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DNA Repair and Replication contains an up-to-date review of general principles of DNA replication and an overview of the multiple pathways involved in DNA repair. Specific DNA repair pathways, including base-excision repair, light-dependent direct reversal of UV-damage, nucleotide-excision repair, transcription-coupled repair, double-strand break repair, and mismatch repair, are each discussed in separate chapters.Selected Contents:-Base Excision Repair-Eukaryotic DNA Mismatch Repair-Double Strand Break Repair-Functions of DNA Polymerases-Somatic Hypermutation: A M
DNA repair. --- DNA replication. --- Chromosomal DNA replication --- DNA --- Replication of DNA --- Deoxyribonucleic acid repair --- Repair, DNA --- Repair mechanisms in DNA --- Biochemical genetics --- Antimutagens --- Replication --- Synthesis
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Time-Dependent Reliability Theory and Its Applications introduces the theory of time-dependent reliability and presents methods to determine the reliability of structures over the lifespan of their services. The book contains state-of-the-art solutions to first passage probability derived from the theory of stochastic processes with different types of probability distribution functions, including Gaussian and non-Gaussian distributions and stationary and non-stationary processes. In addition, it provides various methods to determine the probability of failure over time, considering different failure modes and a methodology to predict the service life of structures. Sections also cover the applications of time-dependent reliability to prediction of service life and development of risk cost-optimized maintenance strategy for existing structures. This new book is for those who wants to know how to predict the service life of a structure (buildings, bridges, aircraft structures, etc.) and how to develop a risk-cost, optimized maintenance strategy for these structures.
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