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This book contains information for specialists in various fields of science. From the point of view of pharmacology, data are reported regarding the effect of echinochrome A and related metabolites from sea urchins on the survival and functional properties of stem cells, which can facilitate ex vivo application of this compound in medicine. For scientists who isolate and establish structures of marine natural compounds, an article devoted to the proof of the microbial origin of a typical metabolite earlier found exclusively from marine invertebrates, 6-epi-monanchorin, may also be of interest. A range of new marine metabolites was discovered from the both marine invertebrates and marine microorganisms, particularly in marine isolates of fungi. Some marine natural products could be applied to treat such diseases as Parkinson’s disease, ischemic stroke, viral infections, and so on. Magnificamide, a new peptide from sea anemones, inhibits porcine and human saliva amylases, showing its probable antidiabetic properties. Application of the genomic approach was discussed in studies on various marine bacteria, producing marine enzymes with unusual specificity. The lectins capable of recognizing glycoforms of different substrates demonstrate the possibility to be used to elaborate new medical diagnostics.
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This book contains information for specialists in various fields of science. From the point of view of pharmacology, data are reported regarding the effect of echinochrome A and related metabolites from sea urchins on the survival and functional properties of stem cells, which can facilitate ex vivo application of this compound in medicine. For scientists who isolate and establish structures of marine natural compounds, an article devoted to the proof of the microbial origin of a typical metabolite earlier found exclusively from marine invertebrates, 6-epi-monanchorin, may also be of interest. A range of new marine metabolites was discovered from the both marine invertebrates and marine microorganisms, particularly in marine isolates of fungi. Some marine natural products could be applied to treat such diseases as Parkinson’s disease, ischemic stroke, viral infections, and so on. Magnificamide, a new peptide from sea anemones, inhibits porcine and human saliva amylases, showing its probable antidiabetic properties. Application of the genomic approach was discussed in studies on various marine bacteria, producing marine enzymes with unusual specificity. The lectins capable of recognizing glycoforms of different substrates demonstrate the possibility to be used to elaborate new medical diagnostics.
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The books described marine glycoconjugates. Two articles concern microalgal metabolites such as steroid and sphingoid glycoconjugates, and a glycoprotein from a sea cucumber with interesting biological activities, respectively. One article discusses the fatty acid composition and thermotropic behavior of glycolipids and other membrane lipids of green macrophyte Ulva lactuca. Three articles cover lectin subjects. One review article analyzes perspectives of marine and freshwater lectins’ application in experimental oncology and the therapy of oncological diseases; another article describes the use of a sponge lectin in the construction of a recombinant virus. The third article concerns the function of the immunity of a lectin in producing this compound crinoid. Two articles concern steroid glycosides from star?sh, and two others concern triterpene glycosides from sea cucumbers. One article describes the e?ect of a glycosaminoglycan from the sea cucumber Apostichopus japonicus on hyperglycemia in the liver of insulin-resistant mice. One article concerns the isolation of 10 new triterpene glycosides from a fungus associated with a sea cucumber. The article by Dworaczek et al. characterizes the O-speci?c polysaccharide (O-antigen) of a bacterial pathogen of common carp by chemical and immunochemical methods. In total, the Special Issue comprises14 articles, including the editorial and two reviews.
n/a --- functions --- feather star --- Aeromonas --- glycosylceramides --- sghC1qDC --- O-antigen --- colony formation --- Bcl-2 proteins --- phospholipids --- sterol glycoconjugates --- Anthenea aspera --- glycosides --- Anneissia japonica --- cancer therapy --- secondary metabolites --- Echinoderm --- Apostichopus japonicus --- microalgae --- urease activity --- triterpene glycosides --- cytotoxic activity --- Alexandrium minutum --- Acremonium striatisporum --- betaine lipid --- signal transduction --- thermal adaptation --- Psolus fabricii --- O-polysaccharide --- oncolytic vaccinia virus --- N-Acetyllactosamine (LacNAc) --- l-perosamine --- differential scanning calorimetry --- Lethasterias fusca --- polyhydroxysteroids --- AMPK --- glycoprotein --- NMR spectroscopy --- glucose metabolism --- anti-biofilm activity --- ERK --- fish pathogen --- marine antiproliferative compounds --- lectin --- immunospecificity --- in vivo studies --- apoptosis --- distribution --- steroidal glycosides --- natural products --- biological activities --- Aphrocallistes vastus lectin --- marine fungi --- cell adhesion --- in vitro studies --- mass spectrometry --- psolusosides --- starfish --- sea cucumber --- glycosaminoglycan --- lipopolysaccharide (LPS) --- glycolipids --- fatty acids --- structures --- Akt --- diterpene glycosides --- body components --- structure --- mitophagy --- marine lectins --- crinoid --- cancer --- asterosaponins
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