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Abnormal behavior. --- Stereotypies. --- Stereotypy.

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Omics technologies such as proteomics, genomics, and metabolomics are widely applied for the identification and characterization of new molecular signatures. However, molecular profiling that makes it possible to understand neurodegenerative diseases has been relatively insufficient. Brain diseases such as neurodegenerative diseases and emotional disorders need integrative understanding which draws on a more reliable hypothesis for pathology, which can be accomplished via in-depth study of molecular information. Recently, multi-omics technologies have been eagerly applied to a diverse range of diseases. As this includes multiple molecular profiling, metadata, and Big Data processing with informatics and computer science, it is possible to provide new macroscopic and microscopic insights in order to better understand diseases. This Special Issue will introduce recent technological advances in multi-omics and the application of omics technology to brain diseases.

Research & information: general --- schizophrenia --- abnormal behavior gene set --- region --- differentially expressed genes --- de novo mutation --- copy number variant --- SIDS --- newborn infant --- genetic polymorphism --- neurotransmitter --- epigenetics --- epigenome --- zinc finger domain --- zinc finger motif --- zinc finger proteins --- zinc metalloproteins --- flow infusion analysis --- chloride adducts --- ceramides --- sphingolipids --- glycerophosphocholines --- human brain --- NAD+ --- nicotinamide --- ageing --- plasma --- biomarker --- CNV --- PPI --- spatiotemporal network --- chromosome 22q11.21 --- DGCR8 --- Orthosiphon stamineus --- plant-derived proteins --- neuroprotective --- SH-SY5Y cell model --- hydrogen peroxide --- CSF --- miRNAs --- neurological diseases --- OpenArray --- morphine --- withdrawal --- brain --- proteomics --- synaptic plasticity --- Alzheimer’s disease --- microfluidics --- lab-on-chip --- 3D culture --- organ-on-chip --- n/a --- Alzheimer's disease

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Clinical psychology based on gender medicine is a core topic of this Special Issue. In general, consideration of women’s mental health is limited; however, it is important to consider subjective wellbeing factors connected with cultural, environmental, epigenetic and personality aspects. Many factors, such as the roles assigned to women nowadays in social and work contexts, can act as predisposing conditions in the etiology of the psychopathological frame, particularly affective disorders. Furthermore, in the developmental life of a woman, important risk factors can be highlighted, such as the vulnerability to psychological distress in women and couples. In particular, the topic addresses the individual maternal requirements for successful transition to healthy motherhood and innovative programs based on gender medicine in the life cycle considering student and elderly experiences. The connection of psychological vulnerability to the environment and repercussions for relationships have been studied in connection with the COVID-19 lockdown, induced changes in women’s psychological distress and research regarding sexual arousal, self-image and mental wellbeing. Psychological and emotional forms of violence in couples, such as IPV, is another point highlighting new trend of assessments (i.e., Intimate Partner Violence EAPA-P) and ad hoc treatment in emotional regulation and resilience. Psychological support for women is central to the prevention of psychopathology, especially in relation to subthreshold traits; finally, the topic offers an overview of ad hoc treatments in clinical contexts.

stress --- medical student --- temperament --- self-esteem --- optimism --- stress response --- gender differences --- social behavior --- attachment --- touch avoidance --- network analysis --- intimate partner violence --- psychological treatment --- randomized controlled trial --- posttraumatic stress --- effectiveness --- eating abnormal behavior --- pro-ana and pro-mia websites --- female adolescents --- distress --- self-efficacy --- maternal confidence --- maternal wellbeing --- post-partum --- fall --- women --- health-related quality of life --- South Korea --- COVID-19 --- principal component analysis --- emotion regulation --- social stability status --- intolerance of uncertainly --- Italian population --- psychological violence --- self-report --- violence against women --- gender-based violence --- domestic violence --- assessment --- mindfulness --- newborn --- mother-infant --- maternal behavior --- mother-infant interaction --- maternal parenting stress --- maternal support --- sexuality --- body image

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Clinical psychology based on gender medicine is a core topic of this Special Issue. In general, consideration of women’s mental health is limited; however, it is important to consider subjective wellbeing factors connected with cultural, environmental, epigenetic and personality aspects. Many factors, such as the roles assigned to women nowadays in social and work contexts, can act as predisposing conditions in the etiology of the psychopathological frame, particularly affective disorders. Furthermore, in the developmental life of a woman, important risk factors can be highlighted, such as the vulnerability to psychological distress in women and couples. In particular, the topic addresses the individual maternal requirements for successful transition to healthy motherhood and innovative programs based on gender medicine in the life cycle considering student and elderly experiences. The connection of psychological vulnerability to the environment and repercussions for relationships have been studied in connection with the COVID-19 lockdown, induced changes in women’s psychological distress and research regarding sexual arousal, self-image and mental wellbeing. Psychological and emotional forms of violence in couples, such as IPV, is another point highlighting new trend of assessments (i.e., Intimate Partner Violence EAPA-P) and ad hoc treatment in emotional regulation and resilience. Psychological support for women is central to the prevention of psychopathology, especially in relation to subthreshold traits; finally, the topic offers an overview of ad hoc treatments in clinical contexts.

Psychology --- stress --- medical student --- temperament --- self-esteem --- optimism --- stress response --- gender differences --- social behavior --- attachment --- touch avoidance --- network analysis --- intimate partner violence --- psychological treatment --- randomized controlled trial --- posttraumatic stress --- effectiveness --- eating abnormal behavior --- pro-ana and pro-mia websites --- female adolescents --- distress --- self-efficacy --- maternal confidence --- maternal wellbeing --- post-partum --- fall --- women --- health-related quality of life --- South Korea --- COVID-19 --- principal component analysis --- emotion regulation --- social stability status --- intolerance of uncertainly --- Italian population --- psychological violence --- self-report --- violence against women --- gender-based violence --- domestic violence --- assessment --- mindfulness --- newborn --- mother-infant --- maternal behavior --- mother-infant interaction --- maternal parenting stress --- maternal support --- sexuality --- body image --- stress --- medical student --- temperament --- self-esteem --- optimism --- stress response --- gender differences --- social behavior --- attachment --- touch avoidance --- network analysis --- intimate partner violence --- psychological treatment --- randomized controlled trial --- posttraumatic stress --- effectiveness --- eating abnormal behavior --- pro-ana and pro-mia websites --- female adolescents --- distress --- self-efficacy --- maternal confidence --- maternal wellbeing --- post-partum --- fall --- women --- health-related quality of life --- South Korea --- COVID-19 --- principal component analysis --- emotion regulation --- social stability status --- intolerance of uncertainly --- Italian population --- psychological violence --- self-report --- violence against women --- gender-based violence --- domestic violence --- assessment --- mindfulness --- newborn --- mother-infant --- maternal behavior --- mother-infant interaction --- maternal parenting stress --- maternal support --- sexuality --- body image