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This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.

Pharmacology. --- Cardiology. --- Pharmacotherapy. --- Cardiac surgery. --- Pharmacology/Toxicology. --- Cardiac Surgery. --- Cardiac surgery --- Heart --- Open-heart surgery --- Drug therapy --- Pharmacotherapy --- Therapeutics --- Drugs --- Pharmacology --- Internal medicine --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Pharmacy --- Diseases --- Surgery --- Physiological effect --- Coronary heart disease --- Treatment. --- Malalties coronàries --- Quimioteràpia --- Cirurgia cardíaca --- Cirurgia del cor --- Cirurgia cardiovascular --- Cateterisme cardíac --- Derivació cardiopulmonar --- Trasplantament cardíac --- Anestèsia en cardiologia --- Farmacoteràpia --- Immunoquimioteràpia --- Terapèutica medicamentosa --- Terapèutica per agents químics (Medicina) --- Tractament amb medicaments --- Tractament per agents químics (Medicina) --- Us terapèutic dels medicaments --- Terapèutica --- Administració de medicaments --- Antibiòtics --- Diürètics --- Fotoquimioteràpia --- Pirogens --- Psicofarmacologia --- Prescripció de medicaments --- Quimioteràpia del càncer --- Utilització de medicaments --- Farmacologia --- Medicaments --- Arterioesclerosi coronària --- Cardiopatia isquèmica --- Coronariopaties --- Isquèmia miocardíaca --- Malalties de les artèries coronàries --- Malalties cardiovasculars --- Angina de pit --- Infart de miocardi

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History of human medicine --- Pharmacology. Therapy --- Pathology of the circulatory system --- Surgery --- farmacotherapie --- farmacologie --- cardiologie --- hartchirurgie

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This book examines recent research on designing online charging and discharging strategies for mobile electric vehicles (EVs) in smart grid. First, the architecture and applications are provided. Then, the authors review the existing works on charging and discharging strategy design for EVs. Critical challenges and research problems are identified. Promising solutions are proposed to accommodate the issues of high EV mobility, vehicle range anxiety, and power systems overload. The authors investigate innovating charging and discharging potentials for mobile EVS based on real-time information collections (via VANETS and/or cellular networks) and offer the power system adjustable load management methods.  Several innovative charging/discharging strategy designs to address the challenging issues in smart grid, i.e., overload avoidance and range anxiety for individual EVs, are presented. This book presents an alternative and promising way to release the pressure of the power grid caused by peak-time EV charging demand. Mobile Electric Vehicles: Online Charging and Discharging provides valuable insights on charging/ discharging strategy design for mobile EVs and the power system management in a smart grid. The authors’ findings indicate that the proposed strategies considerably outperform the traditional EV charging strategies without real-time collections on the metrics of the overall energy utilizat ion, the average EV travel cost and the number of successfully charged EVs. Research and graduate students who are working on smart grid and vehicular communication will find this book a valuable resource.  Customs and systems operators will also find this book useful. .

Electrical Engineering --- Electrical & Computer Engineering --- Engineering & Applied Sciences --- Electric vehicles --- Electric automobiles --- Smart power grids. --- Power supply. --- Automobiles, Electric --- Electric cars --- EVs (Electric vehicles) --- Vehicles, Electric --- Smart grids (Electric power distribution) --- Grids, Smart power --- Power grids, Smart --- Electric power distribution --- Automobiles --- Motor vehicles --- Automation --- Telecommunication. --- Computer Communication Networks. --- Information systems. --- Communications Engineering, Networks. --- Information Systems and Communication Service. --- Electric communication --- Mass communication --- Telecom --- Telecommunication industry --- Telecommunications --- Communication --- Information theory --- Telecommuting --- Electrical engineering. --- Computer communication systems. --- Computers. --- Automatic computers --- Automatic data processors --- Computer hardware --- Computing machines (Computers) --- Electronic brains --- Electronic calculating-machines --- Electronic computers --- Hardware, Computer --- Computer systems --- Cybernetics --- Machine theory --- Calculators --- Cyberspace --- Communication systems, Computer --- Computer communication systems --- Data networks, Computer --- ECNs (Electronic communication networks) --- Electronic communication networks --- Networks, Computer --- Teleprocessing networks --- Data transmission systems --- Digital communications --- Electronic systems --- Information networks --- Telecommunication --- Cyberinfrastructure --- Electronic data processing --- Network computers --- Electric engineering --- Engineering --- Distributed processing

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China --- China --- China --- China --- China --- Economic conditions --- Economic conditions --- Social conditions --- Social conditions --- Social life and customs

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