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This volume is a collection of chapters from the leading experts in the relatively new and burgeoning field of persister cell studies. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus of the book is on studies that provide an understanding of the mechanisms of persister formation, antibiotic tolerance and role in disease, at the molecular level.
Medical microbiology. --- Immunology. --- Infectious diseases. --- Medical Microbiology. --- Infectious Diseases. --- Immunobiology --- Life sciences --- Serology --- Malalties infeccioses --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Salut pública --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi
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This book provides a comprehensive overview of pertussis - also known as whooping cough. The first part discusses the evolution the genus Bordetellae and the molecular epidemiology of B. pertussis, while the following chapters focus on the role of B. pertussis virulence factors in infection and disease and on the mechanisms of the immune response to infection and vaccination. The book also explores the prevention and control of the disease as well as its clinical management, with the finally section addressing vaccination, from improved immunization strategies to novel vaccines. Pertussis remains one of the most poorly controlled vaccine-preventable diseases around the globe. Universal vaccination has dramatically reduced its incidence but has failed to bring it completely under control. In recent decades, changes in pertussis epidemiology have been noted, likely related to the use of acellular pertussis vaccines, which in many countries have replaced older-generation, whole-cell pertussis vaccines. Several years after their introduction, it is becoming apparent that immunity conferred by acellular vaccines wanes more rapidly than expected. Unlike whole-cell vaccines, acellular vaccines, while protecting against the disease, do not seem to prevent colonization and transmission. Increasing incidence among adolescents and adults makes them a reservoir for transmission to unimmunized infants, who in turn are at risk of severe disease and death. This book is a valuable resource for researchers and clinicians in the field of medical microbiology, vaccine research and infectious diseases.
Medical microbiology. --- Bacteriology. --- Infectious diseases. --- Medical Microbiology. --- Infectious Diseases. --- Microbiology --- Whooping cough. --- Pertussis --- Cough --- Gram-negative bacterial infections --- Respiratory infections --- Malalties infeccioses --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Salut pública --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi
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This book examines all aspects of the imaging of spinal infection. The diagnosis of spinal infection has been a challenge for many years. In addition to clinical and laboratory findings and histopathological examination, imaging has a major role in aiding and expediting the correct diagnosis. This book comprehensively addresses how imaging can help in localizing the site and specifying the extent of a variety of spinal infections. After introductory chapters on the epidemiology and pathophysiology of spinal infection, the different imaging techniques are discussed in detail. The bulk of the book addresses different specific spinal infections caused by various pathogens. These comprise chapters on hematogeneous pyogenic spondylodiscitis, iatrogenic spinal infection, pyogenic epidural abscess, spinal brucellosis, salmonella spondylodiscitis, spinal tuberculosis, spinal hydatidosis, and fungal spondylodiscitis. The last chapter describes diagnostic algorithm of spinal infection. The book is written by Tunisian, Asian and European experts and will be a valuable resource for all medical practitioners who deal with spinal infection, including radiologists, rheumatologists and orthopedic surgeons.
Radiology. --- Rheumatology. --- Imaging / Radiology. --- Internal medicine --- Connective tissues --- Joints --- Radiological physics --- Physics --- Radiation --- Diseases --- Infeccions --- Columna vertebral --- Reumatologia --- Medicina interna --- Reumatologia pediàtrica --- Malalties del teixit connectiu --- Espina dorsal --- Raquis --- Ossos --- Vèrtebres --- Infecció --- Etiologia --- Microbiologia mèdica --- Abscessos --- Artritis infecciosa --- Infeccions del tracte urinari --- Malalties transmeses per l'aigua --- Infeccions en els infants --- Infeccions nosocomials --- Infeccions oportunistes --- Infeccions respiratòries
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Infections in intensive care is a very broad topic, and this book provides concise yet comprehensive coverage. It focuses on the appropriate and judicious use of microbiological, radiological and point-of-care tests in diagnostic work-ups and evidence-based management protocols. Moreover, it offers essential information on the diagnosis and management of commonly encountered infections in the intensive care unit, making it a handy ready-reference manual for intensivists. .
Internal medicine. --- Internal Medicine. --- Medicine, Internal --- Medicine --- Infection. --- Infectious diseases --- Diseases --- Medical microbiology --- Causes and theories of causation --- Infeccions --- Medicina intensiva --- Cures intensives --- Medicina crítica --- Medicina --- Cura dels malalts terminals --- Infermeria en cures intensives --- Malalts en estat crític --- Medicina intensiva en cardiologia --- Monitoratge de pacients --- Pediatria intensiva --- Medicina d'urgència --- Infecció --- Etiologia --- Microbiologia mèdica --- Abscessos --- Artritis infecciosa --- Infeccions del tracte urinari --- Malalties transmeses per l'aigua --- Infeccions en els infants --- Infeccions nosocomials --- Infeccions oportunistes --- Infeccions respiratòries
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This book discusses the historical context, country experience, and best practices that led to eliminating infectious diseases from the WHO’s South-East Asia Region, such as malaria, lymphatic filariasis, yaws, trachoma, and mother-to-child HIV in the mid-twentieth and twenty-first century. The UN Sustainable Development Goals (3.3) targets to end AIDS, tuberculosis, malaria, and neglected tropical diseases and combat hepatitis, water-borne diseases and other communicable diseases by 2030. In this context, this book is of high significance to countries from the SEA region and around the globe. It helps create national strategies and action plans on infectious disease elimination and thus attaining SDG 3.3. This is an open access book.
