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In this brief, beautifully illustrated book, the authors introduce the reader to the basic science of medical microbiology and relate it to clinical practice. Integrating concise text, over 270 full-colour diagrams and selected photomicrographs, they provide an understanding of bacterial infection and give the reader the necessary grounding to select the right antibiotics and follow logical diagnostic and management strategies. Following introductory chapters on the nature, structure and function of bacteria, the principles are then applied to each body system in turn, dealing with organisms, pathogenesis, diagnosis, treatment and public health. There are also chapters on infection control emphasising the importance of good hygiene in preventing hospital acquired infection. In the context of new problem-based curricula, the book will be welcomed especially by medical students, trainee physicians and microbiologists, laboratory biomedical scientists and nurses working in infection control.

Bacteriologie. --- Medische microbiologie.

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General microbiology --- medische microbiologie --- medische laboratoriumtechnologie --- 579.61 --- Medische microbiologie

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laboratoriummethode --- medische microbiologie --- microbiologie --- voedingsmiddelenhygiëne --- voedingsmiddelentechnologie --- voedselmicrobiologie

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The present volume of Current Topics in Microbiology and Immunology c- tains seven chapters that illuminate various aspects of a protein's genesis and terminal fate in the endoplasmic reticulum (ER). This area is of immediate medical relevance and has blossomed, to no small extent, because of the study of molecules central to the function of the immune system [immunogl- ulins, T cell receptors, major histocompatibility complex (MHC)-encoded products]. Similarly, the clever strategies used by bacteria or viruses to gain a foothold in the host and ensure their continued survival have uncovered altogether new cell biological principles. It is therefore ?tting that a special volume be devoted to the interplay between pathways of protein degradation in the ER and a wide variety of pathogens. The concept of quality control emerged with the appreciation that, in the case of multimeric glycoproteins, any unpaired glycoprotein subunit had great dif?culties leaving its site of synthesis the ER and was destroyed instead. Free immunoglobulin heavy chains were probably the earliest documented example of this kind, and were long known to cause pathology when their accumulation went unchecked. Increased knowledge of the biosynthetic pathways of glycoproteins allowed the identi?cation of the ER as an important site where such quality control decisions were made. The T cell receptor for antigen, long considered the paradigm of this mode of degradation, led the way in these early explorations.

Medical microbiology, virology, parasitology --- medische microbiologie

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Advanced Techniques in Diagnostic Microbiology provides a comprehensive and up-to-date description of advanced methods that have evolved for the diagnosis of infectious diseases in the routine clinical microbiology laboratory. The book is divided into two sections. The first techniques section covers the principles and characteristics of techniques ranging from rapid antigen testing, to advanced antibody detection, to in vitro nucleic acid amplification techniques, and to nucleic acid microarray and mass spectrometry. Sufficient space is assigned to cover different nucleic acid amplification formats that are currently being used widely in the diagnostic microbiology field. Within each technique, examples are given regarding its application in the diagnostic field. Commercial product information, if available, is introduced with commentary in each chapter. If several test formats are available for a technique, objective comparisons are given to illustrate the contrasts of their advantages and disadvantages. The second applications section provides practical examples of application of these advanced techniques in several ââ‚Å“hotâ₠spots in the diagnostic field. A diverse team of authors presents authoritative and comprehensive information on sequence-based bacterial identification, blood and blood product screening, molecular diagnosis of sexually transmitted diseases, advances in mycobacterial diagnosis, novel and rapid emerging microorganism detection and genotyping, and future directions in the diagnostic microbiology field

Medical microbiology, virology, parasitology --- medische microbiologie