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582.282.232 --- 663.12 --- 575.113 --- 577.212 --- 57.083.1 --- Sacharomycetaceae --- Yeasts in general. Brewing yeast. Ascending and descending yeasts --- Gene. Genetic apparatus. Genome --- Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- Microbiological methods and techniques --- 57.083.1 Microbiological methods and techniques --- 577.212 Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- 575.113 Gene. Genetic apparatus. Genome --- 663.12 Yeasts in general. Brewing yeast. Ascending and descending yeasts --- 582.282.232 Sacharomycetaceae --- genomes --- nomenclature --- Yeasts --- chromosomes --- gene expression --- proteins --- Immunology --- Mutation --- mutation --- Nomenclature --- Yeast fungi --- Genetics --- mutation. --- nomenclature.
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As more and more plant genomes are sequenced, plant researchers have been inundated with an avalanche of novel methodologies to identify the function of tens of thousands of plant genes. In Plant Functional Genomics, Erich Grotewold has assembled a team of leading plant scientists to describe in detail the most commonly used methods for investigating plant gene function in a wide variety of plants, during plant pathogen interactions, and even in algae. These readily reproducible protocols include computational, molecular, and genetic methodologies designed for both general and specific problems. Here the reader will learn how to identify genes in complex systems that have large genomes, few cells, and mixed cell systems. Readers will also learn the use of powerful computational and statistical tools to help predict gene function, either on the basis of comparative genomics, or from the analysis of complex genome sequences. Because establishing gene function relies on the identification of phenotypes, the authors expand the concept of phenotypes, including the use of multiple outputs as the ultimate phenotypic result of changes in gene activity. Numerous loss-of-function and gain-of-function techniques for discovering gene function are presented in step-by-step detail. Comprehensive and highly practical, Plant Functional Genomics offers plant biologists readily reproducible computational, molecular, and genetic protocols, powerful tools that will enable them, with little or no experience, successfully to investigate any gene function with the most recent methodologies.
577.212 --- 575.113 --- 57.088 --- 631.528.2 --- Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- Gene. Genetic apparatus. Genome --- Special methods and techniques for studing biological molecules. Separation. Centrifuging. X-ray study. Radioisotope methods --- Genome mutations, polyploidy, haploidy --- Electronic books. -- local. --- Genomics. --- Plant gene expression. --- Plant molecular genetics. --- Plant molecular genetics --- Plant gene expression --- Genomics --- Botany --- Earth & Environmental Sciences --- Plant Ecology --- Economic sanctions. --- Security, International. --- 631.528.2 Genome mutations, polyploidy, haploidy --- 57.088 Special methods and techniques for studing biological molecules. Separation. Centrifuging. X-ray study. Radioisotope methods --- 575.113 Gene. Genetic apparatus. Genome --- 577.212 Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- Sanctions. --- Molecular genetics --- Plant genetics --- Plant molecular biology --- Gene expression --- Genome research --- Genomes --- Research --- Sanctions économiques --- Sécurité internationale --- United Nations --- Botany. --- Plant Sciences. --- Botanical science --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Biology --- Natural history --- Plants --- Floristic botany
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Genomics --- Gene mapping. --- 57.087.1 --- 577.212 --- 575.113 --- 575.113 Gene. Genetic apparatus. Genome --- Gene. Genetic apparatus. Genome --- 577.212 Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- 57.087.1 Biometry. Statistical study and treatment of biological data --- Biometry. Statistical study and treatment of biological data --- Chromosome mapping --- Genetic mapping --- Genome mapping --- Linkage mapping (Genetics) --- Mapping, Gene --- Genetics --- Genome research --- Genomes --- Molecular genetics --- Statistical methods. --- Technique --- Research --- Génétique --- Gene mapping --- Statistical methods --- Mathematical statistics --- Cartes chromosomiques --- Méthodes statistiques --- Genomics - Statistical methods --- GENETIC TECHNIQUES --- CHROMOSOME MAPPING --- QTL MAPPING --- QUANTITATIVE TRAITS --- STATISTICS & NUMERICAL DATA
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Human genetics --- Base Sequence --- Chromosome Mapping --- Genetics --- Gene mapping --- Genomics --- Nucleotide sequence --- Cartes chromosomiques --- Génomique --- Séquence nucléotidique --- periodicals --- Periodicals --- Périodiques --- Cytogenetics --- Base Sequence. --- Chromosome Mapping. --- Genetics. --- Génomes --- 577.212 --- 575.113.1 --- 575 <05> --- Genetic Processes --- Genetic Structures --- Genetic Phenomena --- Genome Mapping --- Gene Mapping --- Linkage Mapping --- Chromosome Mappings --- Gene Mappings --- Genome Mappings --- Linkage Mappings --- Mapping, Chromosome --- Mapping, Gene --- Mapping, Genome --- Mapping, Linkage --- Mappings, Chromosome --- Mappings, Gene --- Mappings, Genome --- Mappings, Linkage --- Genetic Markers --- Cytogenetic Analysis --- Gene Order --- Synteny --- DNA Sequences --- DNA Sequence --- Nucleotide Sequence --- RNA Sequence --- Base Sequences --- Nucleotide Sequences --- RNA Sequences --- Sequence, Base --- Sequence, DNA --- Sequence, Nucleotide --- Sequence, RNA --- Sequences, Base --- Sequences, DNA --- Sequences, Nucleotide --- Sequences, RNA --- Genes --- Nucleotides --- Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- Inheritance information. Nature of gene. Genetic code --- General genetics. General cytogenetics. Immunogenetics. Evolution. Speciation. Phylogeny--Tijdschriften --- Life Sciences --- Bioinformatics --- General and Others --- Biology --- Cytogenetics. --- Life Sciences. --- Genomics. --- 575 <05> General genetics. General cytogenetics. Immunogenetics. Evolution. Speciation. Phylogeny--Tijdschriften --- 575.113.1 Inheritance information. Nature of gene. Genetic code --- 577.212 Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- Gene mapping. --- Nucleotide sequence. --- Génomique --- Séquence nucléotidique --- Périodiques --- EJBIOMO ELSEVIER-E EPUB-ALPHA-G EPUB-PER-FT --- periodicals. --- genomics --- genome sequencing --- functional genomics --- evolutionary and comparative genomics --- computational biology --- bioinformatics --- Chromosome mapping --- Genetic mapping --- Genome mapping --- Linkage mapping (Genetics) --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Nucleic acids --- Sequence alignment (Bioinformatics) --- Technique --- Analysis
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This book is targeted to biologists with limited statistical background and to statisticians and computer scientists interested in being effective collaborators on multi-disciplinary DNA microarray projects. State-of-the-art analysis methods are presented with minimal mathematical notation and a focus on concepts. This book is unique because it is authored by statisticians at the National Cancer Institute who are actively involved in the application of microarray technology. Many laboratories are not equipped to effectively design and analyze studies that take advantage of the promise of microarrays. Many of the software packages available to biologists were developed without involvement of statisticians experienced in such studies and contain tools that may not be optimal for particular applications. This book provides a sound preparation for designing microarray studies that have clear objectives, and for selecting analysis tools and strategies that provide clear and valid answers. The book offers an in depth understanding of the design and analysis of experiments utilizing microarrays and should benefit scientists regardless of what software packages they prefer. In order to provide all readers with hands on experience in data analysis, it includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is freely available from the National Cancer Institute for non-commercial use. The authors are current or former members of the Biometric Research Branch at the National Cancer Institute. They have collaborated on major biomedical studies utilizing microarrays and in the development of statistical methodology for the design and analysis of microarray investigations. Dr. Simon, chief of the branch, is also the architect of BRB-ArrayTools.
Mathematical statistics --- DNA microarrays --- Puces à ADN --- Statistical methods --- Méthodes statistiques --- DNA microarrays -- Statistical methods. --- Electronic books. -- local. --- Genetics -- Research. --- Statistics as Topic --- Decision Support Techniques --- Molecular Probe Techniques --- Methods --- Sequence Analysis --- Microarray Analysis --- Nucleic Acid Hybridization --- Research --- Genetic Techniques --- Medical Informatics Applications --- Investigative Techniques --- Microchip Analytical Procedures --- Epidemiologic Methods --- Science --- Health Care Evaluation Mechanisms --- Chemistry Techniques, Analytical --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Natural Science Disciplines --- Quality of Health Care --- Medical Informatics --- Public Health --- Environment and Public Health --- Information Science --- Health Care Quality, Access, and Evaluation --- Disciplines and Occupations --- Health Care --- Data Interpretation, Statistical --- Research Design --- Oligonucleotide Array Sequence Analysis --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- 519.242 --- 577.212 --- Experimental design. Optimal designs. Block designs --- Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- 577.212 Central dogma of molecular biology. Coding of inheritance information. The genetic code and its chemical nature --- 519.242 Experimental design. Optimal designs. Block designs --- Genetics --- Statistical methods. --- Research. --- Puces à ADN --- Méthodes statistiques --- EPUB-LIV-FT SPRINGER-B --- Medicine. --- Cancer research. --- Molecular biology. --- Pharmacology. --- Health informatics. --- Bioinformatics. --- Statistics. --- Biomedicine. --- Cancer Research. --- Statistics for Life Sciences, Medicine, Health Sciences. --- Molecular Medicine. --- Pharmacology/Toxicology. --- Health Informatics. --- DNA biochips --- Microarrays, DNA --- Biochips --- Immobilized nucleic acids --- Oncology. --- Toxicology. --- Medical records --- Data processing. --- Statistics . --- Clinical informatics --- Health informatics --- Medical information science --- Information science --- Medicine --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Statistical analysis --- Statistical data --- Statistical science --- Mathematics --- Econometrics --- Bio-informatics --- Biological informatics --- Biology --- Computational biology --- Cancer research --- Data processing --- Physiological effect
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