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The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other mechanisms including effects on glucose metabolism, body fat distribution, blood pressure, inflammation, and heart rate. Furthermore, studies evaluating single fatty acids have challenged the simplistic view of shared health effects within fatty acid groups categorized by degree of saturation. In addition, investigations of endogenous fatty acid metabolism, including genetic studies of fatty acid metabolizing enzymes, and the identification of novel metabolically derived fatty acids have further increased the complexity of fatty acids’ health impacts. This Special Issue aims to include original research and up-to-date reviews on genetic and dietary modulation of fatty acids, and the role and function of dietary and metabolically derived fatty acids in cardiometabolic health.
coronary artery disease --- n-6 fatty acids --- ischemic heart disease --- n-3 fatty acids --- body weight --- alternatively activated macrophages --- type 2 cytokines --- children --- medium-chain triglyceride --- fat --- omega-3 PUFA --- substitution models --- obesity --- EETs --- arachidonic acid --- blood pressure --- Genome-wide association study (GWAS) --- antioxidant --- Mediterranean diet --- Insulin sensitivity --- PUFA --- n-3 PUFA --- long-chain triglyceride --- fish oil --- omega 3 --- CAD --- adipose tissue --- FADS --- blood lipids --- hemodynamics --- genotype --- erucic acid --- klotho --- CYP450 eicosanoids --- cardiometabolic disease --- fibrosis --- desaturase --- EEQs --- cohort study --- lipid metabolism --- fatty acid --- metabolic disease --- epidemiology --- omega-3 --- inflammation --- docosapentaenoic acid --- omega-6 PUFA --- type 2 diabetes mellitus --- diet --- CKD --- human --- perivascular adipose tissue --- seafood --- cardiovascular disease --- prospective cohort study --- linoleic acid --- low-fat diet --- conjugated fatty acids --- furan fatty acids --- unsaturated fat --- statins --- fish --- cholesterol ester --- CHD --- COPD
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Proceedings of the GeoHunan International Conference II: Emerging Technologies for Design, Construction, Rehabilitation, and Inspection of Transportation Infrastructure, held in Hunan, China, June 9-11, 2011. This Geotechnical Special Publication contains 42 papers addressing contemporary geotechnical subjects. Topics include: physical, numerical, and constitutive modeling of soil behavior; soil behavior and laboratory testing; soils and rock instrumentation, behavior, and modeling; and forensic engineering.
Soil properties --- Instrumentation --- Soil tests --- Rocks --- Material properties --- Numerical models --- Infrastructure construction --- Geotechnical engineering --- Soil properties --- Instrumentation --- Soil tests --- Rocks --- Material properties --- Numerical models --- Infrastructure construction --- Geotechnical engineering
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Selected papers from the proceedings of the Geo-Hubei 2014 International Conference on Sustainable Civil Infrastructure, held in Yichang, Hubei, China, July 20-22, 2014. Sponsored by the China Three Gorges University, the Committee on Sustainability of ASCE, and the Geo-Institute of ASCE. Geotechnical Special Publication 245 contains 13 peer-reviewed papers covering innovative and sustainable use of geomaterials and geosystems. Topics include: reuse of geomaterials; in-situ testing methods for site characterization; design and quality control of earth structures; and dynamic behavior of soils and foundations. This GSP will be of interest to both researchers and practitioners in geotechnical engineering.
Sustainable development --- Geomaterials --- Innovation --- Geotechnical engineering --- Soil dynamics --- Professional societies --- Field tests --- Foundation design --- Sustainable development --- Geomaterials --- Innovation --- Geotechnical engineering --- Soil dynamics --- Professional societies --- Field tests --- Foundation design
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