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The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.* Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for

Kidneys --- Endocrine glands --- Diseases --- Endocrine aspects. --- Diseases. --- Clinical endocrinology --- Endocrine diseases --- Hormonal disorders --- Abdomen --- Urinary organs --- Nephrology

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Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. This book is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science. Clinical and translational science are fields devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. This book is designed as the most authoritative and up-to-date resource for the broad range of investigators in various medical specialties taking on the challenge of clinical and translational science. Prepared with an international perspective, Clinical and Translational Science begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, legal, social, and ethical issues of clinical research are discussed concluding with a discussion of future prospects to provide readers with a comprehensive view of this developing area of science. Discusses practical biological, physiological, cellular, and therapeutic applications for one of the fastest growing fields in private practice and academic medicine. Includes contributions from international leaders providing insight into background and future understanding for clinical and translational science. Presents the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research.

Human medicine --- Biotechnology

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"Textbook of Nephro-Endocrinology, Second Edition, continues to be the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism. Changes to this edition include new chapters focused on hypercalcemia/hypocalcemia and the interaction of dialysis, chronic renal disease, and endocrine diseases. All chapters have been updated to include more preclinical data and more tables and schema that help translate this data into clinical recommendations. The section on hormones and renal insufficiency discusses insulin/diabetes, growth hormone, sex steroids, thyroid hormone, acid-base disturbances, and pregnancy"--Publisher's description.

Kidneys --- Nephrology. --- HEALTH & FITNESS / Diseases / General. --- MEDICAL / Clinical Medicine. --- MEDICAL / Diseases. --- MEDICAL / Evidence-Based Medicine. --- MEDICAL / Internal Medicine. --- Kidney Diseases --- Endocrine System Diseases --- Hormones --- Diseases --- Endocrine aspects --- Diseases. --- physiopathology. --- physiology. --- Kidney Diseases.