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Dissertation
The last mile of the protein folding problem
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ISBN: 9090185089 Year: 2004

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Protein-solvent interactions
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ISBN: 0824792394 9780824792398 Year: 1995 Publisher: New York, N.Y. M. Dekker

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Presenting integrated analyses of the most recent results, Protein-Solvent Interactions examines the construction of proteins and the protein devices that underlie protein function and stability, furnishing a new paradigm for protein research ... reviews x-ray crystallographic results on the patterns of solvent structure in and around proteins ... studies protein hydration, glass transitions, and the plasticizing action of water, leading to a unifying description of protein dynamics ... highlights results from dielectric relaxation, Rayleigh scattering of Mossbauer radiation, positron annihilation lifetime spectroscopy, hydrogen isotope exchange, and flash photolysis techniques ... outlines Brownian dynamics, Kramers's theory, and the effects of solvent viscosity on protein dynamics ... defines the thermodynamic nonideality of proteins in water-cosolvent mixtures in terms of excluded volume and preferential interactions, supplying a new appreciation of binding phenomena ... offers an inventory of solvent-induced effects on protein stability, association, and folding and shows how to obtain the missing thermodynamic data ... introduces a new approach to protein separation problems ... and much more. This practical resource covers the latest advances in the interactions of proteins with their solvent environment and provides fundamental physical information useful for the application of proteins in biotechnology and industrial processes. It discusses in detail structural, dynamic, and thermodynamic aspects of protein hydration as well as proteins in aqueous and organic solvents as they relate to protein function, stability, and folding.

Fundamentals of Protein Structure and Function
Authors: ---
ISBN: 9780387263526 9780387684802 0387263527 0387684808 Year: 2007 Publisher: Boston, MA Springer

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Fundamentals of Protein Structure and Function Engelbert Buxbaum, Dr. rer. nat. This book serves as an introduction to the fundamentals of protein structure and function. Starting with their make up from simple building blocks called amino acids, the 3-dimensional structure of proteins is explained. This is followed by an introduction into enzymology and modern concepts of enzyme kinetics, taking into account the physiological and medical significance of this often neglected topic. Also covered in the text are enzymes, biocatalysts, enzyme kinetics, hemoglobin, myoglobin, prion proteins, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins into mitochondria, transport of proteins between cell compartments, transport of solutes across membranes, analytic techniques, protein-ligand interactions, protein purification, and protein structure, size and shape, emphasizing the link between protein structure, physiological function and medical significance. This book is an introductory text for researchers in protein biochemistry, molecular biology, cell biology, chemistry, biophysics and biomedical research. The book also makes an ideal textbook for graduate and advanced undergraduate courses in protein structure and function, and a supplementary text for related courses. About the Author Dr. Buxbaum is a biochemist with interest in enzymology and protein science. Dr. Buxbaum has been working on the biochemistry of membrane transport proteins for almost 20 years and has taught courses in biochemistry and molecular medicine at several universities. "The analytical descriptions of structure, biophysics and function of proteins is an extremely important aspect of today's education in biochemistry." Martin Sagermann, Ph.D. University of California, Santa Barbara

Protein metabolism
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ISBN: 0444803467 0444801715 0444801510 9780444801715 9780444803467 Year: 1982 Volume: 19B/1-2 Publisher: Amsterdam Elsevier

Precursor processing in the biosynthesis of proteins
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ISBN: 0897660730 0897660722 9780897660730 Year: 1980 Volume: 343 Publisher: New York (N.Y.) New York academy of sciences

Proteins : structure and function
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ISBN: 9780471498940 9780471498933 0471498947 0471498939 Year: 2007 Publisher: Chichester J. Wiley & Sons

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"Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of proteins."--Jacket.


Book
Protein deposition in animals
Authors: ---
ISBN: 040810676X 1322209502 1483161811 Year: 1980 Publisher: London Butterworths


Periodical
Protein science.
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ISSN: 09618368 Year: 1992 Publisher: Hoboken Wiley-Blackwell.

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Protein Science encompasses the structure, function, and biochemical significance of proteins; their role in molecular and cell biology, genetics, and evolution; and their regulation and mechanisms of action. Representative topics include, but are not limited to, the structure of proteins and strategies of determining protein structure by chemical, biophysical, and recombinant methods; peptides; protein domains; protein folding and molecular dynamics; novel isolation procedures; enzyme action and regulation; interactions of proteins with nucleic acids, lipids, ligands, and other proteins; receptor-mediated signal transduction and other trans-membrane phenomena; the functions of proteins in replication, supramolecular assembly, immune reactions, development, and other biological processes; protein trafficking, synthesis, and sorting; and the recognition, localization and signaling of proteins. In addition to the investigative techniques already mentioned, the Journal will publish results of protein-centered work involving sequencing, modification, and mass spectrometry; cDNA, mutagenesis, and cloning; computational analysis; isolation and characterization; thermodynamics and hydrodynamics; kinetics; and equilibrium phenomena.

Computational methods for protein structure prediction and modeling. 2: Structure prediction.
Authors: --- ---
ISBN: 0387333215 9780387333212 1441922067 9786612823961 1282823965 0387688250 Year: 2007 Publisher: New York (N.Y.) Springer

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Volume 2 of this two-volume sequence focuses on protein structure prediction and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.

Mechanisms of protein folding
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ISBN: 0199637881 019963789X 9780199637881 9780199637898 Year: 2000 Volume: 32 Publisher: Oxford Oxford university press

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