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In this book, we collected scientific articles, including reviews and research articles, showcasing the lastest literature on the importance of biochemical biomarkers in the management of neurodegenerative diseases, from screening to diagnosis, prognosis, and treatment.

Medicine --- Neurosciences --- GLUT3 --- cerebral ischemia --- MCAO --- resveratrol --- astrocytes --- AMPK --- amyotrophic lateral sclerosis --- GSK3β --- neurodegenerative disease --- PD --- Arylsulfatase A --- lysosomes --- GWAS --- Gaucher's disease --- prognostic biomarker --- focused ultrasound --- MR-guided focused ultrasound --- high-intensity focused ultrasound ablation --- magnetic resonance imaging --- image quality --- stereotaxic techniques --- essential tremor --- Alzheimer's disease --- amyloid precursor protein --- Tyr682 residue --- YENPTY motif --- Fyn tyrosine kinase --- amyloid beta --- ALS --- biomarker --- beta amyloid --- AD --- biomarkers --- SARS-CoV-2 --- neuroinflammation --- neurodegenerative nisease --- nervous system --- Alzheimer's Disease --- Vitamin D --- 25(OH)D levels --- Vitamin D deficiency --- inherited neuromuscular disorders --- rare diseases --- multiple sclerosis --- genetic --- polymorphisms --- FOXP3 --- GATA3 --- vitamin D --- neuromelanin --- nigrosome-1 --- iron --- radiomics --- neurodegenerative diseases --- Parkinson's disease --- parkinsonian disorders --- GLUT3 --- cerebral ischemia --- MCAO --- resveratrol --- astrocytes --- AMPK --- amyotrophic lateral sclerosis --- GSK3β --- neurodegenerative disease --- PD --- Arylsulfatase A --- lysosomes --- GWAS --- Gaucher's disease --- prognostic biomarker --- focused ultrasound --- MR-guided focused ultrasound --- high-intensity focused ultrasound ablation --- magnetic resonance imaging --- image quality --- stereotaxic techniques --- essential tremor --- Alzheimer's disease --- amyloid precursor protein --- Tyr682 residue --- YENPTY motif --- Fyn tyrosine kinase --- amyloid beta --- ALS --- biomarker --- beta amyloid --- AD --- biomarkers --- SARS-CoV-2 --- neuroinflammation --- neurodegenerative nisease --- nervous system --- Alzheimer's Disease --- Vitamin D --- 25(OH)D levels --- Vitamin D deficiency --- inherited neuromuscular disorders --- rare diseases --- multiple sclerosis --- genetic --- polymorphisms --- FOXP3 --- GATA3 --- vitamin D --- neuromelanin --- nigrosome-1 --- iron --- radiomics --- neurodegenerative diseases --- Parkinson's disease --- parkinsonian disorders

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Many things have been said and written on the skeletal and non-skeletal effects of vitamin D, but the largest recent interventional studies are generally negative. How should we thus position ourselves in 2020? Should we say “stop” or “not yet”? Indeed, the aging of the population, as well as new challenges and discoveries, is still triggering interest in this old molecule. In this Special Edition of Nutrients, we invited top experts to give their opinion on this important debate. We also encouraged scientists to submit their latest research on nutritional requirements in the general population and in high-risk groups, as well as treatment strategies, epidemiology, analytical updates and new devices for vitamin D measurement and the effect of vitamin D on bone and extra-skeletal health. As readers will see, this Special Issue reinforces the high prevalence of vitamin deficiency and insufficiency in the general population and supports the safety of this low-cost molecule, revealing new perspectives regarding the extra-skeletal effects of vitamin D.

Humanities --- Social interaction --- vitamin D --- obesity --- weight-loss --- body composition --- 25(OH)vitamin D --- biomarkers --- dietary survey --- public health --- EU Menu --- Slovenia --- Europe --- ageing --- older persons --- sensible sun exposure --- cutaneous synthesis --- vitamin D3 --- natural sunlight --- serum 25(OH)D --- autoimmune hepatitis --- primary biliary cholangitis --- health-related quality of life --- mental well-being --- breastmilk --- infant --- mother --- plasma --- vitamin D metabolites --- 3-Epi25(OH)D3 --- 25-hvdroxyvitamin --- vitamin D treatment --- idiopathic hypercalciuria --- urolithiasis --- children --- bone density --- head and neck cancer --- racial disparities --- chemoprevention --- UVB --- microRNA --- proteomic profiling --- vitamin D status --- disability --- very old adults --- vulvovaginal atrophy --- VVA --- vaginal maturation index --- VMI --- vaginal health --- ergocalciferol --- vitamin D supplement --- sunlight exposure --- barriers --- indoor workers --- female --- focus group discussion --- vitamin D --- obesity --- weight-loss --- body composition --- 25(OH)vitamin D --- biomarkers --- dietary survey --- public health --- EU Menu --- Slovenia --- Europe --- ageing --- older persons --- sensible sun exposure --- cutaneous synthesis --- vitamin D3 --- natural sunlight --- serum 25(OH)D --- autoimmune hepatitis --- primary biliary cholangitis --- health-related quality of life --- mental well-being --- breastmilk --- infant --- mother --- plasma --- vitamin D metabolites --- 3-Epi25(OH)D3 --- 25-hvdroxyvitamin --- vitamin D treatment --- idiopathic hypercalciuria --- urolithiasis --- children --- bone density --- head and neck cancer --- racial disparities --- chemoprevention --- UVB --- microRNA --- proteomic profiling --- vitamin D status --- disability --- very old adults --- vulvovaginal atrophy --- VVA --- vaginal maturation index --- VMI --- vaginal health --- ergocalciferol --- vitamin D supplement --- sunlight exposure --- barriers --- indoor workers --- female --- focus group discussion

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Calcium is the main mineral in the body, involved in a variety of structural and functional roles. The maintenance of calcium homeostasis is perhaps the most studied function of vitamin D. This Special Issue of Nutrients, “Calcium, Vitamin D and Health” contains 12 original publications and two reviews investigating the contribution of (mainly) vitamin D and calcium on relevant health outcomes in a variety of populations, which reflect the evolving and broad interest of researchers on this topic.

