, Granular Cell --- Adenocarcinomas, Oxyphilic --- Adenocarcinomas, Tubular --- Adenomas, Malignant --- Basal Cell Adenocarcinoma --- Basal Cell Adenocarcinomas --- Carcinomas, Cribriform --- Carcinomas, Granular Cell --- Carcinomas, Tubular --- Cribriform Carcinoma --- Cribriform Carcinomas --- Granular Cell Adenocarcinoma --- Granular Cell Adenocarcinomas --- Granular Cell Carcinoma --- Granular Cell Carcinomas --- Malignant Adenoma --- Malignant Adenomas --- Oxyphilic Adenocarcinoma --- Oxyphilic Adenocarcinomas --- Tubular Adenocarcinoma --- Tubular Adenocarcinomas --- Tubular Carcinoma --- Tubular Carcinomas --- Carcinoma, Non-Small-Cell Lung --- Cancer of the Liver --- Cancer, Hepatocellular --- Hepatic Neoplasms --- Hepatocellular Cancer --- Neoplasms, Hepatic --- Neoplasms, Liver --- Cancer of Liver --- Hepatic Cancer --- Liver Cancer --- Cancer, Hepatic --- Cancer, Liver --- Cancers, Hepatic --- Cancers, Hepatocellular --- Cancers, Liver --- Hepatic Cancers --- Hepatic Neoplasm --- Hepatocellular Cancers --- Liver Cancers --- Liver Neoplasm --- Neoplasm, Hepatic --- Neoplasm, Liver --- Hepatocellular carcinoma --- Epithelial Cell Neoplasms --- Glandular Cell Neoplasms --- Cell Neoplasm, Epithelial --- Cell Neoplasm, Glandular --- Cell Neoplasms, Epithelial --- Epithelial Cell Neoplasm --- Glandular Cell Neoplasm --- Neoplasm, Epithelial Cell --- Neoplasm, Glandular Cell --- Liver Neoplasms. --- Adenocarcinoma. --- Digestive System Neoplasms. --- Liver Diseases. --- Carcinoma. --- Neoplasms by Site. --- Neoplasms, Glandular and Epithelial. --- Digestive System Diseases. --- Disease. --- Neoplasms by Histologic Type. --- Neoplasms. --- Carcinoma, Hepatocellular. --- Cancer.
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