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Pharmaceutical giants have doubled their investments in drug development in the past decade only to see new drug approvals remain constant. This book investigates and highlights a set of proactive strategies aimed at generating sustainable competitive advantage based on value-generating business practices. We focus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers for cutting-edge R&D, and new forms of cooperation and internationalization, such as open innovation in the early phases of R&D. Our findings are illustrated by cases from Europe, the US, and Asia. "One way we try to foster innovation - both the technological innovation and the organizational innovation - is to align our business objectives with our ideals." Dr. Daniel Vasella, CEO, Novartis International "Pharmaceutical innovation is in crisis. The industry will have to change both its innovation processes and its business models in order to reverse these trends and prosper in the future. Professors Gassmann, Reepmeyer and von Zedtwitz have marshalled together an impressive array of research in one volume. This book should prove to be an indispensable resource for all participants in the pharmaceutical industry." Prof. Henry Chesbrough, Executive Director, Center for Open Innovation, Haas School of Business, University of California, Berkeley "It´s time for a paradigm shift in pharmaceutical R&D. This book will tell you why." Dr. Goetz Baumann, Business Unit Manager, Hoffmann-La Roche (Germany) "This book offers a fact based, comprehensive insight to the increasing challenges of today`s drug development. Well worth reading not just for newcomers to the industry but also for industry professionals who want to understand the big picture". Dr. Pius Renner, Head of Strategic Planning and Portfolio Management in Development, Novartis Pharma .

Pharmaceutical industry --- Drugs --- Technological innovations. --- Technological innovations --- Research --- Management. --- Management --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Drug industry --- Drug trade --- Medicine industry --- Medicines industry --- Prescription medicine industry --- Chemical industry --- Medical innovations --- Economic policy. --- Pharmacy. --- Innovation/Technology Management. --- R & D/Technology Policy. --- Public Health. --- Chemistry --- Medicine --- Economic nationalism --- Economic planning --- National planning --- State planning --- Economics --- Planning --- National security --- Social policy --- Administration --- Industrial relations --- Organization --- Industrial management. --- Public health. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Business administration --- Business enterprises --- Business management --- Corporate management --- Corporations --- Industrial administration --- Management, Industrial --- Rationalization of industry --- Scientific management --- Business --- Industrial organization

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Competition, International --- Technological innovations --- Management

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Multinational work teams --- Research and development projects --- Management

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“Don’t miss out on China!” and “What are you doing about China?” Catch phrases like these are spreading among managers all over the world. Just take a brief look at the business class occupancy of flights from Europe, North America or Japan to major Chinese cities: This gives you a glimpse of how business people are attracted by steady growth rates of 6 percent to 10 percent. It also indicates how much attention is given to a market featuring 1.3 billion potential consumers and a government committed to rapidly changing the country from an agricultu- dominated developing country into one of the world’s economic powerhouses. Most of the global industrial players have had economic ties with China for decades already, but they were further strengthened after the country’s opening to the world in the early 1980s. Furthermore, China’s accession to the World Trade Or- nization is expected to catapult this already surging economy into another sphere of development.

Chemical industry --- Pharmaceutical industry --- Drug industry --- Drug trade --- Medicine industry --- Medicines industry --- Prescription medicine industry --- Pharmacology. Therapy --- Chemistry --- China --- Management. --- Chemistry. --- Pharmacy. --- Chemistry/Food Science, general. --- Physical sciences --- Administration --- Industrial relations --- Organization --- Medicine --- Drugs --- Materia medica --- Pharmacology --- 615 <510> --- 661.1 <510> --- Farmacologie. Farmaceutische wetenschappen--China --- Special chemical industries--China