Diseases. --- Human beings --- Illness --- Illnesses --- Morbidity --- Sickness --- Sicknesses --- Medicine --- Epidemiology --- Health --- Pathology --- Sick --- Diseases --- infectious diseases in South East Asia --- lymphatic filariasis --- communicable diseases --- neonatal tetanus --- elimination of Yaws --- elimination of Malaria --- polio-free regions --- UN Sustainable Development Goals --- Malalties infeccioses --- Sud-est asiàtic --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Salut pública --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi --- Àsia del sud-est --- Àsia Sud-oriental --- Sud-est d'Àsia --- Orient --- Filipines --- Indonèsia --- Indoxina --- Mekong (Àsia : Curs d'aigua) --- Singapur --- Timor Oriental --- Communicable diseases --- Health planning --- Prevention.
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Communicable Diseases. --- Infection. --- Communicable diseases --- Infection --- Maladies infectieuses --- Periodicals. --- Périodiques --- Communicable diseases. --- pharmacoeconomics --- public health --- education --- infectious disease --- Infectious diseases --- Diseases --- Medical microbiology --- Contagion and contagious diseases --- Contagious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Epidemics --- Quarantine --- Infections --- Infectious Diseases --- Communicable Disease --- Disease, Communicable --- Disease, Infectious --- Diseases, Communicable --- Diseases, Infectious --- Infectious Disease --- Disease Outbreaks --- Disease Transmission, Infectious --- Causes and theories of causation --- Communicable Diseases --- Infectious diseases. Communicable diseases --- Infection and Infestation --- Infections and Infestations --- Infestation and Infection --- Infestations and Infections --- besmettelijke ziekten --- Infections. --- infectious diseases --- epidemiology --- Infeccions. --- Malalties infeccioses. --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Salut pública --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi --- Infecció --- Etiologia --- Artritis infecciosa --- Infeccions del tracte urinari --- Malalties transmeses per l'aigua --- Infeccions en els infants --- Infeccions nosocomials --- Infeccions oportunistes --- Infeccions respiratòries
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This volume focuses on Global Catastrophic Biological Risks (GCBRs), a special class of infectious disease outbreaks or pandemics in which the combined capacity of the world’s private and government resources becomes severely strained. These events, of which the 1918 influenza pandemic is emblematic, cause severe disruptions in the normal functioning of the world, exact heavy tolls in terms of morbidity and mortality, and lead to major economic losses. GCBRs can be caused by any type of microorganism, and myriad contextual factors can influence their impact. Additionally, there are cascading questions that arise in connection with GCBR prediction, preparation, and response. This book gathers contributions from thought leaders who discuss the multi-faceted approaches needed in order to address this problem. From understanding the special characteristics of various microbes to financing challenges, the volume provides an essential primer on a neglected but highly relevant topic. Physicians, scientists, policymakers, public health practitioners and anyone with an interest in the field of pandemics, emerging infectious disease, biosecurity, and global health security will find it a valuable and insightful resource.
Epidemics. --- Disease outbreaks --- Diseases --- Outbreaks of disease --- Pestilences --- Communicable diseases --- Outbreaks --- Epidemics --- Global health. --- Risk Assessment --- prevention & control. --- methods. --- International Health --- Worldwide Health --- International Health Problems --- World Health --- Health Problem, International --- Health Problems, International --- Health, Global --- Health, International --- Health, World --- Health, Worldwide --- Healths, International --- International Health Problem --- International Healths --- Problem, International Health --- Problems, International Health --- World Health Organization --- Pandemics --- Immunology. --- Health promotion. --- Epidemiology. --- Infectious diseases. --- Human physiology. --- Vaccines. --- Health Promotion and Disease Prevention. --- Infectious Diseases. --- Human Physiology. --- Vaccine. --- Biologicals --- Human biology --- Medical sciences --- Physiology --- Human body --- Public health --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education --- Immunobiology --- Life sciences --- Serology --- Malalties infeccioses --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Salut pública --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi
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This book aims to concisely present the most common types of musculoskeletal infections and demonstrate the key components of accurate diagnosis, treatment, and management. Written by experts in both infectious diseases and orthopaedics, the text takes a reader-friendly approach that is ideal for medical professionals in training as students or as seasoned practitioners strengthening their skills. Case chapters include a color clinical image as well as radiographic images for superior visual support. They conclude with 4-6 bulleted high yield points for quick reference and reader retention. The cases presented in Musculoskeletal Infections: A Clinical Case Book provide relevant and challenging diagnostic and management issues in musculoskeletal infectious disease, with an emphasis on clinical pearls and medical-surgical collaboration.
