Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This is the first book to bring together the history, theory, mathematical approach, measurement details and limitations of the Multiple Inert Gas Elimination Technique (MIGET) and a summary of the global literature on its application in health and disease over the last 40 years. Up to the early 1970's, and despite substantial research carried out by leaders in respiratory physiology, it was not possible to measure the most important and most complex component of gas exchange in the lung: ventilation/perfusion (VA/Q) heterogeneity. Building on that earlier research, MIGET was developed to overcome this large gap in our understanding of the most important function of the lung. Just as CT and MRI make use of multiple, simultaneous imaging views to reconstruct the underlying anatomy spatially, MIGET uses the simultaneous exchange of six inert gases with differing blood solubility to reconstruct the functional distribution of VA/Q ratios. While the basic physiological principle of MIGET is straightforward, using inert gas exchange data to construct the VA/Q distribution requires complicated mathematics along with the ability to simultaneously measure the exchange of six foreign gases present in just parts per million or less. This unique book is a valuable resource for anyone interested in how the lung works.

Physiology of the respiratory system --- Human physiology --- Social medicine --- Pathology of the respiratory system --- Recreation. Games. Sports. Corp. expression --- MRI (magnetic resonance imaging) --- toxicologie --- pneumologie --- sportgeneeskunde --- fysiologie

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies. This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include: Epigenetic Variations in Hypoxia High Altitude Adaptation Hypoxia and Sleep Hypoxia and the Brain Molecular Oxygen Sensing Physiological Responses to Hypoxia Dr. Robert Roach is the Director of the Altitude Research Center at the University of Colorado. He specializes in the study of physiological adaptations by humans to high altitude, with a recent emphasis on the genomic responses to allow humans to thrive in hypoxia. Dr. Peter Wagner is a Distinguished Professor of Medicine and Bioengineering at the University of California, San Diego. His research addresses the theoretical and experimental basis of oxygen transport and its limitations in the lungs and skeletal muscles in health and disease. Dr. Peter Hackett is a world-renowned high altitude expert and altitude research pioneer. He is a leading authority on altitude illness, high altitude climbing, wilderness medicine, and the effects of altitude on people living and working in the mountains.

Pneumology. --- Anoxemia. --- Anoxaemia --- Anoxhemia --- Anoxia --- Hypoxemia --- Hypoxia (Hematology) --- Oxygen deficiency in the blood --- Altitude, Influence of --- Asphyxia --- Oxygen --- Oxygen in the body --- Physiological effect --- Human physiology. --- Immunology. --- Neurosciences. --- Human Physiology. --- Pneumology/Respiratory System. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Immunobiology --- Life sciences --- Serology --- Human biology --- Physiology --- Human body --- Respiratory organs—Diseases. --- Respiratory organs --- Diseases. --- Respiratory diseases

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

General biochemistry --- Human physiology --- Anesthesiology --- Pathology of the circulatory system --- Neuropathology --- neurologie --- farmacologie --- biochemie --- anesthesie --- cardiologie --- fysiologie

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies. This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include: Epigenetic Variations in Hypoxia High Altitude Adaptation Hypoxia and Sleep Hypoxia and the Brain Molecular Oxygen Sensing Physiological Responses to Hypoxia Dr. Robert Roach is the Director of the Altitude Research Center at the University of Colorado. He specializes in the study of physiological adaptations by humans to high altitude, with a recent emphasis on the genomic responses to allow humans to thrive in hypoxia. Dr. Peter Wagner is a Distinguished Professor of Medicine and Bioengineering at the University of California, San Diego. His research addresses the theoretical and experimental basis of oxygen transport and its limitations in the lungs and skeletal muscles in health and disease. Dr. Peter Hackett is a world-renowned high altitude expert and altitude research pioneer. He is a leading authority on altitude illness, high altitude climbing, wilderness medicine, and the effects of altitude on people living and working in the mountains.

Immunology. Immunopathology --- Physiology of the respiratory system --- Human physiology --- Pathological biochemistry --- Pathology of the respiratory system --- Neuropathology --- Human medicine --- immunologie --- klinische chemie --- medische biochemie --- neurologie --- biochemie --- biomedische wetenschappen --- pneumologie --- fysiologie --- moleculaire biologie

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The hypoxia volumes will focus on cutting edge research at the interface of hypoxia and biomedicine. Hypoxia is a constant threat to the human body and its vital organs throughout life. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. The International Hypoxia Symposia was founded to enable scientists, clinicians, physiologists, immunologists, mountaineers and other interested individuals to share their experiences of the situations associated with oxygen lack and the adaptations that allow us to survive. The mission of the International Hypoxia Symposia is to present cutting edge, sophisticated research at the very highest levels into the many effects of hypoxia on humans and animals in health and disease.

Human biochemistry --- Immunology. Immunopathology --- Human physiology --- Neuropathology --- immunologie --- medische biochemie --- neurologie --- biochemie --- fysiologie