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book (4)


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English (4)


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2023 (3)

2020 (1)

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Book
Synucleins : Biochemistry and Role in Diseases
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ISBN: 1789845882 1789845653 Year: 2020 Publisher: IntechOpen

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Abstract

Neurodegenerative diseases are debilitating conditions that result in degeneration and death of nerve cells. A significant group of these diseases is the synucleinopathies, which are characterized by the accumulation of aggregates of alpha-synuclein in neurons, nerve fibers, or glial cells. There are three main types of synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Synucleins are small, naturally unfolded proteins prone to aggregate and form intracellular inclusions, which impair normal cellular functions. This book presents new data on synuclein aggregation and its effect on cholesterol transport. It also discusses the role of genetic contribution to these diseases and approaches to inhibition of synuclein aggregation.


Book
Possibilities and Limitations in Current Translational Stem Cell Research
Authors: ---
ISBN: 1837680337 Year: 2023 Publisher: London : IntechOpen,

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Abstract

Although the concept of using advanced therapy products such as stem cells seems to be a key strategy in the treatment of various diseases, much information in this area remains unknown. Stem cell products are highly complex, much more complex than chemical-based drugs. More and more often there are data indicating the risk of using stem cells. These risks are determined by various factors that are related to quality, biological activity, and the use itself, and thus administration. Therefore, it is very important to constantly systematize knowledge in this area. This book was created to present both the perspective of basic research, including the manipulation and changes in the properties of cells, and the changes and novelties in therapies themselves.


Book
Chitin and chitosan : isolation, properties, and applications
Authors: ---
ISBN: 1803566930 Year: 2023 Publisher: London : IntechOpen,

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Abstract

Polysaccharides are organic polymers in which the repeating unit consists of monosaccharides. They exist in plants, animals, algae, or microbial worlds. Chitosan is a cationic linear polysaccharide of glucosamine produced from chitin deacetylation in alkaline media. Chitin is obtained from the exoskeleton of shrimps, crabs, and squids. Therefore, chitosan is environmentally benign and biodegradable. This book summarizes different aspects of chitosan and its derived materials, addressing isolation, properties, and applications. This book is intended for academics, professionals, and scientists as well as graduate and undergraduate students without any geographical limitations.


Book
Chemokines Updates
Authors: ---
ISBN: 1803561742 Year: 2023 Publisher: London : IntechOpen,

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Abstract

This book provides an overview of some of the latest developments in the medical sciences, with particular emphasis on the experimental and theoretical aspects of modern medicine. In recent years, researchers working in applied health sciences have been able to identify diseases indicated by chemokines. Among the topics discussed in this book are chemokines affecting platelet functions, cytokine levels, and oxidative stress parameters in COVID-19, chemokines at the intersection of diabetes-tuberculosis synergy, chemokines in periodontal diseases, pathogenic links between hepato-digestive disorders and periodontal conditions, and IL-inflammatory carcinogenesis. Other areas included are the role of 23 receptor gene variations, the relationship between interleukin-5 Receptor polymorphism, and immunological parameters in children with asthma. The book's primary target audience includes students, researchers, medical practitioners, dentists, pharmacologists, and professionals interested in related fields. The book has been written by expert international scientists active in research in the health and applied sciences. We hope it will increase scientists' knowledge of the complexity of some medical approaches, and encourage both professionals and students to devote part of their future research to understanding the mechanisms and applications of chemokines.

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