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The Whipple Museum in Cambridge contains one of the most important existing collections in the history and philosophy of science and has played a key role in teaching and research within those subjects. Founded in 1944 with funding from Robert Stuart Whipple, formerly of the Cambridge Scientific Instrument Company, the Museum aims to preserve the material culture of science through its collections, to document and provide access to those collections, and to interpret and research the material culture and associated practices of past science. This volume brings together 23 essays and 85 illustrations which chart the Museum's history; examine its role and influence within the University of Cambridge and the study of the subject more widely; and focus on a range of particular scientific instruments in the collection, drawing out their broader historical significance and associations.