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ISBN: 9786611145255 1281145254 019856922X 0191524581 1429469935 9780191524585 9781429469937 0198569238 9780198569237 9780198569220 0198569238 9780198569237 Year: 2007 Publisher: Oxford : Oxford University Press,
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Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol
Book
ISBN: 0875868878 9780875868875 9780875868851 0875868851 9780875868868 087586886X Year: 2011 Publisher: New York Algora Pub.
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The American Technological Challenge - Stagnation and Decline in the 21st Century refutes the myth that we live in the most innovative of times. Inventions themselves are only one of the factors that determine the technological fate of a society. Sometimes, inventions are adopted, and eagerly; sometimes not. The history of technological progress, and the historical and societal factors that impel or restrain the adoption of inventions, are explored in the book. New, life-changing inventions have become rare and in spite of ample vocal support of innovation, an increasingly complacent society h
Culture. --- Politics and culture. --- Politics. --- Technology and civilization --- Technology --- History
Dissertation
ISBN: 9090015604 Year: 1987 Publisher: 's-Gravenhage Pasmans
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DNA Replication --- Aging --- DNA Repair --- Mutation --- Fibroblasts --- Ultraviolet Rays --- genetics --- radiation effects --- metabolism
ISBN: 0137914504 Year: 1993 Publisher: New York : E. Horwood,
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New technology for analyzing complex genomes is an important area of modern molecular biosciences. This book focuses on a recently developed genome scanning method, termed two-dimensional 2-D DNA typing, which is based on a combination of two independent electrophoretic separation principles. When separation according to size is coupled to separation according to base-pair composition, complex genomes can be resolved in a number of DNA fragments. These fragments or subsets can be visualized, for example, by hybridization analysis with specific probes. Genome scanning by 2-D DNA typing finds applications in many areas, such as linkage and association studies for identifying genetic traits in humans, animals and plants, studies on genetic instabilities in cancers, classification studies in bacteria and other lower organisms, studies on human mutation rates, and the identification of mutations in large genes.
DNA --- Electrophoresis, Gel, Two-Dimensional --- Two-dimensional electrophoresis --- ADN --- Electrophorèse bidimensionnelle --- analysis --- methods --- Analysis --- Analyse --- Two-dimensional electrophoresis. --- Electrophoresis, gel, two-dimensional --- Dna --- Analysis. --- Methods. --- analysis. --- methods.
ISBN: 0897667301 0897667298 9780897667296 9780897667302 Year: 1992 Volume: 663 Publisher: New York (N.Y.) : New York academy of sciences,
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Aging --- Cells --- Cellular immunity --- Molecular aspects --- Congresses. --- immunology --- congresses. --- physiology --- Organisms --- Cytology --- Age --- Ageing --- Senescence --- Developmental biology --- Gerontology --- Longevity --- Age factors in disease --- Cell-mediated immunity --- Cellular immunology --- Clonal selection theory --- Immune response --- Immunity --- Molecular aspects&delete& --- Congresses --- Aging&delete& --- Physiological effect --- Aging - Molecular aspects - Congresses. --- Cellular immunity - Congresses. --- Cells - Aging - Congresses.
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