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This dissertation explores the sex differences in cardiovascular disease (CVD) and the effects of exercise interventions. It focuses on understanding the proteomic differences in atherosclerotic plaques between men and women, highlighting that men tend to develop plaques with greater inflammation and vulnerability, while women show a more stable plaque phenotype. The study also evaluates the impact of resistance training on women, demonstrating potential benefits in reducing CVD risk factors such as iron levels, lipids, and inflammation. The research aims to provide insights into the biological differences in CVD development and suggests exercise as a preventive strategy, particularly in women.

Atherosclerosis. --- Proteomics. --- Atherosclerosis --- Proteomics