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Will address an important, yet underrepresented, topic. The correlation between viruses and atherosclerosis has been a focal point of the authors’ work, for a number of years. This volume will explore the relationship between different viral strains and atherosclerosis. It will begin by describing the hypothesis and denoting the mechanisms of virus-driven atherosclerosis, then expanding on the subject by focusing on different virus strains—from Herpes, to Epstein-Barr, to the triad of Hepatitis viruses, et al—on a chapter-by-chapter basis. While there are books, albeit few, that cover particular viral strains and their relationship to cardiovascular diseases, this work will be unique in its scope by considering multiple strains of viruses, making it a repository of information on the topic; a truly comprehensive volume.
Arteriosclerosis -- Treatment. --- Atherosclerosis -- Diagnosis. --- Atherosclerosis -- Therapy. --- Viruses. --- Atherosclerosis --- Viruses --- Diseases --- Microbiology --- Arteriosclerosis --- Arterial Occlusive Diseases --- Biology --- Biological Science Disciplines --- Vascular Diseases --- Natural Science Disciplines --- Cardiovascular Diseases --- Disciplines and Occupations --- Virology --- Virus Diseases --- Medicine --- Health & Biological Sciences --- Microbiology & Immunology --- Treatment. --- Diagnosis. --- Arterial sclerosis --- Arteries --- Hardening of the arteries --- Sclerosis, Arterial --- Hardening --- Sclerosis --- Medicine. --- Immunology. --- Medical microbiology. --- Virology. --- Biomedicine. --- Medical Microbiology. --- Genetic vectors --- Microorganisms --- Mobile genetic elements --- Extrachromosomal DNA --- Arterial occlusions --- Medical virology. --- Microbiology. --- Microbial biology --- Immunobiology --- Life sciences --- Serology --- Medical microbiology --- Virus diseases
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This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
Cardiology. --- Cell receptors. --- Genetics. --- Human genetics. --- Immunology. --- Life sciences. --- Cell receptors --- Genetics --- Biology --- Receptors, Immunologic --- Diseases --- Polymorphism, Genetic --- Receptors, Cell Surface --- Genetic Variation --- Biological Science Disciplines --- Membrane Proteins --- Genetic Phenomena --- Natural Science Disciplines --- Disciplines and Occupations --- Proteins --- Phenomena and Processes --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Cardiovascular Diseases --- Receptors, Pattern Recognition --- Genomic Structural Variation --- Neoplasms --- Chemistry --- Health & Biological Sciences --- Physical Sciences & Mathematics --- Biochemistry --- Biology - General --- Receptors. --- Cancer --- Research. --- Cancer research --- Immunobiology --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Cancer research. --- Oncology. --- Proteins. --- Life Sciences. --- Cancer Research. --- Human Genetics. --- Heredity, Human --- Human biology --- Physical anthropology --- Life sciences --- Serology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Binding sites (Biochemistry) --- Cell membranes --- Oncology . --- Heart --- Internal medicine --- Tumors --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics
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Will address an important, yet underrepresented, topic. The correlation between viruses and atherosclerosis has been a focal point of the authors’ work, for a number of years. This volume will explore the relationship between different viral strains and atherosclerosis. It will begin by describing the hypothesis and denoting the mechanisms of virus-driven atherosclerosis, then expanding on the subject by focusing on different virus strains—from Herpes, to Epstein-Barr, to the triad of Hepatitis viruses, et al—on a chapter-by-chapter basis. While there are books, albeit few, that cover particular viral strains and their relationship to cardiovascular diseases, this work will be unique in its scope by considering multiple strains of viruses, making it a repository of information on the topic; a truly comprehensive volume.
General microbiology --- Immunology. Immunopathology --- Medical microbiology, virology, parasitology --- Pathological biochemistry --- Human medicine --- immunologie --- medische microbiologie --- medische biochemie --- medische virologie --- biochemie --- biomedische wetenschappen --- microbiologie --- virologie
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This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
Histology. Cytology --- Molecular biology --- Biology --- Immunology. Immunopathology --- Oncology. Neoplasms --- Human genetics --- Pathology of the circulatory system --- immunologie --- patroonherkenning --- medische genetica --- genomics --- biologie --- genetica --- oncologie --- cardiologie --- cytologie --- moleculaire biologie
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Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of research on the most promising aspects of this topic. The structure and presentation of the work is very understandable and clear with attention to detail maintained throughout. There are multiple illustrations throughout to help in comprehending and rem.
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This collection represents certain discoveries that were made in evolutionary and genomic microbiology during the recent ten years. We attempted to shed light on topical issues of microbial evolution and microbiome biology. In our eyes, these articles are of an excellent quality and may be helpful both for casual readers and for specialists in the field.
