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Music --- oude muziek --- Matelart, Johannes
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Introduction: This study aims to find a standardized method to describe the changes in the arch perimeter, so it could be added to the protocol of the expansion study. The previous study aimed to investigate the effect of interceptive orthodontics on the dental arch characteristics after slow maxillary expansion. No method to determine the arch perimeter has been added yet to the existing protocol. Material and method: A literature review was conducted for a standardized method to determine the arch perimeter before and after expansion. Furthermore, the influence of the inclination of the upper incisors on the arch perimeter was investigated through a literature review to determine whether this should be taken into account for a standardized method for measuring the arch perimeter. These findings were gained by measuring the difference of the arch perimeter and the inclination of the upper incisors before and after treatment. Pearson’s correlation was used to check whether there is a correlation present with the help of SPSS statistics. The test group consists of 9 individuals who had a cervical headgear as treatment to distalize the molars, so the incisors have the chance to change the inclination. Results: Fifteen different methods were found to determine the arch perimeter. These were just an estimation of the arch perimeter and did not take into account the different criteria which could have an influence on the arch perimeter. Only 7 relevant articles about the relationship between the inclination and the arch perimeter were found, they were all unreliable. The control measurements showed no correlation between the change of the arch perimeter and the change of the inclination. This result was not significant due to the small sample size. Conclusion: It can be concluded that no standardized method exists. So, it is not possible to add one to the protocol of the expansion study. The research for the effect of the inclination of the upper incisors on the arch perimeter shows no reliable results.
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Objective: The aim of this study was to analyse the thrombophilia population that underwent oral and/or maxillofacial surgery at our centre. Study design: We performed a retrospective analysis of patients with hereditary or acquired thrombophilia who had undergone oral/maxillofacial surgery between 01/01/2000 and 31/12/2019. Data regarding demographic and patient characteristics, surgical treatment modalities, antithrombotic therapies, and complications were analysed. Results: A total of 76 eligible patients (26 male; 50 female) were included in this study, with a mean follow-up period of 3.8 months (range 0-51 months). The mean age at time of surgery was 44.7±19.4 years. Seven different hereditary and acquired thrombophilia were identified: factor V Leiden (n=31; 40.8%), prothrombin G2021 A mutation (n=5; 6.6%), protein C deficiency (n=4; 5.3%), protein S deficiency (n=11; 14.5%), antiphospholipid syndrome (n=10; 13.2%), hyperhomocysteinemia (n=8; 10.5%), and elevated factor VIII (n=2; 2.6%). Complications occurred in 9 patients (11.8%), and included postoperative infections (n=6; 7.9%) and postoperative bleeding (n=3; 3.9%). Conclusion: Our data suggest that oral and/or maxillofacial surgery in patients with a confirmed diagnosis of thrombophilia is not associated with a burden of thrombosis or high complication rates. Furthermore, we formulated a guideline for preoperative antithrombotic therapy for thrombophilia patients undergoing oral and/or maxillofacial surgery.
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Introduction: End-stage temporomandibular joint (TMJ) disease is associated with significant morbidity and reduction in quality of life (QoL). In recent years, TMJ replacement surgery with alloplastic prosthesis has gained popularity as an effective approach for this selected patient group. Although initial data show favourable functional results, there is a lack of prospective data and subjective outcomes. The purpose of this study is to assess functional outcomes and patient- reported QoL after TMJ replacement surgery with a custom-made alloplastic prosthesis. Methods: Three questionnaires and a visual-analogue scale were used to assess patient-reported subjective outcomes and QoL in a prospective study. Furthermore, clinical data regarding jaw function were assessed as well. Results: Six patients (6 females, 0 males) with a mean age at time of surgery of 48.2±14.7 years (range 25-60 years) were included in this study. Five patients received a unilateral alloplastic prosthesis and 1 patient underwent bilateral joint replacement surgery. Significant improvements were found for pain (VAS-score) (p=0.0227), maximum interincisal opening (p=0.0098) and eating (p=0.0261) after TMJ replacement surgery. Furthermore, significant improvements were found for stress levels (p=0.0059), sleep quality (p=0.0125) and the ability to perform daily activities (p=0.0099). In addition, patients reported less discomfort due to pain postoperatively (p=0.0003) and an improved TMJ-related QoL (p=0.0312) and overall QoL (p=0.0125). Conclusion: In conclusion, TMJ replacement surgery with a custom-made alloplastic prosthesis is a safe and effective approach for patients with end-stage TMJ-disease. In addition to improved objective clinical outcomes, patient-reported subjective measurements and QoL seem to improve as well after TMJ replacement surgery.
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Approximately one in 5,600 to one in 100,000 infants is affected by a craniofacial syndrome. Up to now there are greater than 500 different syndromes described in literature. Because of the wide spectrum of syndromes and their rarity there is no clear consensus on a general classification, the treatment and the ideal window for operative intervention. The aim of this study was to get an overview of the craniofacial syndrome population at the UZ Leuven and to investigate whether there is an evolution between the periods 2000-2005 and 2010-2015 concerning the type of syndromes and the treatment received. A retrospective analysis was submitted by a search of electronic medical records with the following strings: “syndromen”, “syndroom van”, “sekwentie”, “sequentie”, “ziekte van”. Subsequently a statistical and data-analysis was performed. This search yielded a total of 2,623 results. After matching the inclusion criteria, 125 eligible patients, affected by 44 different syndromes were validated by the author and her promotor. In the first period, 55 patients were seen, as compared to 70 in the second period. The counts of all syndromes were substantially different (p<0.001) between the two time intervals. 6 patients in the first period and zero patients in the second period had a craniosynostosis associated syndrome. Regarding the received treatment, a statistically significant decrease over time is seen for cleft surgery and orthodontic treatment (χ2= 11.49, p < 0.001 and χ2= 12.73, p <0.001 respectively). No statistically significant differences were found concerning the treatment timing. Because the results showed a great number of syndromes with a limited number of patients for the distinct syndromes, it is not possible to draw firm conclusions. Further research is needed with a larger patient population in a multicenter study and a longer period of observation time.
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