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Northern Ireland --- Irlande du Nord --- Politics and government --- Historiography --- Social conditions --- Conditions sociales --- #KVHA:Noord-Ierland --- Northern Ireland - Politics and government - 1969- - Historiography. --- Historiography.

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Church and state --- History

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A collection of vital information that answers readers' most pressing questions about how age impacts their bodies.Many people are embarrassed to bring their everyday health anxieties to their physicians or even to ask for advice from family and friends. They might think that depression, failing eyesight, memory loss, and other difficulties that change their quality of life are normal because of their age. This is where Is This Normal? steps in and lets readers know whether or not these changes should be a concern or an expected part of aging.With compassion, reassurance, and friendly guidance, Dr. John Whyte, chief medical expert at the Discovery Channel, provides the essential tools for dealing with the common health issues that arise as we get older, proving that you can stay active and healthy at any age."Using soothing language and a gentle sense of humor, Whyte . . . tries to separate fact from rumor." --The Washington Post"All your embarrassing aging questions answered--finally!"--Vital Juice

Middle-Aged Persons --- Aging --- Self-Help --- Social Science

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Highly praised in its first edition, Clinical Evaluation of Medical Devices: Principles and Case Studies, Second Edition has been expanded and updated to include the many innovations and clinical research methods that have developed since the first edition, as well as current information on the regulatory, legal, and reimbursement environment for medical devices. The book's deeply experienced authors summarize the key principles and approaches employed in medical device clinical trials and illustrate their uses in a revealing series of detailed, real-world case studies. Highlights include new information on the requirements and process for gaining reimbursement from Medicare and private insurers on new products-including case studies of research specifically designed for this purpose-and new statistical methods applied to medical device trials. Additional case studies provide examples of combination products, three-phase development models (i.e., feasibility, FDA approval, and Medicare reimbursement), and novel study designs. The cases demonstrate a wide range of designs that have been successfully applied to many different research problems, as well as to a variety of therapeutic or diagnostic products. Authoritative and highly practical, Clinical Evaluation of Medical Devices: Principles and Case Studies, Second Edition, provides a gold-standard resource for clinical professionals and regulatory specialists working at the forefront of new therapeutics, diagnostics, and medical device development and marketing today.

Medical instruments and apparatus --- Clinical trials. --- Evaluation. --- Controlled clinical trials --- Patient trials of new treatments --- Randomized clinical trials --- Trials, Clinical --- Clinical medicine --- Human experimentation in medicine --- Apparatus, Medical --- Instruments, Medical --- Medical apparatus --- Medical devices --- Medical products --- Medicine --- Biomedical engineering --- Medical supplies --- Scientific apparatus and instruments --- Research --- Apparatus --- Equipment and supplies --- Instruments

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