Human microbiome --- human mycobiome --- gut microbiome --- domains of life --- brain-gut-microbe axis --- oral microbiome --- Human Ecology --- evolution --- genomic microbiology --- evolutionary microbiology
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The group of pattern recognition receptors (PRRs) includes families of Toll-like receptors (TLRs), NOD-like receptors (NLRs), C-type lectin receptors (CLRs), RIG-I-like receptors (RLRs), and AIM-2-like receptors (ALRs). Conceptually, receptors constituting these families are united by two general features. Firstly, they directly recognize common antigen determinants of virtually all classes of pathogens (so-called pathogen-associated molecular patterns, or simply PAMPs) and initiate immune response against them via specific intracellular signaling pathways. Secondly, they recognize endogenous ligands (since they are usually released during cell stress, they are called damage-associated molecular patterns, DAMPs), and, hence, PRR-mediated immune response can be activated without an influence of infectious agents. So, pattern recognition receptors play the key role performing the innate and adaptive immune response. In addition, many PRRs have a number of other vital functions apart from participation in immune response realization. The fundamental character and diversity of PRR functions have led to amazingly rapid research in this field. Such investigations are very promising for medicine as immune system plays a key role in vast majority if not all human diseases, and the process of discovering the new aspects of the immune system functioning is rapidly ongoing. The role of Toll-like receptors in cancer was analyzed in certain reviews but the data are still scattered. This collection of reviews systematizes the key information in the field.
Toll-Like Receptors --- C-type lectin receptors --- nod-like receptors --- DNA Repair --- Pattern Recognition Receptors --- Inflammation --- RIG-I-like receptors --- Autophagy --- Cancer --- Apoptosis
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This collection represents certain discoveries that were made in evolutionary and genomic microbiology during the recent ten years. We attempted to shed light on topical issues of microbial evolution and microbiome biology. In our eyes, these articles are of an excellent quality and may be helpful both for casual readers and for specialists in the field.
Human microbiome --- human mycobiome --- gut microbiome --- domains of life --- brain-gut-microbe axis --- oral microbiome --- Human Ecology --- evolution --- genomic microbiology --- evolutionary microbiology
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The group of pattern recognition receptors (PRRs) includes families of Toll-like receptors (TLRs), NOD-like receptors (NLRs), C-type lectin receptors (CLRs), RIG-I-like receptors (RLRs), and AIM-2-like receptors (ALRs). Conceptually, receptors constituting these families are united by two general features. Firstly, they directly recognize common antigen determinants of virtually all classes of pathogens (so-called pathogen-associated molecular patterns, or simply PAMPs) and initiate immune response against them via specific intracellular signaling pathways. Secondly, they recognize endogenous ligands (since they are usually released during cell stress, they are called damage-associated molecular patterns, DAMPs), and, hence, PRR-mediated immune response can be activated without an influence of infectious agents. So, pattern recognition receptors play the key role performing the innate and adaptive immune response. In addition, many PRRs have a number of other vital functions apart from participation in immune response realization. The fundamental character and diversity of PRR functions have led to amazingly rapid research in this field. Such investigations are very promising for medicine as immune system plays a key role in vast majority if not all human diseases, and the process of discovering the new aspects of the immune system functioning is rapidly ongoing. The role of Toll-like receptors in cancer was analyzed in certain reviews but the data are still scattered. This collection of reviews systematizes the key information in the field.
Toll-Like Receptors --- C-type lectin receptors --- nod-like receptors --- DNA Repair --- Pattern Recognition Receptors --- Inflammation --- RIG-I-like receptors --- Autophagy --- Cancer --- Apoptosis
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The group of pattern recognition receptors (PRRs) includes families of Toll-like receptors (TLRs), NOD-like receptors (NLRs), C-type lectin receptors (CLRs), RIG-I-like receptors (RLRs), and AIM-2-like receptors (ALRs). Conceptually, receptors constituting these families are united by two general features. Firstly, they directly recognize common antigen determinants of virtually all classes of pathogens (so-called pathogen-associated molecular patterns, or simply PAMPs) and initiate immune response against them via specific intracellular signaling pathways. Secondly, they recognize endogenous ligands (since they are usually released during cell stress, they are called damage-associated molecular patterns, DAMPs), and, hence, PRR-mediated immune response can be activated without an influence of infectious agents. So, pattern recognition receptors play the key role performing the innate and adaptive immune response. In addition, many PRRs have a number of other vital functions apart from participation in immune response realization. The fundamental character and diversity of PRR functions have led to amazingly rapid research in this field. Such investigations are very promising for medicine as immune system plays a key role in vast majority if not all human diseases, and the process of discovering the new aspects of the immune system functioning is rapidly ongoing. The role of Toll-like receptors in cancer was analyzed in certain reviews but the data are still scattered. This collection of reviews systematizes the key information in the field.
Toll-Like Receptors --- C-type lectin receptors --- nod-like receptors --- DNA Repair --- Pattern Recognition Receptors --- Inflammation --- RIG-I-like receptors --- Autophagy --- Cancer --- Apoptosis
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