Musculoskeletal system --- Infections. --- Locomotor system --- Musculo-skeletal system --- Skeletomuscular system --- Infectious diseases. --- Orthopedics. --- Primary care (Medicine). --- Emergency medicine. --- Health promotion. --- Epidemiology. --- Infectious Diseases. --- Primary Care Medicine. --- Emergency Medicine. --- Health Promotion and Disease Prevention. --- Diseases --- Public health --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education --- Medicine, Emergency --- Medicine --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Primary medical care --- Medical care --- Orthopaedics --- Orthopedia --- Surgery --- Infeccions --- Malalties de l'aparell locomotor --- Ortopèdia --- Cirurgia --- Aparells ortopèdics --- Cirurgia ortopèdica --- Infermeria ortopèdica --- Manipulació (Terapèutica) --- Ortopèdia geriàtrica --- Ortopèdia veterinària --- Malalties dels ossos --- Malalties del sistema músculo-esquelètic --- Malalties músculo-esquelètiques --- Malalties --- Malalties de les articulacions --- Malalties del peu --- Malalties musculars --- Reumatisme --- Infecció --- Etiologia --- Microbiologia mèdica --- Abscessos --- Artritis infecciosa --- Infeccions del tracte urinari --- Malalties transmeses per l'aigua --- Infeccions en els infants --- Infeccions nosocomials --- Infeccions oportunistes --- Infeccions respiratòries
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This book systematically assesses the risk of 21 major infectious diseases threatening BRI countries. It consists of 14 chapters. Chapter 1 is an overview. Chapter 2 introduces the history of health cooperation between China and other BRI countries. Chapters 3-14 introduce the prevalence of major infectious diseases threatening BRI countries such as cholera, vaccine preventable diseases (polio, measles, meningitis, Japanese encephalitis, diphtheria, hepatitis A), tuberculosis, influenza, and insect-borne diseases (Dengue fever, Zika virus disease, yellow fever, Chikungunya, Rift Valley fever), plague, malaria, Ebola virus disease, MERS, schistosomiasis, COVID-19 and AIDS, and risk factors, principles and cases of their prevention and control. It is a useful reference book in the research of infectious disease control and prevention, and provides historical experience and lessons learned. It also provides decision support for international cooperation among BRI countries in the field of epidemic prevention and control in the future.
Public health. --- Epidemiology. --- Public Health. --- Diseases --- Public health --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Communicable diseases --- Prevention. --- Malalties infeccioses --- Medicina preventiva --- Àsia --- Euràsia --- Prevenció de les malalties --- Profilaxi --- Programes de prevenció --- Higiene --- Veterinària preventiva --- Avaluació del risc per la salut --- Cribratge --- Medicina social --- Salut pública --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi --- Terra (Planeta) --- Europa --- Estats i territoris --- Àsia central --- Eufrates (Àsia : Curs d'aigua) --- Eufrates (Àsia : Vall) --- Himàlaia (Àsia : Serralada) --- Jònia (Turquia i Grècia) --- Orient --- Tigris (Àsia : Curs d'aigua)
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Parasitology. --- Communicable diseases --- Etiology. --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics --- Biology --- Malalties infeccioses --- Etiologia --- Biologia molecular --- Nanomedicina --- Medicina --- Nanotecnologia --- Biofísica molecular --- Bioquímica molecular --- Biofísica --- Bioquímica --- Histoquímica --- Biologia molecular vegetal --- Codi genètic --- Diagnòstic molecular --- Endocrinologia molecular --- Evolució molecular --- Farmacologia molecular --- Genètica molecular --- Glicòmica --- Metabolòmica --- Microbiologia molecular --- Neurobiologia molecular --- Patologia molecular --- Proteòmica --- Reconeixement molecular --- Biomolècules --- Causes de les malalties --- Diagnòstics etiològics --- Etiologia mèdica --- Patogènesi --- Patologia --- Accidents --- Infeccions --- Traumatisme --- Factors de risc en les malalties --- Contagi --- Malalties contagioses --- Malalties encomanadisses --- Malalties transmissibles --- Microbiologia mèdica --- Salut pública --- Abscessos --- Desinfecció --- Malalties bacterianes --- Malalties emergents --- Malalties infeccioses en els infants --- Malalties d'origen alimentari --- Malalties parasitàries --- Malalties per prions --- Malalties víriques --- Micosi --- Zoonosi
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