Humanities --- Social interaction --- Vitamin D --- females --- exercise --- sedentary lifestyle --- nutrition --- elderly --- vitamin D --- depression --- depressive symptoms --- Mendelian randomization --- cyclists --- adolescence --- bone turnover --- osteocalcin --- dietary calcium intake --- adolescent boys --- adiposity --- percentage of body fat --- insulin resistance --- adipocytokines --- type 1 diabetes --- type 2 diabetes --- metabolic syndrome --- autoimmune --- children --- cancer --- vitamin D metabolites --- vitamin D supplementation --- vitamin D metabolite ratio --- randomized controlled trial --- 24,25-dihydroxy vitamin D --- calcitriol --- body mass index --- lean mass --- fat mass --- bone mineral density --- postmenopausal women --- obesity --- macronutrients --- sunlight --- physical activity --- season --- body composition --- strength --- bone health --- mediation --- childhood --- enriched food --- child --- cholecalciferol --- ergocalciferols --- dairy products --- multiple sclerosis --- fibroblast growth factor 23 --- vitamin D binding protein --- hypovitaminosis D --- 25-hydroxyvitamin D --- postherpetic neuralgia --- spontaneous pain --- brush-evoked pain --- varicella-zoster virus immunoglobulin --- DN4questionnaire --- vitamin D deficiency --- vitamin D supplements --- weight loss --- low-density lipoprotein (LDL) cholesterol --- high-density lipoprotein (HDL) cholesterol --- triglycerides (TG) --- blood pressure --- n/a --- athletic performance --- 25(OH)D --- supplementation --- deficiency --- athlete

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In this book, we collected scientific articles, including reviews and research articles, showcasing the lastest literature on the importance of biochemical biomarkers in the management of neurodegenerative diseases, from screening to diagnosis, prognosis, and treatment.

Medicine --- Neurosciences --- GLUT3 --- cerebral ischemia --- MCAO --- resveratrol --- astrocytes --- AMPK --- amyotrophic lateral sclerosis --- GSK3β --- neurodegenerative disease --- PD --- Arylsulfatase A --- lysosomes --- GWAS --- Gaucher’s disease --- prognostic biomarker --- focused ultrasound --- MR-guided focused ultrasound --- high-intensity focused ultrasound ablation --- magnetic resonance imaging --- image quality --- stereotaxic techniques --- essential tremor --- Alzheimer’s disease --- amyloid precursor protein --- Tyr682 residue --- YENPTY motif --- Fyn tyrosine kinase --- amyloid beta --- ALS --- biomarker --- beta amyloid --- AD --- biomarkers --- SARS-CoV-2 --- neuroinflammation --- neurodegenerative nisease --- nervous system --- Alzheimer’s Disease --- Vitamin D --- 25(OH)D levels --- Vitamin D deficiency --- inherited neuromuscular disorders --- rare diseases --- multiple sclerosis --- genetic --- polymorphisms --- FOXP3 --- GATA3 --- vitamin D --- neuromelanin --- nigrosome-1 --- iron --- radiomics --- neurodegenerative diseases --- Parkinson’s disease --- parkinsonian disorders --- n/a --- Gaucher's disease --- Alzheimer's disease --- Alzheimer's Disease --- Parkinson's disease

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Many things have been said and written on the skeletal and non-skeletal effects of vitamin D, but the largest recent interventional studies are generally negative. How should we thus position ourselves in 2020? Should we say “stop” or “not yet”? Indeed, the aging of the population, as well as new challenges and discoveries, is still triggering interest in this old molecule. In this Special Edition of Nutrients, we invited top experts to give their opinion on this important debate. We also encouraged scientists to submit their latest research on nutritional requirements in the general population and in high-risk groups, as well as treatment strategies, epidemiology, analytical updates and new devices for vitamin D measurement and the effect of vitamin D on bone and extra-skeletal health. As readers will see, this Special Issue reinforces the high prevalence of vitamin deficiency and insufficiency in the general population and supports the safety of this low-cost molecule, revealing new perspectives regarding the extra-skeletal effects of vitamin D.

vitamin D --- obesity --- weight–loss --- body composition --- 25(OH)vitamin D --- biomarkers --- dietary survey --- public health --- EU Menu --- Slovenia --- Europe --- ageing --- older persons --- sensible sun exposure --- cutaneous synthesis --- vitamin D3 --- natural sunlight --- serum 25(OH)D --- autoimmune hepatitis --- primary biliary cholangitis --- health-related quality of life --- mental well-being --- breastmilk --- infant --- mother --- plasma --- vitamin D metabolites --- 3-Epi25(OH)D3 --- 25-hvdroxyvitamin --- vitamin D treatment --- idiopathic hypercalciuria --- urolithiasis --- children --- bone density --- head and neck cancer --- racial disparities --- chemoprevention --- UVB --- microRNA --- proteomic profiling --- vitamin D status --- disability --- very old adults --- vulvovaginal atrophy --- VVA --- vaginal maturation index --- VMI --- vaginal health --- ergocalciferol --- vitamin D supplement --- sunlight exposure --- barriers --- indoor workers --- female --- focus group discussion --- n/a --- weight-loss