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Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treatment.

Macrolide antibiotics. --- Antibiotics, Macrolide. --- Antibiotics. --- Streptomyces. --- Macrolides --- Antibiotiques --- Antibiotics --- Lactones --- Macrocyclic compounds

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HYPOGLYCAEMIC AGENTS --- LEUKOCYTE ELASTASE (INHIBITORS OF HUMAN...) --- AZIDO GROUP --- GASTRIC H+/K+ -ATPase INHIBITORS --- ANTIBIOTICS, MACROLIDE --- BETA-LACTAMASE --- TARGET FOR DRUG DESIGN --- DRUG DESIGN --- SILVER --- ENDOTHELINS --- POTASSIUM CHANNEL ACTIVATORS --- STRUCTURE-ACTIVITY RELATIONSHIPS --- INHIBITION OF THE PHARMACOLOGICAL EFFECTS