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This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in athletes. The monograph presents the results of 5-year research program on ARVC/D supported by grants of both the European Commission and the NIH, which enabled the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and for sudden death prevention. A panel of top scientists, both European and Americans, contributed to this volume, which will be an essential reference for professionals and residents in cardiology, radiology, human genetics, and sport medicine.

Arrhythmia --- Heart --- Myocardium --- Etiology. --- Right ventricle --- Pathophysiology. --- Diseases. --- Cardiomyopathies --- Cardiomyopathy --- Myocardial diseases --- Myocardiopathies --- Myocardiopathy --- Cardiopulmonary system --- Cardiovascular system --- Chest --- Allorhythmia --- Arhythmia --- Arrhythmias --- Cardiac arrhythmia --- Dysrhythmia --- Irregular heart beats --- Heart beat --- Electric countershock --- Palpitation --- Diseases --- Cardiology. --- Human genetics. --- Medicine. --- Pathology. --- Human Genetics. --- Molecular Medicine. --- Internal medicine --- Disease (Pathology) --- Medical sciences --- Medicine --- Medicine, Preventive --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Genetics --- Heredity, Human --- Physical anthropology --- Health Workforce --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology

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This text atlas focuses on the pathology and molecular genetics of sudden cardiac death in the young and in athletes, presenting the state of the art in the field as the basis for development and implementation of more effective prevention strategies, including, ultimately, molecular therapy that will cure the underlying biological defect. A wealth of high-resolution color images, accompanied by clear supporting text, are presented to document the anatomic pathology of the cardiac diseases most frequently responsible for sudden cardiac death in this population, including coronary artery diseases, cardiomyopathies, myocarditis, valve diseases, conduction system abnormalities, congenital heart diseases, and ion channel diseases. The role of the molecular autopsy in overcoming the limitations of morphological investigations and offering new insights and avenues for prevention is explained. The approach is, however, interdisciplinary, with close attention also to epidemiologic and clinical aspects. The authors draw throughout on their experience gained over 30 years in the course of a prospective study carried out in the Veneto Region, North East Italy. This text atlas will be of great value not only for cardiologists but also for geneticists, sports physicians, and residents in cardiology and pathology.

Epidemiology. --- Cardiovascular Diseases --- Medicine --- Health & Biological Sciences --- Sudden death in children. --- Sudden death in adolescence. --- Cardiac arrest in children. --- Pediatric cardiology --- Teenagers --- Children --- Mortality --- Cardiology. --- Pathology. --- Sports medicine. --- Medicine. --- Radiology, Medical. --- Sports Medicine. --- Molecular Medicine. --- Imaging / Radiology. --- Diseases --- Public health --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Athletic medicine --- Athletics --- Medicine and sports --- Physical education and training --- Sports --- Sports sciences --- Disease (Pathology) --- Medicine, Preventive --- Heart --- Internal medicine --- Medical aspects --- Health Workforce --- Molecular biology. --- Radiology. --- Radiological physics --- Physics --- Radiation --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology

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Molecular biology --- Human genetics --- Pathology of the circulatory system --- Pathology --- medische genetica --- pathologie --- genetica --- cardiologie --- moleculaire biologie

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This text atlas focuses on the pathology and molecular genetics of sudden cardiac death in the young and in athletes, presenting the state of the art in the field as the basis for development and implementation of more effective prevention strategies, including, ultimately, molecular therapy that will cure the underlying biological defect. A wealth of high-resolution color images, accompanied by clear supporting text, are presented to document the anatomic pathology of the cardiac diseases most frequently responsible for sudden cardiac death in this population, including coronary artery diseases, cardiomyopathies, myocarditis, valve diseases, conduction system abnormalities, congenital heart diseases, and ion channel diseases. The role of the molecular autopsy in overcoming the limitations of morphological investigations and offering new insights and avenues for prevention is explained. The approach is, however, interdisciplinary, with close attention also to epidemiologic and clinical aspects. The authors draw throughout on their experience gained over 30 years in the course of a prospective study carried out in the Veneto Region, North East Italy. This text atlas will be of great value not only for cardiologists but also for geneticists, sports physicians, and residents in cardiology and pathology.

Molecular biology --- Epidemiology --- Social medicine --- Physical methods for diagnosis --- Pathology of the circulatory system --- Pathology --- Recreation. Games. Sports. Corp. expression --- pathologie --- cardiologie --- sportgeneeskunde --- epidemiologie --- radiologie --- medische beeldvorming --- moleculaire biologie

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Bandini, Fernando,