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Book
Translating foreign otherness : cross-cultural anxiety in modern China
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ISBN: 9781138733282 9781315187686 9780367410773 Year: 2018 Publisher: London Routledge, Taylor & Francis Group

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Book
Translational spaces : towards a Chinese-Western convergence
Author:
ISBN: 9780367654788 9781003129622 Year: 2021 Publisher: London Routledge, Taylor & Francis Group

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Book
Translating Chinese art and modern literature
Authors: ---
ISBN: 9781138549203 9781138549210 9781351001243 9781351001236 9781351001212 9781351001229 135100123X 1351001213 1351001221 1351001248 Year: 2019 Publisher: London Routledge

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"Translating Chinese Art and Modern Literature examines issues in cross-cultural dialogue in connection with translation and modern Chinese art and literature from interdisciplinary perspectives. This comprises the text-image dialogue in the context of Chinese modernity, and cross-cultural interaction between modern literature in Chinese and other literatures. This edited collection approaches these issues with discrete foci and approaches, and the ten chapters in this volume are to be divided into two distinct parts. The first part highlights the mutual effects between literary texts and visual images in the media of book, painting, and film, and the second part includes contributions by scholars of literary translation"--


Dissertation
Large-scale prediction of protein-peptide interactions on protein surfaces
Authors: --- --- ---
Year: 2017 Publisher: Leuven KU Leuven. Faculteit Industriële Ingenieurswetenschappen

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Peptides are the smallest biological molecules of plant proteome often the size of 2 to 100 amino acids. Previously, many eukaryotic RNAs containing short open reading frames (sORFs) in eukaryotes were considered non-coding. However, several recent studies clearly indicate that sORFs can indeed translate into bioactive peptides. It was shown that several transcriptionally active regions (TARs) were induced upon by application of biotic (Botrytis cinerea) and abiotic stress (Paraquat) in Arabidopsis thaliana. These TARs could be translated into stress-induced peptides (SIPs). These SIPs can be either Botrytis cinerea induced peptides (BIPs) or Oxidative stress induced peptides (OSIPs) depending on the applied stress. Peptide-mediated interactions in which a short linear motif binds to a globular domain play a key role within the cell, mediating several cellular processes such as signal transduction and other regulatory pathways. These SIPs might play an important role in stress tolerance by interacting with a receptor protein. The main objective of this thesis is to carry out large scale predictions of peptide binding pockets on protein surfaces. In many cases, protein monomers have a specific function when interacting with a cofactor or ligand together. When a peptide encoded by a TAR binds at a known ligand or cofactor binding site, it may affect protein function. Moreover, for protein dimers or multimers, several peptides may bind at dimer interface of multi-chains and modulate its activity. In our current study, the peptide-protein docking method pepATTRACT-local was adopted, which combines a coarse-grained peptide docking protocol with atomistic refinement. The restraints used for dockings were obtained using peptide binding site prediction server PepSite2. 530 peptide-protein pairs were successfully docked and we screened out 104 top pairs using in-house scripts and manual observations. 30 peptides were found to bind to a known ligand/co-factor binding site and 17 peptides can bind to a pocket at the interface between two monomers of a multi-chain complex. To characterize peptide-protein interactions, top ten models corresponding to each of docked complex were extracted and analyzed using tools such as BINding ANAlyzer and HBPLUS. In an additional study, 104 screened peptide-protein pairs were docked without any restraints and the performance was tested against the previously docked complexes. It was found that 26 complexes were docked correctly in the same pockets by both pepATTRACT-local and pepATTRACT-blind docking. This dataset was classified as a high confidence set. Binding analysis revealed that most of the peptides interact with help of their sidechains on a specific pocket on the protein surface. Hydrophobic and hydrogen bonds stabilize much of the interactions between the receptor and peptides. Several peptides may target signaling proteins or interfere with biosynthetic enzymes thus, influencing their functions. We further investigated three types of proteins from the top docked complexes including herbicide target proteins, stress responsive enzymes like aldo-keto reductases and leucine-rich repeat receptor kinases. Molecular visualization software Chimera and PyMOL along with 2D ligand-protein interaction analysis software LIGPLOT were used for the analysis. In the current study, we have generated novel hypotheses on protein-peptide interactions which will help scientists to validate these interactions experimentally.

Keywords

Translation, Globalisation and Localisation
Authors: --- --- --- --- --- et al.
ISBN: 9781847690531 184769053X 9781847690548 1847690548 1281725730 9786611725730 9781281725738 6611725733 Year: 2008 Publisher: Bristol Blue Ridge Summit

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The global/local distinction has changed significantly, and the topic has been heatedly debated in literary and cultural as well as translation scholarship. In this age of globalisation, the traditional definition of translation has been altered. In the present anthology, translation is viewed as a cultural and political practice, and accordingly translation studies is based on a heightened awareness of global/local tensions in translation and of its moderating and transforming impact on local cultural paradigms. All the essays in this anthology deal with issues of translation from a cultural and theoretic perspective with regard to tensions and conflicts between global and local interests and values. No matter how different their approaches may seem, the essays are thematically integrated to discuss translation in a dialectical framework: either “globalising” Chinese issues internationally, or “localising” general and international issues domestically.


Book
Translating China
Authors: --- --- --- --- --- et al.
ISBN: 9781847691880 Year: 2009 Publisher: Bristol Blue Ridge Summit

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