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Aldosterone

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ALDOSTERONE

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Aldosterone --- Biosynthesis.

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Aldosterone --- Hyperaldosteronism

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This dissertation by Ravi Kumar Dutta focuses on the genetic and molecular alterations in aldosterone-producing adenomas (APAs), a type of adrenal tumor that causes excessive production of aldosterone, leading to hypertension. The research explores mutations in several genes, including KCNJ5, ATP1A1, and CALHM2, which are involved in APAs. The study identifies both hereditary and sporadic mutations, contributing to a better understanding of the mechanisms behind these tumors. The findings may lead to more targeted treatments for APAs, offering alternatives to surgical intervention. The intended audience includes medical researchers and professionals in the field of endocrinology.

Aldosterone. --- Adrenal glands. --- Aldosterone --- Adrenal glands