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Aromatic compounds --- Textile fibers, Synthetic --- Congresses. --- Congresses --- Textile fibers, Synthetic - Congresses --- Aromatic compounds - Congresses

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Slope Stability Analysis by the Limit Equilibrium Method: Fundamentals and Methods presents basic principles for the safe design of constructed or natural earth slopes. The limit equilibrium method is the most common approach for analyzing slope stability in both two and three dimensions. This method identifies potential failure mechanisms and derives factors of safety for a particular geotechnical situation. It is an appropriate choice for assessing the stability of retaining walls, shallow and deep foundations, earth and rock dams, surface mining sites, and potential landslides. The fundamentals of slope stability encompass slope movements and methods for stability analysis, mechanics of slope failure and factors of safety, laboratory and field methods to determine the shear strength of soils, estimation of phreatic surfaces, and remedial measures for correcting slides. Methods of stability analysis cover simple formulas for determining the factor of safety for plane failures, stability charts, methods of slices for two-dimensional analysis, three-dimensional analysis techniques, and reliability of slope design. An appendix provides a preview of a companion product, LEAME Software and User's Manual: Analyzing Slope Stability by the Limit Equilibrium Method, a computer program for performing the slope stability analysis presented in this work. The clear presentation of the principles of slope stability analysis ensures that this work will be a frequently consulted reference for practicing engineers. The wealth of worked examples and problem sets make this a suitable textbook for senior and graduate students in soil mechanics and geotechnical engineering.

Slopes (Soil mechanics) --- Slope stability --- Failure analysis --- Limit equilibrium --- Limit analysis --- Water table --- Three-dimensional analysis --- Safety --- Shear strength

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LEAME Software and User's Manual: Analyzing Slope Stability by the Limit Equilibrium Method provides a PC-based software program for performing slope stability analyses, along with supporting documentation. LEAME (limit equilibrium analysis of multilayered earthworks) is the most recent version of software, previously known as REAME (rotational equilibrium analysis in multilayered embankments). Developed by Yang H. Huang at the University of Kentucky and thoroughly tested in both engineering firms and classrooms, LEAME determines the factors of safety for both two- and three-dimensional slopes and contains many new features not available elsewhere to solve practical problems in slope stability. The software is accompanied by a PDF user's manual with detailed instructions for installing and operating LEAME. The manual explains the input parameters in each data entry form. It also describes the features available for two- and three-dimensional analysis, illustrated with sample problems and worked examples. Data files for the examples are also included. The application of LEAME to problems of spoil and waste disposal in surface mining is covered in detail, including worked examples. The software and user's manual are offered in conjunction with a companion volume, Slope Stability Analysis by the Limit Equilibrium Method: Fundamentals and Methods, which presents principles and methods for using the limit equilibrium method in analyzing slopes. In combination, the book, software, and user's manual provide practicing engineers, engineering professors, and students with a complete set of tools for understanding and analyzing challenges in slope stability. The LEAME software can be used on any PC with Windows 95 or higher. It is not available for other operating systems. Software is supplied under a license that restricts usage to a single computer. Multi-user/multisite licenses are available by inquiring at ascelibraryasce.org or calling 1-800-548-2723.

Computer software --- Slope stability --- Limit equilibrium --- Limit analysis --- Three-dimensional analysis --- Licensure and certification --- Computers --- Earthwork

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The purpose of this book is to highlight some of latest developments and applications of CRISPR, RNA, and DNA to treat diseases ranging from cancers to cardiovascular and degenerative disorders. It also features innovations of the delivery methods for nucleic acids ranging from nanodevices made from DNA and pseudo amino acids to viral vectors. This is an ideal book for academics, clinicians, and students interested in gene therapy.

Human biochemistry --- Pharmacology. Therapy --- Human genetics --- Biotechnology --- medische biochemie --- medische genetica --- bio-engineering --- farmacologie --- biotechnologie