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Myeloproliferative Disorders --- Polycythemia --- Congresses

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Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: • Essential thrombocythemia (ET) – characterized by increased platelet count • Polycythemia vera (PV) – characterized by excessive production of red blood cells • Primary myelofibrosis – a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.

Myeloproliferative disorders. --- Myeloproliferative syndrome --- Bone marrow --- Diseases

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The diagnosis and monitoring of hematological malignancies is complex and requires a systematic approach. Morphology, cell phenotyping, cytogenetics and molecular genetics are essential, and the results must be integrated. Diagnostic Techniques in Hematological Malignancies details the principles and applications of each of these test types in the diagnosis of hematological malignancies in blood and bone marrow. The first section describes the test modalities - including methodological principles, data interpretation and limitations - and is illustrated by clinical examples. The second section focuses on the clinical entities, detailing the most appropriate tests for diagnosis, staging and monitoring of different hematological malignancies and includes test utilization to identify prognostic markers and potential therapeutic targets. With contributions from multiple international experts, this illustrated book is an essential resource for qualified and trainee hematologists, oncologists, and pathologists. It's a practical and useful guide, providing a rational and structured approach to the laboratory assessment of hematological malignancies.

Myeloproliferative disorders --- Leukemia --- Blood --- Diagnosis. --- Diseases --- Analysis.

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Bone Marrow --- Bone Marrow Diseases --- Bone marrow --- Myeloproliferative disorders --- Hematopoietic stem cells

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Introduction The understanding of the genetic, epigenetic, immuno- well as for practicing hematologists or oncologists. logical and biological causes of myeloproliferative dis- Each chapter follows a similar architecture and leads orders has substantially improved in the last few years. through epidemiology, genetic and molecular causes, Together with refined tools in pathology, the successful hematological and clinical findings, prognostic factors establishment of mouse models mimicking at least some and current treatment approaches of the diseases. of the myeloproliferative disorders, and murine models Effort has been made to point out the evolving field of novel drugs in this arena but simultaneously diff- allowing to carefully dissect the role of mutations and gene dosage effects of, for example JAK2, this has led to entiate between standard and experimental treatment ever increasing numbers of modified classification approaches. schemes. It is therefore important for the heamtologist Together with the co-editors and all the authors of or oncologist to keep up with this rapid change in classi- the various chapters I hope that the readers of the book fication language, the upcoming of new entities or differ- will enjoy reading and benefit from the information entiation between, or subclassification of, rare diseases provided.

Myeloid leukemia --Epidemiology. --- Myeloid leukemia --Pathophysiology. --- Myeloid leukemia --Treatment. --- Myeloproliferative disorders --Epidemiology. --- Myeloproliferative disorders --Pathophysiology. --- Myeloproliferative disorders --Treatment. --- Myeloproliferative disorders --- Myeloid leukemia --- Bone Marrow Diseases --- Leukemia --- Leukemia, Myeloid --- Myeloproliferative Disorders --- Neoplasms by Histologic Type --- Hematologic Diseases --- Neoplasms --- Hemic and Lymphatic Diseases --- Diseases --- Medicine --- Oncology --- Health & Biological Sciences --- Epidemiology --- Pathophysiology --- Treatment --- Bone marrow --- Myeloproliferative disorders. --- Myelodysplastic syndromes. --- Diseases. --- Dysmyelopoietic syndromes --- Myeloproliferative syndrome --- Dysplasia --- Medicine. --- Internal medicine. --- Blood transfusion. --- Oncology. --- Medicine & Public Health. --- Internal Medicine. --- Blood Transfusion Medicine. --- Syndromes --- Preleukemia --- Oncology  . --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Surgery --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Medicine, Internal --- Tumors --- Transfusion committees